Factors associated with Covid-19 deaths in records of 17M adult NHS patients

Post by simonh » Sat, May 16, 2020, 12:35 PM UTC

drak0n1c wrote: post #91

martingoodson wrote: post #46

Earlier quoted context omitted.

In case you weren't aware, controlled trials have shown that vitamin d supplementation protects against respiratory disease [1]. This is evidence that the association you highlight is more than a spurious correlation. It's likely to be causal. [1] https://www.bmj.com/content/356/bmj.i6583

If it's true that Vitamin D is such a large factor in reducing the lethality of respiratory disease -- perhaps it's better to loosen lockdown rules to ensure the wider population can get more sun before they inevitably catch the virus. It may explain why heavily indoors NYC had so many lethal cases, even as most infected were already keeping themselves indoors.

Post by Zach_the_Lizard » Sat, May 16, 2020, 12:39 PM UTC

0-_-0 wrote: post #117

mindviews wrote: post #26

Here's a link to the paper: https://www.medrxiv.org/content/10.1101/2020.05.06.20092999v... This is interesting data. I want to see Vitamin D status included in a large population study like this because I've been following two smaller studies covering about a thousand cases total that shows Vitamin D deficiency has a risk ratio of 10 to 20 (more even than being age 80+ in the above study). The studies: [1] https://p…

> I want to see Vitamin D status included in a large population study like this Although vitamin D is not mentioned in this study, it does show that black people have a hazard ratio of about 2 compared to whites. In the UK black people would be more vitamin D deficient than white people. Now that I think about it, isn't the potential for vitamin D deficiency the reason there are white people in the first place?

Post by wolfi1 » Sat, May 16, 2020, 1:03 PM UTC

mindviews wrote: post #26

Here's a link to the paper: https://www.medrxiv.org/content/10.1101/2020.05.06.20092999v... This is interesting data. I want to see Vitamin D status included in a large population study like this because I've been following two smaller studies covering about a thousand cases total that shows Vitamin D deficiency has a risk ratio of 10 to 20 (more even than being age 80+ in the above study). The studies: [1] https://p…

Post by elorant » Sat, May 16, 2020, 1:14 PM UTC

drak0n1c wrote: post #91

martingoodson wrote: post #46

Earlier quoted context omitted.

In case you weren't aware, controlled trials have shown that vitamin d supplementation protects against respiratory disease [1]. This is evidence that the association you highlight is more than a spurious correlation. It's likely to be causal. [1] https://www.bmj.com/content/356/bmj.i6583

If it's true that Vitamin D is such a large factor in reducing the lethality of respiratory disease -- perhaps it's better to loosen lockdown rules to ensure the wider population can get more sun before they inevitably catch the virus. It may explain why heavily indoors NYC had so many lethal cases, even as most infected were already keeping themselves indoors.

Post by [deleted] » Sat, May 16, 2020, 1:17 PM UTC

ip26 wrote: post #41

mindviews wrote: post #26

Here's a link to the paper: https://www.medrxiv.org/content/10.1101/2020.05.06.20092999v... This is interesting data. I want to see Vitamin D status included in a large population study like this because I've been following two smaller studies covering about a thousand cases total that shows Vitamin D deficiency has a risk ratio of 10 to 20 (more even than being age 80+ in the above study). The studies: [1] https://p…

The critical question remains though- is vitamin D the causal factor, or instead an indicator of something else?