Just to check the source, these are the same slides (same Drive doc) tweeted by the listed author on the slides [1], who is a neurobiology and bioengineering professor at Stanford. If you want an understandable, relatively short but info-dense writeup from a sober expert (there hasn’t been much of this on HN) this is nice. [1] https://mobile.twitter.com/michaelzlin?lang=en
Is there a non Twitter source for this? Twitter is not working (for me) today.
How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
61–70 of 77 posts
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#62The comparison of symptoms on slide 26 seems particularly useful.
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#63Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#64> 95% don’t need to go to the hospital Including people who get at asymptomatically, maybe. Of people who get any symptoms, it's 15 - 20%. And even if you're not in that 15 - 20%, you may still have permanent or long lasting lung and heart damage. Stay inside; your grandparents were asked to go to war for several years, you're just being asked to spend a couple months playing video games.
I would encourage folks to go outside run, bike, hike, etc. There's plenty of healthy options that won't put you at risk from contracting the virus.
Except that most of the world doesn't live in an American suburb where houses are 100 meters apart. For most of the world, going outside means bumping into somebody.
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#65I'd like to see more information on what to do if you are sick. Even younger people have gotten serious respiratory complications and it would be great to have information on how to care for yourself or your family short of heading to the hospital and contributing to the overwhelming of their staff.
Respiratory illnesses are my achilles heel. One thing I always have on hand is Primatene. The guaifenesin loosens up mucus and the ephedrine opens up your respiratory tract so it's easier to breath--both improving nasal congestion, and also, AFAIU, helping with oxygen uptake in inflamed lungs. I have to be proactive because a simple cold can lead to bronchitis, and bronchitis can lead to pneumonia.
Any doctors, please opine, but I believe that if you have pneumonia (obvious infection, shortness of breath, etc) and are unable to get medical treatment, having some ephedrine on hand might be worthwhile. A quick search through the medical literature shows that ephedrine is apparently used precisely to improve oxygenation for acute respiratory distress (not just for asthmatics, obviously, but sometimes in surgery and in other cases).
The critical question would be counter-indications. The doctors I've run my cold treatment by always remind me that Guaifenesin and ephedrine both increase blood pressure, so that's something to keep in mind. (Fortunately, I don't have high-blood pressure.) But how that would figure into an acute distress situation, I dunno. I'm sure that in any particular context doctors probably know of many other counter-indications.
Primatene, Bronkaid, and similar generics are the only way to get ephedrine OTC, and they always include guaifenesin, so be mindful of dosages for both drugs. I just picked up a box of Primatene just in case as I forgot how much I had left at home. They're usually on the front shelves behind the pharmacist; don't bother hunting for one of the placards in the store aisle.
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#66Earlier quoted context omitted.
I would encourage folks to go outside run, bike, hike, etc. There's plenty of healthy options that won't put you at risk from contracting the virus.
I don't know where you are, but here in Madrid it's forbidden. Also the gym is closed so it's Netflix + HN.
There are tons of videos on youtube that you can just put on your television and follow along with.
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#67Earlier quoted context omitted.
Masks don’t help for catching the virus (materially) - better to wash hands. Masks do help with curbing transmission from infected, and are also needed for healthcare workers. Please don’t waste masks when you could get significantly better benefit by regularly washing your hands and not putting your fingers in your mouth
If masks curb transmissions. And everyone wore masks. Wouldn't there be a benefit as a whole?
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#68There seems to be a second virus in the west: DMTMW - dont mention the M word - M like mask. Purely looking at the data, the doubling of the infection rate in western countries is between 2-3 days. Looking at Asian countries: Japan: 8-9 days - many people wearing masks Thailand: 10+days - most people wearing masks China: negative values - all people wearing masks (not just in Wuhan) and handsanitizer everywhere Cost…
Masks don’t help for catching the virus (materially) - better to wash hands. Masks do help with curbing transmission from infected, and are also needed for healthcare workers. Please don’t waste masks when you could get significantly better benefit by regularly washing your hands and not putting your fingers in your mouth
Given the distance the virus can travel, the length of time it can live outside the body, how long it can stay in the air after being aerosolized (transmitted via cough). It makes sense to get masks on as many people as possible.. because it's the healthy people who think they are fine, coughing in public places that are the most likely to spread it.
Again, this is assuming supply ramps up and is sufficient to make this a reality, obviously all healthcare worker needs should be met first, but going further to protect the general public should be something to strive for.
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#69Earlier quoted context omitted.
If masks curb transmissions. And everyone wore masks. Wouldn't there be a benefit as a whole?
PMs told that (masks are useless) to people so that doctors can have the masks. In reality masks are insanely effective if everyone wear them.
Also it doesn't make sense to me that "we should leave masks for doctors", as experts and media are saying. The masks sold in the grocery stores and pharmacies are surgical masks.
Surgical masks prevent the wearer from spreading the virus...
Doctors and nurses should have N95 masks, which prevent the wearer from obtaining the virus...
I agree something is better than nothing, but if doctors and nurses are treating infected patients, surgical masks do nothing for them!
In an ideal world, IMHO - we common folks wear surgical masks to contain the spread. Hospital staff wear N95 to prevent them from getting sick.
The sooner we realize this fact - the sooner we can massively produce masks and get people to wear them when going out.
Re: How to fight the coronavirus SARS-CoV-2 and its disease, Covid-19 [pdf]
#70How do we know the doubling time? That seems like the biggest assumption that we're not sure about. I've seen 1 week, 5 days, and even recently 3 days.
The doubling time of deaths appears to be much slower than the doubling time of confirmed cases, and is probably a better comparison. It could be slightly faster than reports, if deaths are getting missed, or misattributed to other illnesses. But it still seems more accurate than judging the doubling time of confirmed cases, which is more just a measure of how quickly we are able to increase testing when there's a ba…
https://commons.wikimedia.org/wiki/File:Log-linear_plot_of_c...