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New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

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Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#61
post #34
post #31

Earlier quoted context omitted.

Reminder that at the moment this cannot happen without 1% of them dying and many more suffering long lasting or even permanent debilitation. If we ever get to the point where 80% of the population has had the virus, that would be a massive failure.

And the immunity may only last a year or two.

While there's no guarantee of long-lasting immunity, at the same time we do not know if the symptoms will be still as severe in reinfected people.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#62
post #59

Earlier quoted context omitted.

The FDA suggestion of doing two tests to reduce the percentage of false positives (since you can't rule out cross-reactivity with another coronavirus) looks like a good idea for broad testing. Of course this means higher costs.

> since you can't rule out cross-reactivity with another coronavirus If that causes a false positive, wouldn't a second test yield the same result?

A different test from a different company or whatever.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#63
post #39

I took this antibody test through LabCorp on Friday and tested positive. I have been in strict (see: paranoid) isolation with one other person since March 7 and haven't felt sick or anything close to it since then. I did have what I thought was a strange flu/cold early February with a sore throat, post-nasal drip, wildly varying body temperature, and lower back pains. In hindsight those are COVID-19 symptoms. the per…

I've been waiting for a decent serum test because both my wife and I had "the flu" with symptoms consistent with COVID-19, me in mid-January and her in late February. How did you get the test?

I had the same test through Circle Medical, was able make the appointment and get the test in the same day.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#64
post #52

'Specificity and Sensitivity' are new words that are now going to enter the public consciousness with regards to testing. Before Iraq War 2, in 2003, absolutely nobody knew the difference between a 'Shia' or 'Sunni' Muslim, and then it became more common knowledge. It's neat to see how these events shape awareness. Now every time a Nurse does a test, people will ask "What's the specificity?!" which can be a good or b…

Specificity and sensitivity feel really poorly chosen and difficult to remember. You could swap their definitions and the names of the terms would make just as much sense. I much prefer true positive rate and true negative rate.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#65
post #59

Earlier quoted context omitted.

The FDA suggestion of doing two tests to reduce the percentage of false positives (since you can't rule out cross-reactivity with another coronavirus) looks like a good idea for broad testing. Of course this means higher costs.

> since you can't rule out cross-reactivity with another coronavirus If that causes a false positive, wouldn't a second test yield the same result?

That can't be discounted, but if you have two tests that target different epitopes of the virus (hence, independent), the probability of them being wrong at the same time is

    p_false1 * p_false2 
(probability of independent events), hence much lower.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#66

I took this antibody test through LabCorp on Friday and tested positive. I have been in strict (see: paranoid) isolation with one other person since March 7 and haven't felt sick or anything close to it since then. I did have what I thought was a strange flu/cold early February with a sore throat, post-nasal drip, wildly varying body temperature, and lower back pains. In hindsight those are COVID-19 symptoms. the per…

Where does it say that LabCorp uses the Abbott Architect platform? Couldn't find it on their website. (Unlike, say, healthlabs.com)

you're right, it's hard to find that definitively online. however, it lists it on my emailed test results as well as a friend's who did it on the same day. that doesn't mean they're not using multiple test types though. maybe worth calling and asking if they use it everywhere?

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#68

I took this antibody test through LabCorp on Friday and tested positive. I have been in strict (see: paranoid) isolation with one other person since March 7 and haven't felt sick or anything close to it since then. I did have what I thought was a strange flu/cold early February with a sore throat, post-nasal drip, wildly varying body temperature, and lower back pains. In hindsight those are COVID-19 symptoms. the per…

Good anecdote. I also had a "weird cold" in February with symptoms that are unusual for me but typical of COVID-19, and have been waiting to get the antibody test. I kind of expect it to turn out the same way. (Otherwise, I would really like to figure out what the "weird cold" that everyone had in February was. Because it sure was weird, and everyone I know had it.)

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#69
post #45

Earlier quoted context omitted.

Because with a false positive antibody test then you can still contract and be a carrier. This is a problem for the immunity passport proposals (which I think are a terrible idea anyway, but that’s beside the point)

Why do you think immunity passports are a terrible idea? What else works better barring a long term vaccine?

If my job prospects are shut down because I don't have immunity, I'm going to try and get infected.

Re: New Abbott SARS-CoV-2 antibody test has 99.90% specificity and 100% sensitivity

#70

I took this antibody test through LabCorp on Friday and tested positive. I have been in strict (see: paranoid) isolation with one other person since March 7 and haven't felt sick or anything close to it since then. I did have what I thought was a strange flu/cold early February with a sore throat, post-nasal drip, wildly varying body temperature, and lower back pains. In hindsight those are COVID-19 symptoms. the per…

Good anecdote. I also had a "weird cold" in February with symptoms that are unusual for me but typical of COVID-19, and have been waiting to get the antibody test. I kind of expect it to turn out the same way. (Otherwise, I would really like to figure out what the "weird cold" that everyone had in February was. Because it sure was weird, and everyone I know had it.)

Same here, had a lingering cough for nearly a month. The other weird part is I had flu-like symptoms for 3-4 days before I had any congestion and a runny nose. I can't recall any other time I've had a cold that didn't result in congestion within 24 hours of the first sign symptoms like a cough or sore throat. Just an anecdote, won't know until I'm able to get tested.
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