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Psilocybin Produced in Yeast

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Re: Psilocybin Produced in Yeast

#141

Post by monktastic1 »

smabie wrote: post #6
mikeg8 wrote: post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Also, since we already have 4-aco-dmt (which is virtually identical to psilocybin), so there's no real reason to extract.

Having had countless cubensis trips and a handful of 4-aco-dmt ones, I didn't find them very similar (and found the latter to be uniquely unpleasant). Perhaps I have weird chemistry, but I'm not alone. I would hate for others to miss out.

Re: Psilocybin Produced in Yeast

#142

Post by SketchySeaBeast »

mistermann wrote: post #124
colechristensen wrote: post #106

Earlier quoted context omitted.

You'll find nausea and vomiting in just about every discussion about consuming psilocybin mushrooms.

I know this statement is false, because I've read thousands of discussions. I challenge you to attempt to prove your assertion with evidence. If you make an attempt, you will quickly realize that you are objectively incorrect . And then, in light of that realization, perhaps there may be value in reviewing and contemplating, at length , your earlier statement: > Think about why these kinds of arguments are made on di…

https://psychedelicreview.com/why-do-magic-mushrooms-cause-n...

It would seem that at least some people think Nausea is a problem.

Re: Psilocybin Produced in Yeast

#143

Post by vitorbaptistaa »

ralusek wrote: post #110
kfrzcode wrote: post #44

Consciousness studies will be the next frontier and may bring our race further, faster, than space exploration. In my opinion.

I've never once heard a bit of insight from a psychonaut that was particularly game-changing. We're all connected, consciousness is an illusion, societal structures are somewhat arbitrarily defined, etc. These are the existential thoughts of teenagers. Life is just energy, energy is just vibrations, everything is a fractal, etc, these are just the existential speculations of people making baseless claims. Consciousne…

Clichés have this issue. They are the fruit of deep introspection by generations, but the end result feels so small that it can be easily ignored.

We are all connected. Love thy neighbor. Consciousness is an illusion. Yadda yadda. Boooring.

We hear them so much that we become numb and don't give them a second thought. Yeah, we are all connected. So what? I have more important things to do. And we do, of course. The rent is due, COVID-19, wars, and so on.

Then, at some point in people's lives, we stop and ask: why? What's the point in all of this? We get so lost in the day to day that it's hard to see the forest from the trees.

Psychedelics give you a different perspective. It's like going for a ride in your inner self. You might come out now just knowing these clichés, but feeling them. This difference is immense [1].

The same can be done via spirituality and meditation, but there are very few (if any) ways to experience these things as intensely and as quickly as with psychedelics. The challenge is applying these insights in your life, otherwise it's just a fun trip.

[1] https://www.nytimes.com/2015/03/29/world/americas/a-hallucin...

Re: Psilocybin Produced in Yeast

#144

Post by Fricken »

victords wrote: post #112
colechristensen wrote: post #49

Earlier quoted context omitted.

There are negative side effects from consuming the mushrooms which you don't get from purified psilocybin. Dosage is important. There isn't a way to test for potency which would ensure a reliable dose. Argument fallacies: * your anecdotal positive experiences * suggesting superiority because something is "from nature" * referring to "mistakes from the past" without naming any * suggesting superiority that "has been (…

If you're pointing out the argument fallacies, you should at least name the negative effects and provide some argument/proof.

It's much more fun and easy to tear apart someone else's argument than to build your own.

Re: Psilocybin Produced in Yeast

#145

Post by sysbin »

bawolff wrote: post #68
sysbin wrote: post #57

Earlier quoted context omitted.

> People with psychiatric disorders need spiritual journeys. Spiritual journeys heal and cleanse the mind, heal and cleanse the soul. Do not try to strip that away. No opinion on the article or yours but where are you getting this opinion? Why or how, do psychiatric disorders need spiritual journeys. Not all people believe in spiritual journeys or are capable of it. There is noting scientific about what you're sugges…

Many (most?) people taking this substance report having some sort of mystical/spiritual experience. I doubt they are actually convening with the divine, but whether/how/why the substance causes that affect in people is certainly a part of "science". I also don't think the spiritual journey aspect should be dismissed so lightly. Its being investigated to help depression. Perhaps inducing a "spiritual" state in people…

Please can you provide sources?

