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Human body-on-chip platform could speed up drug testing

europeanscientist.com

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Re: Human body-on-chip platform could speed up drug testing

#31

Post by deathgrips »

meowface wrote: post #30
encephaloner wrote: post #29

Earlier quoted context omitted.

>Your world view is very bizarre to me the idea that people should simply live and die naturally is becoming increasingly antiquated >what society would ever produce decephalized humans when they could produce cephalized humans? a weak society that could not possibly adapt or grow. The primary driving force behind growth and change in society (by proxy of individuals attempting to fulfill the power process) is compet…

>the idea that people should simply live and die naturally is becoming increasingly antiquated Indeed, and I personally think that's a very, very good thing. Preventing aging and death is one of the most noble things we as a species can strive towards, in my opinion. I believe this should be the ultimate goal for all sentient beings, not just humans. I believe more and more people are coming to share this sentiment,…

>Preventing aging and death is one of the most noble things we as a species can strive towards, in my opinion. I believe this should be the ultimate goal for all sentient beings, not just humans.

The people I know who value nothing above their own lives have been without exception weak and deplorable. You can try and spin this as "preventing ALL deaths, not just mine" but in my experience it's just self-deception. People who can't psychologically handle their own deaths and subordinate it to other goals or principles are too weak to do so.

I'm not arguing against preventing aging. It might be a wonderful thing. But with few exceptions when talking to people who had been on the brink of death and destruction they all said it was the best part of their lives, some saying they would go back to it in an instant.

Re: Human body-on-chip platform could speed up drug testing

#32

Post by amankl »

echelon wrote: post #21

We need to clone decephalized humans and livestock. With thousands of brainless bodies kept alive on life support, you have test subjects for a limitless number of experiments that would have never been possible before. You also create a never-ending O negative blood supply and organ harvesting program. It the case of decephalized animals, you also get cruelty free meat. And that's how you bootstrap the program and p…

I've seen a lot here, but this takes the cake. I'm not sure if that post is a troll, assuming it is not:

Half of the energy and time of any decent person with morals goes into stopping smart psychopaths like that poster from doing whatever the heck they want.

I'm not religious, but it makes me wonder if the church is actually needed to keep those people in check.

Re: Human body-on-chip platform could speed up drug testing

#33

Post by joyj2nd »

echelon wrote: post #21

We need to clone decephalized humans and livestock. With thousands of brainless bodies kept alive on life support, you have test subjects for a limitless number of experiments that would have never been possible before. You also create a never-ending O negative blood supply and organ harvesting program. It the case of decephalized animals, you also get cruelty free meat. And that's how you bootstrap the program and p…

"With thousands of brainless bodies kept alive on life support," It is questionable, if you can do this without a brain.

Have you seen Elysium? https://en.wikipedia.org/wiki/Elysium_(film)

Re: Human body-on-chip platform could speed up drug testing

#34

Post by mattigames »

amankl wrote: post #32
echelon wrote: post #21

We need to clone decephalized humans and livestock. With thousands of brainless bodies kept alive on life support, you have test subjects for a limitless number of experiments that would have never been possible before. You also create a never-ending O negative blood supply and organ harvesting program. It the case of decephalized animals, you also get cruelty free meat. And that's how you bootstrap the program and p…

I've seen a lot here, but this takes the cake. I'm not sure if that post is a troll, assuming it is not: Half of the energy and time of any decent person with morals goes into stopping smart psychopaths like that poster from doing whatever the heck they want. I'm not religious, but it makes me wonder if the church is actually needed to keep those people in check.

If you want to be taken seriously you need to specify what morals is this violating exactly, it may be obvious to you but not to your readers.

Re: Human body-on-chip platform could speed up drug testing

#35

Post by ngla »

mattigames wrote: post #34
amankl wrote: post #32

Earlier quoted context omitted.

I've seen a lot here, but this takes the cake. I'm not sure if that post is a troll, assuming it is not: Half of the energy and time of any decent person with morals goes into stopping smart psychopaths like that poster from doing whatever the heck they want. I'm not religious, but it makes me wonder if the church is actually needed to keep those people in check.

If you want to be taken seriously you need to specify what morals is this violating exactly, it may be obvious to you but not to your readers.

As Shapiro says, you need to be taken seriously where it matters. If you sincerely need to ask which morals this violates, you show that you have no classical humanistic education. Such an education cannot be provided in a web forum.

It is sad that because of a couple of psychopaths tech people are not taken seriously outside of web forums.

Re: Human body-on-chip platform could speed up drug testing

#36

Post by mattigames »

ngla wrote: post #35
mattigames wrote: post #34

Earlier quoted context omitted.

