> "The vast majority of people infected with Covid-19, between 50 and 75%, are completely asymptomatic but represent a formidable source of contagion". The Professor of Clinical Immunology of the University of Florence, Sergio Romagnani > Asymptomatic infection has been reported, but the majority of the relatively rare cases who are asymptomatic on the date of identification/report went on to develop disease. The pro…
The Italian number (75%) comes from testing everyone in a village of 3000 people. The Chinese number (1%) comes from testing everyone who comes to hospitals and maybe their family members. I would guess that the Chinese sample was selected for people displaying symptoms (asymptomatic people will not go to the clinic), while the Italian number biases for people early in the course of the disease. For the purposes of p…
50% – 75% of cases of Covid-19 are asymptomatic
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Re: 50% – 75% of cases of Covid-19 are asymptomatic
#72"Everyone we found to have Covid-19 had serious symptoms, so we don't want to waste money testing you if you don't!" I feel this is a trillion dollar mistake, testing more aggressively like South Korea means that you don't have to deploy the army and quarantine people. I had mild symptoms and they refused to test me, what am I to do? Self quarantine without a notice and hence without pay? I could work from home, but…
> Self quarantine without a notice and hence without pay? If you have symptoms of _any_ illness you should always get a sick leave and stay at home. It does not matter if it's covid, seasonal flu or just a common cold - sick leave and stay at home.
Re: 50% – 75% of cases of Covid-19 are asymptomatic
#73> "The vast majority of people infected with Covid-19, between 50 and 75%, are completely asymptomatic but represent a formidable source of contagion". The Professor of Clinical Immunology of the University of Florence, Sergio Romagnani > Asymptomatic infection has been reported, but the majority of the relatively rare cases who are asymptomatic on the date of identification/report went on to develop disease. The pro…
The Italian number (75%) comes from testing everyone in a village of 3000 people. The Chinese number (1%) comes from testing everyone who comes to hospitals and maybe their family members. I would guess that the Chinese sample was selected for people displaying symptoms (asymptomatic people will not go to the clinic), while the Italian number biases for people early in the course of the disease. For the purposes of p…
https://grapevine.is/news/2020/03/15/first-results-of-genera...
Re: 50% – 75% of cases of Covid-19 are asymptomatic
#74I wonder if this will be like H1N1. At first we only identified extreme cases and we had these terrifying reported fatality rates. Then we identify more and more mild or asymptomatic cases and the rates drop and drop. We’ve already seen how CFR was reported as 3 or 4%. Then on the cruise ship full of people over 60 it’s 0.7%. If there are lots of mild or asymptomatic cases it will likely be much lower. H1N1 was ident…
Re: 50% – 75% of cases of Covid-19 are asymptomatic
#75We've known this for a while. Everyone will get it. You might have it now. Nothing will happen. Still, quarantine for a while because you'll give it to an older person or kid. This isn't about a 20-something year old getting sick. Let your anti-bodies make yourself non-contagious. We are all kindergartens and this is chickenpox basically.
Re: 50% – 75% of cases of Covid-19 are asymptomatic
#76I wonder if this will be like H1N1. At first we only identified extreme cases and we had these terrifying reported fatality rates. Then we identify more and more mild or asymptomatic cases and the rates drop and drop. We’ve already seen how CFR was reported as 3 or 4%. Then on the cruise ship full of people over 60 it’s 0.7%. If there are lots of mild or asymptomatic cases it will likely be much lower. H1N1 was ident…
I really, really hope so. My hope is it is way more widespread than we think, and while that means it's going to be near impossible to contain, the denominator is so large that the CFR ends up being much lower than expected.
Re: 50% – 75% of cases of Covid-19 are asymptomatic
#77Earlier quoted context omitted.
> Self quarantine without a notice and hence without pay? If you have symptoms of _any_ illness you should always get a sick leave and stay at home. It does not matter if it's covid, seasonal flu or just a common cold - sick leave and stay at home.
I mean, sure, if you have sick leave. The above comment is perhaps aspirational, but otherwise it is woefully ignorant of the sad, sad state of US healthcare for most of its residents.
Every place on the planet needs to rethink how we handle infectious diseases. This requires both a cultural and legal shift, so that one can just not come to work when showing mild symptoms and not face any negative consequences. The market will not make this happen on its own. But this is a golden opportunity for the cultural shift - every society on this planet is going to be deeply scarred by SARS-CoV-2.
Re: 50% – 75% of cases of Covid-19 are asymptomatic
#78Earlier quoted context omitted.
I really, really hope so. My hope is it is way more widespread than we think, and while that means it's going to be near impossible to contain, the denominator is so large that the CFR ends up being much lower than expected.
If Covid-19 does end up being a dud, then we are in real trouble if/when an actual pandemic arrives -- because by then everyone will say the CDC is Crying Wolf.
Re: 50% – 75% of cases of Covid-19 are asymptomatic
#79Re: 50% – 75% of cases of Covid-19 are asymptomatic
#80Earlier quoted context omitted.
That means 1-2 million deaths in the US according to the latest modelling from Imperial Collage London, so it’s likely all countries will proceed to full lockdown for months at some point soon.
Any chance you could link to those models? I searched around and couldn't find them.
Perhaps our most significant conclusion is that mitigation is unlikely to be feasible without emergency surge capacity limits of the UK and US healthcare systems being exceeded many times over. In the most effective mitigation strategy examined, which leads to a single, relatively short epidemic (case isolation, household quarantine and social distancing of the elderly), the surge limits for both general ward and ICU beds would be exceeded by at least 8-fold under the more optimistic scenario for critical care requirements that we examined. In addition, even if all patients were able to be treated, we predict there would still be in the order of 250,000 deaths in GB, and 1.1-1.2 million in the US.