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Preliminary test results suggest 21% of NYC residents have Covid antibodies

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Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#321
post #166

Earlier quoted context omitted.

That isn't supported by any facts and is totally wrong. Our ability to treat viral pneumonia is very limited. We aren't saving 60-90% of patients that otherwise would die which your numbers imply. We can move the needle a bit and maybe save 20% of them. As an example, 90% of patients that go on ventilators still die. Even in a situation where hospitals are getting overwhelmed it won't make much difference. Much of th…

> As an example, 90% of patients that go on ventilators still die. That’s in New York, and probably because they only put the really worst cases on ventilators because there weren’t enough ventilators. In Germany, that number of deaths on ventilators is at around 30%. This shows that this quota is entirely useless to make your argument, and that maybe you should curb your intuition a bit when it comes to estimating p…

Do you have a cite for that 30% number?

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#322
post #295

Earlier quoted context omitted.

How about this article [1] (translation at reddit [2]) about german divers who had "mild cases" (no hospitalization, recovered at home) and were found to have suffered permanent lung damage, so severe that they can't dive anymore. [1] https://www.rainews.it/tgr/tagesschau/articoli/2020/04/tag-C... [2] https://www.reddit.com/r/Coronavirus/comments/g3rv7h/permame...

My ability to navigate Reddit is embarrassing. Never found the comment with the translation. Saw some of the discussion, though. Sounds like a promising lead to go down. I think my other criticisms are still unaddressed. Scarring damage is tough to place in age. Is plausible that they had some pre existing damage already. Funny to see the comments talk if walking pneumonia. I had that a decade ago. Was cake compared…

I think the fact that they used to dive but now can't kind of places most of the damage as recent.

My link should be a direct link to the comment. The bottom of the comment is hidden by default, but half of it is visible (and you can unhide the rest using the big blue button). I hate the new reddit design.

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#323
post #299

Earlier quoted context omitted.

0.18% of the entire NYC population is already dead from the coronavirus and by the time this is over the number will probably reach or exceed 0.3%. If you want the whole country to get herd immunity you will probably see similar mortality rates across the country. 0.3% of the US population is 1 million people. How have the models been proven to be "pessimistic by orders of magnitude?

Just so you know, around 3 million people die in the US every year, many of the million people you expect to die would have ended up being counted in that 3 million background statistic. More importantly, herd immunity is the ONLY solution on the table right now, the lockdown is not about stopping the virus in its tracks. It is about spreading it out over a period of time.

>the lockdown is not about stopping the virus in its tracks. It is about spreading it out over a period of time.

It's unclear what the lockdown is about at all since the government messaging has been incoherent. Many countries have (so far) succesfully contained the virus without herd immunity through contact tracing, and the US government has been making vague comments about pursuing something along those lines despite not doing anything to increase testing volumes to the levels necessary for contact tracing.

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#324

I'm starting to wonder if there aren't 2 (or more) transmission methods for this virus with differing symptoms. Aerosol transmission with 'I got a cold' type symptoms, and droplet transmission with 'I got the worst cold I've ever had' type symptoms.

Another factor couldd be where the virus load lands - in the lung or the throat.

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#325

Earlier quoted context omitted.

going 7 times doesn’t actually increase the likelihood 7x but your point still stands that they would be far more likely to get it

Well, sort of. The increase in likelihood of being sampled due to going to the store N times more than the average person is a function of N and P (the probability of being sampled in any given trip) such that f(N, P): (1 - ((1-P)^N)) / P For a large P you're right, but as P gets very small (let's say that in any given trip you have a 0.01% chance of being sampled) then the increase in likelihood of being sampled app…

They also said people who went to the grocery store 7x as much were 7x as likely to be infected which is what I think this person was replying to.

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#326
post #317

> In his press conference today, Governor Cuomo revealed the preliminary results of a first-phase antibody test that surveyed 3,000 New Yorkers over two days in 19 counties at 40 locations that included grocery and big-box stores. The sample suggests that 13.9% of New York State residents have the antibodies, meaning they had the virus at one point and recovered. Of the regions tested–Long Island, NYC, Westchester/Ro…

This was my thought exactly. Some of my friends in the Bay area got COVID-19 (confirmed positive tests) after quarantining for over two weeks at home and taking all of the precautions. The only place they had been was the grocery store, so they suspect that they got it there.

