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The neuroinvasive potential of SARS-CoV2

ncbi.nlm.nih.gov

161–170 of 298 posts

Re: The neuroinvasive potential of SARS-CoV2

#161
post #97

Earlier quoted context omitted.

Also is Australia still burning? A burning continent seemed important before the virus, not anymore.

No, I think they switched to flooding now: https://edition.cnn.com/2020/03/03/australia/new-south-wales...

We've got the plague of locusts in Africa, though. Really been a rough half year.

Re: The neuroinvasive potential of SARS-CoV2

#162

Earlier quoted context omitted.

I hardly ever have to deal with anxiety, but now I have a headcold and my coworker sitting 6-feet to my right has a mask on...

You should be the one wearing the mall though no?

Still waiting for mine to be delivered... They're hard to come by!

But I'm sure my coworker is wearing a mask for their own set of reasons...

Re: The neuroinvasive potential of SARS-CoV2

#163
post #95

Earlier quoted context omitted.

https://en.wikipedia.org/wiki/Olfactory_bulb . however: Yan-Chao Li [etal.] ABSTRACT Swine hemagglutinating encephalomyelitis virus (HEV) has been shown to have a capability to propagate via neural circuits to the central nervous system after pe- ripheral inoculation, resulting in acute deadly encepha- lomyelitis in natural host piglets as well as in experimental younger rodents. This study has system- atically exami…

I don't understand what the Wikipedia link is supposed to show. Your eyes are tightly linked to your brain too.

the neuronal terminals leading to a lobe of the brain innervate the nasal mucosa.

the optic nerve is hidden behind the eye with a substantial barrier of non nervous tissue in front of it.

https://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Sc...

Re: The neuroinvasive potential of SARS-CoV2

#164
post #144

Earlier quoted context omitted.

I've seen very different estimates. I'm gonna go off on a limb and say that there's probably more misinformation out there than real information. People should remain calm, take [0]reasonable precautions, and make decisions based on the latest information from credible sources such as the [1]CDC - rather than the media. [0] https://twitter.com/eugenegu/status/1235247642814214145 [1] https://www.cdc.gov/coronavirus/20…

The 40-70% number is from a Harvard Professor of Epidemiology https://www.wsj.com/articles/how-many-people-might-one-perso... > “I think it is likely we’ll see a global pandemic,” said Marc Lipsitch, a professor of epidemiology at Harvard T.H. Chan School of Public Health. “If a pandemic happens, 40% to 70% of people world-wide are likely to be infected in the coming year. What proportion of those will be symptomatic…

"If", then he goes on to give a huge range, and then goes on to say that he can't give even an estimate of what percentage would be symptomatic.

Then, he goes on to give an entirely different range on Twitter, including another statement that he should have said "without effective controls" - https://twitter.com/mlipsitch/status/1234879949946814464?s=2...

So, basically, you proved my point that everyone is so damn eager to talk about this that they'll make claims without sufficient evidence and scare people into distress.

Re: The neuroinvasive potential of SARS-CoV2

#165
post #95

Earlier quoted context omitted.

https://en.wikipedia.org/wiki/Olfactory_bulb . however: Yan-Chao Li [etal.] ABSTRACT Swine hemagglutinating encephalomyelitis virus (HEV) has been shown to have a capability to propagate via neural circuits to the central nervous system after pe- ripheral inoculation, resulting in acute deadly encepha- lomyelitis in natural host piglets as well as in experimental younger rodents. This study has system- atically exami…

I don't understand what the Wikipedia link is supposed to show. Your eyes are tightly linked to your brain too.

yes, but there isn't a direct route from the outside to your brain. Your eye socket is relatively well insulated from the outside by skin, connective tissue, conjunctiva.

Re: The neuroinvasive potential of SARS-CoV2

#166

As a side observation: most reporting seems rather binary, i.e. you either die or survive, period. What interests me the most, however, is how often survival means full recovery, especially now that the nervous system comes up. Are there any long term effects? Should one generally expect to come out of it worse, the same, or stronger? I'm much less afraid to die from this than to end up with chronic respiratory and/o…

It has only been around for a few months so nobody knows. It is also too early to know about reinfection. My advice would be to avoid getting infected if you can but please be mindful that a lot of people won't have the privilege of avoiding it, and they do not need to be unduly stressed from the prospect.

By reinfection they must really be alluding to reanimation

Re: The neuroinvasive potential of SARS-CoV2

#167
post #117

Earlier quoted context omitted.

Cigar smokers FTW...they dont inhale ;)

In that case, it seems like an even weirder affect to take on - none of the nicotine, all of the bad breath and mouth cancer.

Nicotine can be absorbed through the nose and mouth. It's not as effective as through the lungs, but cigars have much higher dosage than cigarettes.

Re: The neuroinvasive potential of SARS-CoV2

#168
post #125

Earlier quoted context omitted.

Yes, only a N95 or better mask would protect you from incoming, as opposed to outgoing, viruses, and these masks are both impractical for everyday wear and need to be conserved for public health users.

Meanwhile in South Korea everyone has masks. In WWII we built one bomber an hour at one plant, and now we can't figure out how to build millions or billions of masks.

That's because that bomber was built by the "greatest" generation. By definition, we aren't the greatest generation.

Re: The neuroinvasive potential of SARS-CoV2

#170
post #10

From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…

>I should also point out that most people in the US face similar conditions to those in Wuhan.

I don't think that's true.

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