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Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

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Re: Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

#31

Post by [deleted] »

hn_throwaway_99 wrote: post #30
weiming wrote: post #19

HSV always seemed particularly poorly understood in the society to me, e.g. with many people getting it as children due to careless parents/extended family, and the benign branding of "cold sore" as if it is related to a cold. Given that the vaccine for 1 or 2 has proved to be extremely challenging, always wondered if the public simply being more well-informed on this topic could help reduce the incidence in the popu…

> e.g. with many people getting it as children due to careless parents/extended family Puhleeze. HSV is present in the majority of the population. Branding parents as "careless" because their children get it is ridiculous.

[deleted]

Re: Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

#32

Post by snazz »

toomuchtodo wrote: post #27
snazz wrote: post #25

Earlier quoted context omitted.

Given the extremely high rates of HSV-1 infection (roughly half of everyone 14-49 and more among older people [0]), I'm guessing that it would be difficult to eradicate it using a vaccine (although I'm certainly not an expert). As a side note, the HPV vaccine only protects against strains 16 and 18 (with some also providing protection against types 6 and 11). That covers the majority of the strains that cause cancer,…

> Given the extremely high rates of HSV-1 infection (roughly half of everyone 14-49 and more among older people [0]), I'm guessing that it would be difficult to eradicate it using a vaccine (although I'm certainly not an expert). True, it'd be similar to Australia where their cervical cancer rates will decline over decades as older people die and for younger people [1], the HPV vaccine uptake rate was very high. Folk…

I stand corrected on the number of strands of HPV that Gardasil 9 protects against. That's more comprehensive than I remembered (and I've also received it).

Thanks for correcting me!

Re: Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

#34

Post by 01100011 »

I am very curious to see where this research goes. At the risk of sounding like an absolute nut-case, I've been experiencing significant cognitive decline since getting divorced and becoming sexually active. Granted, I went through a traumatic experience(divorce), developed sleep apnea(treated for ~2 years), and am in my mid-40s, so my concerns are probably unfounded. That said, I've had my apnea under control for some time, I've gotten fit, and tried every combination of supplements I can think of. My hormones and blood work all look fine. Maybe I'll try some valacyclovir and see what happens.

Re: Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

#35

Post by SketchySeaBeast »

weiming wrote: post #19

HSV always seemed particularly poorly understood in the society to me, e.g. with many people getting it as children due to careless parents/extended family, and the benign branding of "cold sore" as if it is related to a cold. Given that the vaccine for 1 or 2 has proved to be extremely challenging, always wondered if the public simply being more well-informed on this topic could help reduce the incidence in the popu…

The rate of infection is 90% worldwide.[1] It's not just careless parents and lack of awareness, it's endemic to all of mankind.

Given that asymptomatic shedding occurs there's basically no way to not transmit herpes to your partner. Unless we remove kissing from our social norms, it's going to stick around.

[1]https://en.wikipedia.org/wiki/Epidemiology_of_herpes_simplex

Re: Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

#36

Post by selimthegrim »

snazz wrote: post #32
toomuchtodo wrote: post #27

Earlier quoted context omitted.

> Given the extremely high rates of HSV-1 infection (roughly half of everyone 14-49 and more among older people [0]), I'm guessing that it would be difficult to eradicate it using a vaccine (although I'm certainly not an expert). True, it'd be similar to Australia where their cervical cancer rates will decline over decades as older people die and for younger people [1], the HPV vaccine uptake rate was very high. Folk…

I stand corrected on the number of strands of HPV that Gardasil 9 protects against. That's more comprehensive than I remembered (and I've also received it). Thanks for correcting me!

It was updated IIRC (I don't know if the FDA has updated the indication to follow)

Re: Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

#38

Post by forgot_again »

01100011 wrote: post #34

I am very curious to see where this research goes. At the risk of sounding like an absolute nut-case, I've been experiencing significant cognitive decline since getting divorced and becoming sexually active. Granted, I went through a traumatic experience(divorce), developed sleep apnea(treated for ~2 years), and am in my mid-40s, so my concerns are probably unfounded. That said, I've had my apnea under control for so…

Make sure you get 8 hours of sleep each night. Eat healthy. Exercise daily. Keep anxiety in check.

Re: Using human brain tissue in lab, researchers show herpes link to Alzheimer’s

#40

Post by echelon »

weiming wrote: post #19

HSV always seemed particularly poorly understood in the society to me, e.g. with many people getting it as children due to careless parents/extended family, and the benign branding of "cold sore" as if it is related to a cold. Given that the vaccine for 1 or 2 has proved to be extremely challenging, always wondered if the public simply being more well-informed on this topic could help reduce the incidence in the popu…

> careless parents/extended family

> benign branding of "cold sore"

This is a dangerous, hurtful opinion and you need to be downvoted. No one is to be shamed for this virus.

A third of teenagers will acquire HSV-1 during childhood from simply putting things into their mouths. There is no way to prevent this sort of transmission. [1]

Most of the world's population has the virus. [2] Given these odds, you probably have the virus yourself and may or may not be asymptomatic.

The focus should be on finding a cure, not changing social norms or shaming people. The stigma is obstructing our focus. It's also impeding research, which as it may turn out, is a cause for Alzheimer's and related neurodegenerative disorders.

So much suffering from something that isn't anyone's fault, yet everyone blames "bad parenting" and "sexual promiscuity" for. It's shameful and we need to do better.

[1] https://www.cdc.gov/nchs/products/databriefs/db304.htm

[2] https://www.who.int/news-room/fact-sheets/detail/herpes-simp...

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