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Chloroquine has shown apparent efficacy in treatment of Covid-19

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Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#81

Post by signa11 »

tiredofit wrote: post #62
ggm wrote: post #44

This is an increadibly potent drug with serious side effects according to anything I read, its not first-line treatment its last-line, when everything else fails. You can go blind, irreversibly. Please people, speak to trained medical people before reaching to the drug cabinet. I am not a doctor. This advice is not meant to contradict the rule of only taking medical advice from medical professionals.

From wikipedia. One of the most serious side effects is a toxicity in the eye (generally with chronic use).[11] People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. The daily safe maximum dose for eye toxicity can be computed fro…

> ... has a cumulative dose of more than 1000 grams. ...

woowza a Kg worth of drug !!! this doesn't look correct to me !

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#82

Post by emayljames »

lacker wrote: post #75
ggm wrote: post #44

This is an increadibly potent drug with serious side effects according to anything I read, its not first-line treatment its last-line, when everything else fails. You can go blind, irreversibly. Please people, speak to trained medical people before reaching to the drug cabinet. I am not a doctor. This advice is not meant to contradict the rule of only taking medical advice from medical professionals.

You can just buy it over-the-counter in some countries, right? How dangerous can it really be? Follow the instructions on the box like citizens of those countries do. IMO we in the US need to take the coronavirus as a wake up call to stop ignoring the medical systems of other countries and admit that they might have something to teach us. We shouldn’t just assume the American medical system is always the best one.

The US medical system is only great to those that don't have to go through great struggles to afford it. It is the worlds worst and most dystopian to everyone else (the majority).

Financial status deciding who gets health care is the ultimate death panel.

The US health care system is awful in all ways.

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#83

Post by monocasa »

ggm wrote: post #44

This is an increadibly potent drug with serious side effects according to anything I read, its not first-line treatment its last-line, when everything else fails. You can go blind, irreversibly. Please people, speak to trained medical people before reaching to the drug cabinet. I am not a doctor. This advice is not meant to contradict the rule of only taking medical advice from medical professionals.

I guess I don't know the doses involved, but it's not that bad on it's face. I took it as an antimalarial for a few months.

Worst part is that it gives you weird dreams that puts you into a weird, almost bad trip head space.

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#85

Post by Johnny555 »

signa11 wrote: post #81
tiredofit wrote: post #62

Earlier quoted context omitted.

From wikipedia. One of the most serious side effects is a toxicity in the eye (generally with chronic use).[11] People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. The daily safe maximum dose for eye toxicity can be computed fro…

> ... has a cumulative dose of more than 1000 grams. ... woowza a Kg worth of drug !!! this doesn't look correct to me !

People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity

400mg/day for 5 years is 730 grams.

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#86

Post by reitzensteinm »

signa11 wrote: post #81
tiredofit wrote: post #62

Earlier quoted context omitted.

From wikipedia. One of the most serious side effects is a toxicity in the eye (generally with chronic use).[11] People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. The daily safe maximum dose for eye toxicity can be computed fro…

> ... has a cumulative dose of more than 1000 grams. ... woowza a Kg worth of drug !!! this doesn't look correct to me !

A kg isn't necessarily that much over a lifetime. I'm over that with at least one drug.

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#87

Post by skrebbel »

lacker wrote: post #75
ggm wrote: post #44

This is an increadibly potent drug with serious side effects according to anything I read, its not first-line treatment its last-line, when everything else fails. You can go blind, irreversibly. Please people, speak to trained medical people before reaching to the drug cabinet. I am not a doctor. This advice is not meant to contradict the rule of only taking medical advice from medical professionals.

You can just buy it over-the-counter in some countries, right? How dangerous can it really be? Follow the instructions on the box like citizens of those countries do. IMO we in the US need to take the coronavirus as a wake up call to stop ignoring the medical systems of other countries and admit that they might have something to teach us. We shouldn’t just assume the American medical system is always the best one.

> You can just buy it over-the-counter in some countries, right? How dangerous can it really be?

That's absolutely meaningless, some countries are nuts. Just about anything gets sold over the counter somewhere. There's even countries where guns are sold over the counter.

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#88

Post by hexl »

Gatsky wrote: post #71
monkeygus wrote: post #34

i currently take Plaquenil (Hydroxychloroquine) for rheumatoid arthritis, and my doctor did indicate it may be helpful against Covid but not enough tests to confirm. Is it close enough to chloroquine to be the same ?

Yes. Apparently the possible utility of chloroquine was discoevered because SLE patients on it in China weren't getting Covid-19 during the outbreak.

Source?

Re: Chloroquine has shown apparent efficacy in treatment of Covid-19

#90

Post by fspeech »

signa11 wrote: post #81
tiredofit wrote: post #62

Earlier quoted context omitted.

From wikipedia. One of the most serious side effects is a toxicity in the eye (generally with chronic use).[11] People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. The daily safe maximum dose for eye toxicity can be computed fro…

> ... has a cumulative dose of more than 1000 grams. ... woowza a Kg worth of drug !!! this doesn't look correct to me !

This drug accumulates in various tissues, so for retinopathy what matters is the cumulative amount of the drug consumed over time.
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