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#327

Earlier quoted context omitted.

Or truly random sampling that includes appropriate proportions of sub groups, e.g, socioeconomic status etc. Otherwise you have to know on all of the doors. But it's still a lot: for a 95% confidence level and 2% margin of error, for NYC you would need to test about 2,400 people. Assuming a response rate of 10%, you need to knock on 24,000 doors.

Wouldn't the ability to refuse taking the test introduce bias? i.e. the 10% that do take it still may not be representative of the entire population. Likely better than the grocery store sample, but still not ideal

Yeah, that is still an issue. You can offer compensation to incentivize participation. And you can pre-select your sample (instead of random door-to-door) and require multiple follow ups with the selected persons to reduce nonresponse bias.

You can also do a separate phone survey in addition to surveying the test participants. Questions like "Do you think you have had COVID?" and "How many times per week do you leave the house?". If the responses for the test participants vary significantly from the phone survey participants, you can try and weight your data accordingly.

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#328

So, at what point can we declare the lockdown to be a harmful overreaction and start opening countries up? Will we hold anyone accountable for models which proved to be pessimistic by orders of magnitude, causing implosion of economies around the world?

That the 0.5% death rate in NYC is not higher is _because_ of the pause. We saw the death rates spike at the peak of the curve. We saw the hospitals near total collapse. We even have an example of what would happen if we didn't flatten the curve (Northern Italy). We have another counterexample of California that shows NY's pause was late.

I guess Sweden is the counter-counter example. I think the US would have needed to have built out a far different medical system to achieve what they have.

For a few days at the end of March and beginning of April, the hospitals came so, so close to collapsing. Just a few more days up the curve and we would have run out of beds. (In reality, we did run out of beds, as you can see stories of many turned away from hospitals in those dark days, but it wasn't quite a systematic collapse).

All of this happened, we were here to record it. Models are models, and we're in the early days of a deadly, virulent, confusing pandemic. But there is no doubt that our reactions and solidarity saved lives. The imperfect models helped us get there.

Now, there is a more reasonable question of where do we go from here. For urban metropolis like NYC, I think a slow re-open like Germany. We slightly open the spigit so that 20% becomes 40% becomes 60% (and hopefully immunity is immunity) and we achieve herd protection (at great cost).

And likely the less dense, the slower we'll need to go (depending on hospital saturation).

I certainly will cheer the scientists who took the best information they had at the time and worked with the leaders to make the best decisions they could. Yes, I will indeed hold them "accountable".

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#329

Earlier quoted context omitted.

one problem with all these projections is that they all assume everyone is the same and that it is just a matter of chance. Not true in the least bit. those most susceptible get the disease first, those most sensitive die first - I believe the ratios will not stay the same, but continuously tick downwards

On the other part, those who are more vulnerable are more aware, and are implementing more measures in their daily living, hence they are not getting infected as much, currently. Hope it stays that way.

Not sure that makes any difference.

Not only are death rates sharply higher in older people, but their infection rates relative to the population are also higher as well.

Re: Preliminary test results suggest 21% of NYC residents have Covid antibodies

#330
post #30
post #16

Earlier quoted context omitted.

I had the opposite conclusion. There are between 10k-15k COVID-19 associated deaths in NYC, depending on how you count (the higher rate is consistent with the excess-mortality data, I believe). That by itself produces a range of ~0.56%-0.86% if you assume 21.2 % of NYC has been infected (larger range if you allow for some error on the infection rate, obviously). Moreover, we don't know what fraction of the currently-…

0.5% comes from Cuomo’s presentation [1]. Also your 50% seems very high to me. My understanding is that 50% is about the death rate of covid patients requiring ventilation, so the overall death rate of people hospitalised for covid must be well below that. Also if you factor this timing impact, you have the same timing impact on the denominator, i.e. people who are infected but haven't developped antibodies yet. [1]…

no, the death rate for ventilated covid patients is something like 80-90%. this is based on a NYC study published yesterday.
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