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Factors associated with Covid-19 deaths in records of 17M adult NHS patients

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131–140 of 204 posts

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#131
post #66

Obligatory, "Fucking Twitter thread" complaint. I dread reading - Bullet point - After bullet point - In the form of a tweet per bullet point - Trying to skip the bullshit - And find the conclusion (I'll stop now) ...and having the anxiety to be disappointed that I'll read so much bullshit and end up with nothing. Yes, in the end he links to the abstract which has the (unfortunately harder to parse) meat, but also ye…

I fully agree with you, and therefore: a) the thread, in readable form https://threadreaderapp.com/thread/1258372975004389379.html b) the full publication https://www.medrxiv.org/content/10.1101/2020.05.06.20092999v...

threadreaderapp,com is great. Thank you for introducing me to it.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#132
post #117

Here's a link to the paper: https://www.medrxiv.org/content/10.1101/2020.05.06.20092999v... This is interesting data. I want to see Vitamin D status included in a large population study like this because I've been following two smaller studies covering about a thousand cases total that shows Vitamin D deficiency has a risk ratio of 10 to 20 (more even than being age 80+ in the above study). The studies: [1] https://p…

> I want to see Vitamin D status included in a large population study like this Although vitamin D is not mentioned in this study, it does show that black people have a hazard ratio of about 2 compared to whites. In the UK black people would be more vitamin D deficient than white people. Now that I think about it, isn't the potential for vitamin D deficiency the reason there are white people in the first place?

From NHS advice on vitamin D referenced in my previous comment

“Some people will not get enough vitamin D from sunlight because they have very little or no sunshine exposure.” .. “ If you have dark skin – for example you have an African, African-Caribbean or south Asian background – you may also not get enough vitamin D from sunlight.”

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#133

Notably, this research is being publicized by Ben Goldacre of Bad Science (among other accomplishments). Goldacre also gets last author on the non-alphabetized list of authors on the preprint, suggesting his primary involvement.

I wasn't familiar and looked him up. This might save others the effort. https://duckduckgo.com/?q=Ben+Goldacre+of+Bad+Science&t=fpas...

Down voted for helping others. HN...you've lost your mind. Your sense of community is an embarrassment.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#134

Earlier quoted context omitted.

As someone who relatively freshly started smoking 1.5 years ago, I find it insidious. After stopping for a day or two, I actually feel better as tension goes away and I sleep a lot. Shortly, however, I start randomly getting sneezes, runny nose, and slight ill-like feeling in my head. Part of what makes me start again is the desire to avoid spooking others with those flu-like symptoms in the middle of an epidemic, si…

This is a real effect. Smoking paralyses the cilia; about 4–6 days after cessation, the cilia become active again and start to bring up mucus from the lungs. The good news is that these symptoms are temporary. Public health communications on the benefits of cessation don’t usually mention this. I wonder if that’s a mistake. I would have thought it puts a lot of people off quitting, and maybe if they knew what was hap…

This is definitely useful to know. I reckon some smokers suffering from this upon withdrawal would suspect immunosuppression, and choose to continue.

When I have a week or so apart from the crowds, I’ll see how long it takes to push through those symptoms.

(I thought if withdrawal causes immune system suppression, this effect could explain the apparent COVID statistic correlation mentioned by 0-_-0 in parent comment, but from your information it’s unlikely to.)

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#135

Here's a link to the paper: https://www.medrxiv.org/content/10.1101/2020.05.06.20092999v... This is interesting data. I want to see Vitamin D status included in a large population study like this because I've been following two smaller studies covering about a thousand cases total that shows Vitamin D deficiency has a risk ratio of 10 to 20 (more even than being age 80+ in the above study). The studies: [1] https://p…

Is there any data showing which patients took D supplements (or daily multivitamin) vs having naturally normal/high levels? Medical people, does the answer matter?

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#136
post #119
post #93

Earlier quoted context omitted.

The old adage applies here: absence of evidence is not evidence of absence.

However, evidence of absence is unlikely to be found as the vast majority of researchers tend not to bother publishing papers with negative results. So if an idea seems like it should have been researched already, but no research papers are to be found, it may very well be because the evidence of absence simply hasn't been shared.

I wonder how many papers give a negative result because p was found to be .049 or so. I'm recalling that thread here a while back debating whether the statistical critical value is too high.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#137

Earlier quoted context omitted.

The thread is good, but a possible link with nicotine has been observed before. This might just be the unlikely case where smoking does indirectly confer some health benefit.

Maybe because it could cause you to go outside, increasing exposure to the sun.

Or cause sick people to avoid you. If I have a cold, no way I'm standing next to a smoker.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#138
post #109
post #74

Earlier quoted context omitted.

A friend of mine had cancer and they had him taking D3 immediately. also I was out shopping recently and they seemed to sell many varieties of D3, but I didn't see any other D vitamins offered for sale. Is D deficiency really D3 deficiency? or have the other D vitamins sold out?

As a vegan, I learned that there's D2 (comes from plants) and D3 (comes from animals), and they are the same as far as I know. Not sure about using them for treatments.

As a carnivore I’ve learned the same.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#139
post #80

Earlier quoted context omitted.

The thread is good, but a possible link with nicotine has been observed before. This might just be the unlikely case where smoking does indirectly confer some health benefit.

Nicotine must have some evolutionary benefit to the tobacco plant, perhaps it helps it resist the Tobacco mosaic virus.

Nicotine is an extremely powerful insecticide. That's the advantage to the plant.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#140

Earlier quoted context omitted.

Maybe because it could cause you to go outside, increasing exposure to the sun.

Or cause sick people to avoid you. If I have a cold, no way I'm standing next to a smoker.

Cause more than just sick people to avoid you. And people can see how far your smoke spreads so there's a visible warning to keep your distance.
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