241–250 of 269 posts
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This drug accumulates in various tissues, so for retinopathy what matters is the cumulative amount of the drug consumed over time.
oh man ! just like excess of vitamin-d can lead to vitamin-d toxicity, so can this. in my naïveté, i was assuming that excess of it would be just flushed out.
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> each day along with a zinc pill. The scientific studies being cited for these COVID-19 vaccines using Chloroquine specifically state zinc supplements by themselves are not ionized and are therefore useless for fighting the virus. Even though zinc entering cells is a key part of how it works, zinc can't enter the cells in question unless it's properly ionized, which is why they use Chloroquine... an ionized zinc del…
Zinc supplementation is an effective treatment against many commonly found viruses. Are you saying the new virus is an exception to this? Seriously curious, as I haven't looked into it specifically. Also: Gargling a zinc/water solution has an astringent effect and removes the bacterial film in your throat, which seems to help in the initial phase of an infection.
There was a video of a doctor breaking down the biochemistry of it that got posted here the last time Chloroquine came up, which I can't find just now.
If it were only just as easy as taking zinc pills... I take vitamins daily already just to be safe (there's far more than coronaviruses floating around). I just don't expect them to be enough to prevent something as serious as COVID-19. There's a reason Chloroquine is being studied and not zinc by itself and is 100x more expensive to buy on the internet than zinc supplements, even before it became a meme. It's just not that simple.
That hasn't stopped naturopathy from spreading before though.
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> each day along with a zinc pill. The scientific studies being cited for these COVID-19 vaccines using Chloroquine specifically state zinc supplements by themselves are not ionized and are therefore useless for fighting the virus. Even though zinc entering cells is a key part of how it works, zinc can't enter the cells in question unless it's properly ionized, which is why they use Chloroquine... an ionized zinc del…
Pangolins aren’t the source and I’m not even gonna bother to explain.
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> ... has a cumulative dose of more than 1000 grams. ... woowza a Kg worth of drug !!! this doesn't look correct to me !
People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity 400mg/day for 5 years is 730 grams.
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People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity 400mg/day for 5 years is 730 grams.
only if everything gets stored, and there is no chance for that
has a cumulative dose of more than 1000 grams
And the calculator they link out to gives the same number I calculated.
This is an increadibly potent drug with serious side effects according to anything I read, its not first-line treatment its last-line, when everything else fails. You can go blind, irreversibly. Please people, speak to trained medical people before reaching to the drug cabinet. I am not a doctor. This advice is not meant to contradict the rule of only taking medical advice from medical professionals.
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> Why didn’t gain it more traction? It did. Since then they've done more studies, have started even more studies, and have deployed it en masse as a treatment. It's part of the official treatment recommendations in China, South Korea, Poland, and Italy. It's been described as a "cure" where it was used in Australia after Chinese patients demanded they be treated with it, and Australia is starting a nationwide trial.…
But Italy is a mess... So it is not an actual cure?
Chloroquine seems to work best if you start it within the first few days of infection. So if you are say the US and have widespread BS regarding testing and prevent people from getting it, by the time they are tested and their results back it's too late. There's no chance the US will come to their senses and start using or even producing this drug in time to help stop mass deaths. Some people bought animal grade chloroquine and are self treating, but all that supply is gone now for purchase. Doctors won't prescribe it in the US either, for their own reasons.
In China and South Korea you can get tested if you have symptoms and you can start treatment if you have symptoms. So we are seeing things turn around in both places because of this and other actions.
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To the plus side, its cheap. So, absent drug companies motivations to make cheap drugs (low) it is affordable at scale, and if it turned out to be useful e.g. early in the stage of the disease, this might be very good for wild infections. Or, maybe it points to drugs which are safer, equally cheap, and able to be made with less side effects. (see rule one: this is not medical advice)
Cheapish - as I recall about $300 for 90-day supply of generic hydroxychloroquine if paying cash in US. I mean, not cancer drug spends but if you are on it for life it’s an annoying annual expense.
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US drug prices are pretty crazy. A random search in an internet pharmacy shows 100 tablets of 200mg hydroxychloroquine is like 30€ in Germany.
I believe its around $30 in the US at Ralphs or Costco
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> Why didn’t gain it more traction? It did. Since then they've done more studies, have started even more studies, and have deployed it en masse as a treatment. It's part of the official treatment recommendations in China, South Korea, Poland, and Italy. It's been described as a "cure" where it was used in Australia after Chinese patients demanded they be treated with it, and Australia is starting a nationwide trial.…
But Italy is a mess... So it is not an actual cure?