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Factors associated with Covid-19 deaths in records of 17M adult NHS patients

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Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#14
post #11

What is "Deprivation" in this context?

I was wondering about that too. After some research it seems to be something like poverty. I.e., being deprived of decent living conditions, education opportunities employment opportunities, etc.

In the paper they used this index which measures deprivation by living location in the UK: https://en.wikipedia.org/wiki/Multiple_deprivation_index

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#15

What is a hazard ratio? Ie if the hazard ratio is 1.25 (for severe asthma), what does that mean concretely?

A hazard rate can be thought of as a patient's one day probability of mortality. A hazard ratio is a ratio of two hazard rates, so 1.25 would mean that people in one group were dying at a 1.25x rate relative to a comparison group.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#16

Notably, this research is being publicized by Ben Goldacre of Bad Science (among other accomplishments). Goldacre also gets last author on the non-alphabetized list of authors on the preprint, suggesting his primary involvement.

I wasn't familiar and looked him up. This might save others the effort.

https://duckduckgo.com/?q=Ben+Goldacre+of+Bad+Science&t=fpas...

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#17

From the paper: > The overall cumulative incidence of COVID-19 hospital death at 80 days from the study start date was How do those rates compare to the seasonal flu in the UK?

It is not very useful to compare them with flu because people are much more likely to have flu than to have covid. These rates seem very small but remember that the study started in the beginning of february, when there were likely only a handful if any covid carriers in the uk.

If you could preselect a group of people that you know had covid and measure their death rate, the numbers are likely to be much higher. This study did not do this. This is probably because this would require that all patients are tested for covid as they visit their doctor and this was obviously not happening.

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#19
I think one of the key takeaways is in the abstract:

> People from Asian and black groups are at markedly increased risk of in-hospital death from COVID-19, and contrary to some prior speculation is only partially attributable to pre-existing clinical risk factors or deprivation

Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients

#20
post #17

From the paper: > The overall cumulative incidence of COVID-19 hospital death at 80 days from the study start date was How do those rates compare to the seasonal flu in the UK?

It is not very useful to compare them with flu because people are much more likely to have flu than to have covid. These rates seem very small but remember that the study started in the beginning of february, when there were likely only a handful if any covid carriers in the uk. If you could preselect a group of people that you know had covid and measure their death rate, the numbers are likely to be much higher. Thi…

Thanks for the clarification. I got the gist from the paper that testing in this cohort was higher than it apparently was.
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