Live data from Hacker News

Untitled topic

news.ycombinator.com

171–180 of 382 posts

Re: undefined

#171
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

Even if this were approved for use, do you honestly think ODs won't happen? One of the most common drug deaths is from Tylenol.

Re: undefined

#172
post #88

Earlier quoted context omitted.

Verbatim quote from the President: "if things don’t go as planned, it’s not going to kill anybody." Edit: Yes, I realize what he probably meant . I know how meds work. I still think he should have chosen his wording more carefully.

I.e. even if the drug is ineffective, at least we know it doesn't have fatal side effects, because it has already been used widely and approved for malaria treatment after going through safety trials a long while ago. This is in contrast to experimental drugs, which don't just have questionable efficacy, but also unknown safety. It goes without saying that like all prescription drugs which have been proven safe, chlo…

It doesn't really go without saying. Otherwise pharmaceutical advertising wouldn't need copious safety warnings in every single commercial.

I don't think it's a good idea to take the President's happy talk at face value, but then I also didn't think it was ever a good idea to spend money on Trump University, or donating to Trump charities; on the other hand, enough people did that the matters ended up in court and the two branded entities mentioned above were both found to be liable for misinforming their customers/donors.

There are a lot of stupid folk among the public, and it is to them that scam artists like Jim Bakker or Alex Jones market quack cures. There's an appetite for quack cures because they seem affordable relative to the often-inaccessible costs of basic medical treatment, because we don't have a universal public health system in the USA. The sad fact is that people sell snake oil because there are fat profits to be made by doing so, even though most of us recognize such products as little better than placebos at best or dangerous at worst.

This is why we have product regulation, credentialing and so on; it's hard for people to personally assess the quality of every product or service and there are unscrupulous people who are willing to exploit that difficulty.

Re: undefined

#173

Earlier quoted context omitted.

The FDA approved emergency expanded access for inhaled nitric oxide a couple days ago, which has the same mechanism of action as garlic and beet root. There is actually a plausible mechanism of action there, and a bunch of in vitro research.

Post a link because I right now I have no reason to believe you.

[deleted]

Re: undefined

#174

Isn't this medication decades old? Why would this suddenly be causing unexplained deaths in some stories while other stories indicate this: "Florida man with coronavirus says drug touted by Trump saved his life" https://nypost.com/2020/03/22/florida-man-with-coronavirus-s...

Old enough that we know:

> Chloroquine is very toxic in overdosage; overdosage is extremely hazardous and difficult to treat. Urgent advice from the National Poisons Information Service is essential. Life-threatening features include arrhythmias (which can have a very rapid onset) and convulsions (which can be intractable).

Self-medicating can easily lead to overdosing, especially when using a drug with a low therapeutic index like chloroquine.

https://bnf.nice.org.uk/drug/chloroquine.html

Re: undefined

#175
Nassim Nicolas Taleb had a tongue in cheek remark in his book, 'the reason religion was popular in middle ages is because it kept people away from doctors'. this reminds me of that.. not that religion fares much better these days.

Re: undefined

#176
post #24
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

I'm inclined to argue about the title "most powerful nation on this planet". It's a nice tagline, but the metrics for which it applies are narrowing rapidly. But still, let this be a lesson to those who would follow bad leaders to their own demise; or rather, let it be a lesson to their offspring who watch them follow the bad leaders. I suspect humanity follows cycles of enlightenment, complacency, and self-destructi…

> I'm inclined to argue about the title "most powerful nation on this planet".

Richest underdeveloped country? Most powerful failed state?

Re: undefined

#177
post #44

Earlier quoted context omitted.

It's been tested for years (decades? it's generic) as an anti-malaria drug. Any drug can be overdosed.

It hasn’t been tested against Covid-19. Recommending (or even vaguely hinting) that people just try random drugs that the FDA has approved for other uses is not a strategy with no downside.

Prescription drug = a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Personal responsibility = the idea that human beings choose, instigate, or otherwise cause their own actions.

Stupidity = behavior that shows a lack of good sense or judgment.

Re: undefined

#178
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

[deleted]

Re: undefined

#179

Isn't this medication decades old? Why would this suddenly be causing unexplained deaths in some stories while other stories indicate this: "Florida man with coronavirus says drug touted by Trump saved his life" https://nypost.com/2020/03/22/florida-man-with-coronavirus-s...

[deleted]

Re: undefined

#180
post #14

Did the chloroquine or COVID kill him? Did he even have COVID? Feel like this might be "tourniquet kills trauma victim", not sure though.

If anything it should be a wake up for the people (including on this very forum) who keep saying "why not just pop some pills and see what works, what could possibly go wrong?". Well, that's what.

How many people are realistically saying that? Most people are saying, let doctors experiment with what might work and don't stand in their way. Which they already have been doing anyhow with various other drugs. No one (at least not 99.99% of people) are saying go out and buy a drug and pop it to see if it saves you.
Post reply on HN