If you want to be taken seriously you need to specify what morals is this violating exactly, it may be obvious to you but not to your readers.

As Shapiro says, you need to be taken seriously where it matters. If you sincerely need to ask which morals this violates, you show that you have no classical humanistic education. Such an education cannot be provided in a web forum. It is sad that because of a couple of psychopaths tech people are not taken seriously outside of web forums.

Is easy to claim the moral high ground when you don't define it, meaning where are you drawing the line? If I lose a leg in an accident and some scientists (plus doctors) can make a clone of my leg and my leg only to reattach it on my body is that moral or amoral? If yes then what about the complete lower body? If yes what about everything below the neck?

Re: Human body-on-chip platform could speed up drug testing

#37

Post by taffer »

hprotagonist wrote: post #3

If you can really, truly get liver-on-a-chip to work, it's going to positively change drug testing forever and will be the first huge win for tissue engineering. You can throw away animal models for tox screens forever, and that's great news. It will save vast amount of time and money. By using a much better proxy model for humans (slices aren't organs, they have different rheological characteristics and morphology,…

> It will save vast amount of time and money.

And it will prevent much animal suffering.

Re: Human body-on-chip platform could speed up drug testing

#38

Post by echelon »

amankl wrote: post #32
echelon wrote: post #21

We need to clone decephalized humans and livestock. With thousands of brainless bodies kept alive on life support, you have test subjects for a limitless number of experiments that would have never been possible before. You also create a never-ending O negative blood supply and organ harvesting program. It the case of decephalized animals, you also get cruelty free meat. And that's how you bootstrap the program and p…

I've seen a lot here, but this takes the cake. I'm not sure if that post is a troll, assuming it is not: Half of the energy and time of any decent person with morals goes into stopping smart psychopaths like that poster from doing whatever the heck they want. I'm not religious, but it makes me wonder if the church is actually needed to keep those people in check.

> I'm not sure if that post is a troll

It's not. I've had this idea for some time, and I'm absolutely serious.

We already grow human cells in culture. It's like growing an extremely delicate plant. The HeLa cell line is derived from Henrietta Lacks, and she's been dead for some time. There's nothing wrong with growing and manipulating cells like this. Eukaryotic cells are as brainless as prokaryotic ones. This is how we do basic research.

We create multicellular tissue cultures, often using the extracellular matrix from cadavers. Again, basic research. Nothing wrong, nobody hurt.

If you can grow a human body without a head and brain, how is that ethically different from a plant? Please explain it to me. As long as you guarantee the brain never develops, it's ethically cleaner than telling a white lie.

Personhood requires a brain. Period.

I don't believe in a soul. So that's not an issue either.

Next explain to me why we shouldn't do this, because headless clones will cut organ transplant waiting lists to zero and help us cure cancer, diabetes, and every other human disease that doesn't directly involve the brain.

Re: Human body-on-chip platform could speed up drug testing

#39

Post by alevskaya »

echelon wrote: post #21

We need to clone decephalized humans and livestock. With thousands of brainless bodies kept alive on life support, you have test subjects for a limitless number of experiments that would have never been possible before. You also create a never-ending O negative blood supply and organ harvesting program. It the case of decephalized animals, you also get cruelty free meat. And that's how you bootstrap the program and p…

I worked as a genetic engineer in human cell therapy: developmental biology doesn't really work that way. You can't just "decephalize" without causing massive secondary effects in body development and maturation - the nervous system is very much a central part and organizer of animal development, and also centrally important in a lot of the physiology you want to test when doing drug trials! And good luck keeping decephalized animals alive long enough to harvest outside a sterile lab. You don't need to be an edgelord billionaire to make a difference, but you'd benefit by learning more biology.

Re: Human body-on-chip platform could speed up drug testing

#40

Post by [deleted] »

echelon wrote: post #38
amankl wrote: post #32

Earlier quoted context omitted.

I've seen a lot here, but this takes the cake. I'm not sure if that post is a troll, assuming it is not: Half of the energy and time of any decent person with morals goes into stopping smart psychopaths like that poster from doing whatever the heck they want. I'm not religious, but it makes me wonder if the church is actually needed to keep those people in check.

> I'm not sure if that post is a troll It's not. I've had this idea for some time, and I'm absolutely serious. We already grow human cells in culture. It's like growing an extremely delicate plant. The HeLa cell line is derived from Henrietta Lacks, and she's been dead for some time. There's nothing wrong with growing and manipulating cells like this. Eukaryotic cells are as brainless as prokaryotic ones. This is how…

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