Earlier quoted context omitted.
What about an autonomous semitruck that could run 24 hours a day except for unloading/reloading cargo, refueling, and maintenance?
Trains. The fact that long haul semi trucks are a thing is a failure of infrastructure. Edit: as some have pointed out, it’s more a failure of policy.
https://grist.org/article/freight-trains-19th-century-techno...
Even if you electrify trucks the tire and brake wear and road degradation contribute an enormous amount of PM 2.5.
Sure you'll need trucks for the last mile but every ton of freight we can move to rails or waterways is a victory for humanity.