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New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

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Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#101
I took this test this Friday (Quest Direct) in NYC and tested negative.

In late Feb. I had a 'flu like symptoms' with fever and massive headache for few days. What worried me later is that I had the 'can't taste anything' symptom a week later. No coughing though.

If you read online, you see people swear they had it at some point this winter. So, if you had a 'flu like' symptoms in Feb or early March, perhaps it was just that...

It cost $110 and personally I think it was worth it... (it is a reminder myself to be more careful as I can still get it)...

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#102

I took this antibody test through LabCorp on Friday and tested positive. I have been in strict (see: paranoid) isolation with one other person since March 7 and haven't felt sick or anything close to it since then. I did have what I thought was a strange flu/cold early February with a sore throat, post-nasal drip, wildly varying body temperature, and lower back pains. In hindsight those are COVID-19 symptoms. the per…

Good anecdote. I also had a "weird cold" in February with symptoms that are unusual for me but typical of COVID-19, and have been waiting to get the antibody test. I kind of expect it to turn out the same way. (Otherwise, I would really like to figure out what the "weird cold" that everyone had in February was. Because it sure was weird, and everyone I know had it.)

took this test this Friday (Quest Direct) in NYC and tested negative. In late Feb. I had a 'flu like symptoms' with fever and massive headache for few days. What worried me later is that I had the 'can't taste anything' symptom a week later. No coughing though.

If you read online, you see people swear they had it at some point this winter. So, if you had a 'flu like' symptoms in Feb or early March, perhaps it was just that...

It cost $110 and personally I think it was worth it... (it is a reminder to be more careful as I can still get it)...

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#103
post #64
post #52

'Specificity and Sensitivity' are new words that are now going to enter the public consciousness with regards to testing. Before Iraq War 2, in 2003, absolutely nobody knew the difference between a 'Shia' or 'Sunni' Muslim, and then it became more common knowledge. It's neat to see how these events shape awareness. Now every time a Nurse does a test, people will ask "What's the specificity?!" which can be a good or b…

Specificity and sensitivity feel really poorly chosen and difficult to remember. You could swap their definitions and the names of the terms would make just as much sense. I much prefer true positive rate and true negative rate.

Yes, they are terrible terms for general usage!

Unfortunately, we don't choose our terminology from a public communications perspective. But it's obviously understandable why this is in hindsight.

I don't think people really need to have this level of detail nailed down anyhow, at this level, we'll have to just trust the system.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#104

Earlier quoted context omitted.

I agree with you on being open to thinking that COVID-19 arrived earlier than was initially thought. When I first shared my "weird cold" story on HN, the consensus was that I was a crazy person and there was no way that could be COVID-19. There would be more deaths if it had been here. But now there are some deaths, and a large number of people with "weird cold" stories, and it really makes me think that a lot of peo…

people say that because .25% of the population in NYC are dead from covid. we dont see those numbers here -- if it was widespread in feb, what caused the discrepancy?

different strains?

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#105

I took this test this Friday (Quest Direct) in NYC and tested negative. In late Feb. I had a 'flu like symptoms' with fever and massive headache for few days. What worried me later is that I had the 'can't taste anything' symptom a week later. No coughing though. If you read online, you see people swear they had it at some point this winter. So, if you had a 'flu like' symptoms in Feb or early March, perhaps it was j…

Did you have nasal congestion? If so, that could explain the loss of taste. The olfactory system plays a significant role in taste perception.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#106

Earlier quoted context omitted.

I agree with you on being open to thinking that COVID-19 arrived earlier than was initially thought. When I first shared my "weird cold" story on HN, the consensus was that I was a crazy person and there was no way that could be COVID-19. There would be more deaths if it had been here. But now there are some deaths, and a large number of people with "weird cold" stories, and it really makes me think that a lot of peo…

people say that because .25% of the population in NYC are dead from covid. we dont see those numbers here -- if it was widespread in feb, what caused the discrepancy?

I guess we need to know the total number of cases to figure out what the deaths mean, and until everyone has gotten an antibody test, we can't know that total number.

To make the numbers work for the "weird cold" in early February case, I guess we have to work backwards. Assume that when we went into lockdown was the actual peak, 8 million people in New York City had COVID-19. That means that there is one death for every 500 cases. Then we have to pick a reproduction rate, which I have no idea how to pick, so I'll say that it increases by 1.5x every day (so on day one you have x cases, then on day 2 you have x + 1.5x, then on day 3 you have x + 1.5x + (1.5)^2x, etc. Going back a month from March 20 (which is approximately 30 days, and when a lot of people report their "weird cold"), that would mean we'd expect around 8 million / 383500 = 20 cases on Feb. 20. With 1 death per 500 cases, you'd have 0 deaths at that level.

I know I've pulled these numbers out of my nether region and so they are likely very wrong. But with some back-of-the-envelope math, I think we can have some sick people in February without a lot of deaths.

Obviously my 8 million total cases in NYC number is too high, and the 20 cases on 2/20 is too low for me and my friends to be those cases. But that exponential can be tweaked to make something plausible. If we make it 1.2 instead of 1.5, then we should have had about 7000 cases on 2/20, and that means around 14 deaths. That seems quite plausible to me. So I dunno. There was a weird cold. It's weird. It could mean anything.

I signed up to get an antibody test. 1 test is not data, but it will be very interesting to see the results.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#107

Earlier quoted context omitted.

Good anecdote. I also had a "weird cold" in February with symptoms that are unusual for me but typical of COVID-19, and have been waiting to get the antibody test. I kind of expect it to turn out the same way. (Otherwise, I would really like to figure out what the "weird cold" that everyone had in February was. Because it sure was weird, and everyone I know had it.)

took this test this Friday (Quest Direct) in NYC and tested negative. In late Feb. I had a 'flu like symptoms' with fever and massive headache for few days. What worried me later is that I had the 'can't taste anything' symptom a week later. No coughing though. If you read online, you see people swear they had it at some point this winter. So, if you had a 'flu like' symptoms in Feb or early March, perhaps it was jus…

I also signed up for the test. Should be interesting.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#108
The Quest website warns that having the antibodies does not necessarily mean you are immune. Is it really likely that reinfection is possible less than a year after initial infection, or is that just something they have to write as a disclaimer?

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#109
post #108

The Quest website warns that having the antibodies does not necessarily mean you are immune. Is it really likely that reinfection is possible less than a year after initial infection, or is that just something they have to write as a disclaimer?

As a lay person, I think it is somewhere in the middle. In all likelihood antibody presence does mean some level of immunity or at least resistance. But testing is still only measuring presence of antibodies, not their efficacy in resisting future infections. Furthermore somebody who is reinfected but has antibody driven resistance may end up behaving as an asymptomatic case.

https://www.ibtimes.com/coronavirus-treatment-antibody-study...

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#110

Earlier quoted context omitted.

people say that because .25% of the population in NYC are dead from covid. we dont see those numbers here -- if it was widespread in feb, what caused the discrepancy?

different strains?

Viruses tend to become less lethal as time passes, not more.
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