I'm very happy to expand on my thought process. By "epi Twitter" I mean specifically experts I follow, over a wide range of specialties including disaster preparedness, epidemiology, public health, and related topics. These are among the best people in the field, and are kind enough to share with each other and the rest of us their expertise and thoughts through Twitter. It is awe-inspiring to see.
At the same time on Twitter, and at much higher volume, is a torrent of bullshit, with apparently some seeding from active disinformation sources. I try to be very careful to filter this out, though it's not always easy (I find my curation much more effective on desktop web than mobile).
Public health sources are sometimes wrong. For example, Ohio's chief public health doctor put out an estimate of 100k cases on 3/12, propagated through official channels including a tweet from the Governor [1], and which #epi Twitter very quickly criticized. Work out for yourself which to trust; among other things, with the CFR we're seeing, if the public health official is right we'd be seeing approximately 1k excess deaths in OH, with a timeframe that would certainly have started emerging by now.
This particular thing (ibuprofen) is in the category of "emerging research which could be very important if and when it checks out."
So basically I'm trying to be very careful to vet the information I transmit. The pipeline from that to actionable advice can sometimes be infuriatingly slow, which no doubt explains why certain things (especially with an easy-to-understand narrative) jump the queue. I will definitely put this in my resource list as soon as I see trustworthy confirmation. And I am confident that if it actually was valid and important, at least one of the experts I follow would have mentioned it by now.
[1]: https://twitter.com/GovMikeDeWine/status/1238177953126604801