Re: Psilocybin Produced in Yeast

#146

Post by gwbas1c »

mikeg8 wrote: post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

I like how mushrooms taste, but my sister doesn't. Her husband even insisted that we don't serve any mushrooms at their wedding.

(Granted, it's been years since I last ate magic mushrooms. I loved the way they tasted, but I don't think it's fair for someone who doesn't like they way they taste to have to gag them down just for a trip. I can still remember how they tasted, and the wonderful visions I had.)

Mushrooms also don't store well.

Extracting psilocybin so it can be served in a more palatable and easily stored form is a good thing.

Re: Psilocybin Produced in Yeast

#147

Post by mx24 »

ralusek wrote: post #110
kfrzcode wrote: post #44

Consciousness studies will be the next frontier and may bring our race further, faster, than space exploration. In my opinion.

I've never once heard a bit of insight from a psychonaut that was particularly game-changing. We're all connected, consciousness is an illusion, societal structures are somewhat arbitrarily defined, etc. These are the existential thoughts of teenagers. Life is just energy, energy is just vibrations, everything is a fractal, etc, these are just the existential speculations of people making baseless claims. Consciousne…

> Consciousness as a useful frontier, in my opinion, will only have utility as it intersects with neuroscience and artificial intelligence.

So by neuroscience and artificial intelligence I'm guessing we can assume you're just referring to western science.

How about the Buddhists? Or the shamans in tribal societies around the world? Was there no utility in their understanding and manipulation of consciousness (which was often achieved through the use of psychedelics)? In many ways the shamans and other spiritual practitioners are far ahead of western science in terms of understanding consciousness. However, that is rarely acknowledged in western society, especially among technical folks such as ourselves. Western science is not the only valid way to understand reality.

Re: Psilocybin Produced in Yeast

#148

Post by Nursie »

pmoriarty wrote: post #86
Nursie wrote: post #81

Earlier quoted context omitted.

Distillation on home premises without proper safety procedures is a recipe for explosions and for contaminated/weird distillation products. I'm a home-brewer, and have cold-distilled a couple of things (you can get up to about 22% that way IIRC), but I'm good with it being a little difficult to get started distilling, from a safety standpoint.

"I'm good with it being a little difficult to get started distilling, from a safety standpoint." If you screw up home canning, you can get botulism, which can very easily kill you and anyone else who consumes it. Same if you simply store some home-made garlic olive oil in your refrigerator. Cook beans wrong and you could get very sick or even die. Cooking on a gas stove could result in your house catching on fire, or…

Few of these involve the possibility of significant explosion, which is one way in which they are different.

Re: Psilocybin Produced in Yeast

#149

Post by hammock »

ralusek wrote: post #108
andrew_xor_andy wrote: post #39

> the best chemical synthesis methods require expensive and difficult to source starting substrates This type of thing always amazes me about nature -- obviously all the ingredients necessary exist in the soil the mushroom is grown in! Yet the best we can do to mimic nature is get some hard-to-acquire substrates. It's so interesting how, given enough time, the universe can produce a self-replicating organism that can…

> all the ingredients necessary exist in the soil the mushroom is grown in I can't speak for mushrooms, but for plants, the vast majority of the mass actually comes from carbon in the air (breathes in CO2, takes the carbon, breathes out O2) and obviously water.

>Generally, plants make their food using the sun's energy (photosynthesis), while animals eat, then internally digest, their food. Fungi do neither: their mycelium grows into or around the food source, secretes enzymes that digest the food externally, and the mycelium then absorbs the digested nutrients.

https://www.for.gov.bc.ca/hfp/publications/00029/mushwhat.ht...

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