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Age Reduction Breakthrough?

joshmitteldorf.scienceblog.com

121–130 of 426 posts

Re: Age Reduction Breakthrough?

#121
post #95

Earlier quoted context omitted.

What's wrong with not wanting to die?

Being dead is basically the equivalent experience as not having been born. I'm not terribly upset about all the things I missed before 1977 AD. Not sure why I should be too worried about what I'll miss when I'm gone.

That seems orthogonal to his question.

Re: Age Reduction Breakthrough?

#122
post #68

Earlier quoted context omitted.

Luck is not success.

Yes of course, Gates, Musk, Buffet, Ford, these are just evil mediocrities that got lucky, you are right. Anyone could have done what they did, but for lack of luck.

The parent comment didn't make any such claims or use any vulgarity. I think you are putting words in their mouth and taking a very uncharitable interpretation of what was said.

Re: Age Reduction Breakthrough?

#123
post #70

Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…

At risk of sounding absolutely insane: There's probably no way to prove that this hasn't happened. Anyone who realizes they're not aging normally would likely have taken on a new identity elsewhere for fear of: 1. being burned at the stake 2. being trialed in repeated experiments 3. being deified, and then subsequently being burned at the stake. --- I realize my comment sounds like a joke, but I'm entirely serious. I…

Probably, yes. I turn 40 this month, and was recently told by someone who just met me that I look 25. What exactly am I supposed to do differently now?

Re: Age Reduction Breakthrough?

#124

Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…

https://www.bbc.com/future/article/20140520-the-girls-who-ne...

> A handful of girls seem to defy one of the biggest certainties in life: ageing. He has identified four girls with this condition, marked by what seems to be a permanent state of infancy, a dramatic developmental arrest. He suspects that the disease is caused by a glitch somewhere in the girls’ DNA. His quest for immortality depends on finding it.

Re: Age Reduction Breakthrough?

#126
post #122

Earlier quoted context omitted.

Yes of course, Gates, Musk, Buffet, Ford, these are just evil mediocrities that got lucky, you are right. Anyone could have done what they did, but for lack of luck.

The parent comment didn't make any such claims or use any vulgarity. I think you are putting words in their mouth and taking a very uncharitable interpretation of what was said.

Fair enough, how do you interpret what he said? I removed the mild vulgarity, I agree it was not needed.

Re: Age Reduction Breakthrough?

#127
post #8

Earlier quoted context omitted.

It's not targeting you. It targeted at dumbasses with cash who are scared of dying.

Stated more charitably, it is targeted towards potential investors that see the potential in something that could improve the lives of millions and eventually billions of people.

If people are going to invest in significantly extending the lives of billions of people, are they also going to invest in drastically limiting human procreation? It seems pretty clear there are too many of us already...

Re: Age Reduction Breakthrough?

#128
post #67

Earlier quoted context omitted.

People who had this mutation could have died of causes other than aging.

My first thought too - maybe it's just wishful thinking, but the bible does talk about people who lived for thousands of years. We're prone to dismiss this as hyperbole from uneducated ancients, but maybe they actually did exist and this sort of thing was why.

> the bible does talk about people who lived for thousands of years

I don't remember anyone mentioned living for _thousands_ of years. There are plenty of characters that live for hundreds, though. It is believed that Abraham lived to the age of 175, while I believe there was one character that lived into the 300's, but I do not recall their name. It has been a while since I delved into the old testament.

Re: Age Reduction Breakthrough?

#129

Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…

To put it simply, a population with aging is more fit than a population without. The speed at which beneficial mutations in a population reach saturation in the gene pool is a function of the number of generations that have gone by. So we can expect some downward selective pressure on lifespan.

So then, once a population reaches "ideal" mutations, if that is possible, then wouldn't the opposite start happening?

Re: Age Reduction Breakthrough?

#130
post #70

Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…

At risk of sounding absolutely insane: There's probably no way to prove that this hasn't happened. Anyone who realizes they're not aging normally would likely have taken on a new identity elsewhere for fear of: 1. being burned at the stake 2. being trialed in repeated experiments 3. being deified, and then subsequently being burned at the stake. --- I realize my comment sounds like a joke, but I'm entirely serious. I…

this person exists--- his name is Jared Leto.
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