Chronic inflammation appears to be caused by persistent self-stimulation -- eating for comfort or pleasure, not getting enough sleep, chain-smoking, getting high, etc, without respite. So it's not really a biological problem. It's a widespread personal problem with complex biological consequences.
Drugs that tamp down inflammation in the brain could slow cognitive decline
31–40 of 80 posts
Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#32From the perspective of a non-biologist reader only seeing popular articles, the past ten years have been completely bewildering. Nutrition has seemingly been boiled down to a couple of magic totems that are always simplistically either good or bad. Antioxidants are good. Inflammation is bad. Telomeres are good. Carbs are bad. All the "bad" things get associated with each other and anti-associated with the good thing…
-> Always been like this.
As a very smart bio professor once said to me: the half-life of a nutrition paper is about 2 years.
Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#33Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#34From the perspective of a non-biologist reader only seeing popular articles, the past ten years have been completely bewildering. Nutrition has seemingly been boiled down to a couple of magic totems that are always simplistically either good or bad. Antioxidants are good. Inflammation is bad. Telomeres are good. Carbs are bad. All the "bad" things get associated with each other and anti-associated with the good thing…
Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#35Chronic inflammation appears to be caused by persistent self-stimulation -- eating for comfort or pleasure, not getting enough sleep, chain-smoking, getting high, etc, without respite. So it's not really a biological problem. It's a widespread personal problem with complex biological consequences.
Can you cite your sources for that claim?
Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#36Wouldn't it be better and more effective to treat the cause of the inflammation instead?
Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#37Chronic inflammation appears to be caused by persistent self-stimulation -- eating for comfort or pleasure, not getting enough sleep, chain-smoking, getting high, etc, without respite. So it's not really a biological problem. It's a widespread personal problem with complex biological consequences.
IMHO, the biggest contributor to chronic inflammation is the Standard American Diet (lots of grains and refined foods) combined with a lack of exercise. These things have a greater, compounding effect with age. You can't exactly tell an 80 year old woman to start running or lift weights on a daily basis.
Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#38Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#39Alternatively, you can quite dramatically reduce inflammation in the brain via some simple lifestyle modifications (cutting out sugar, intermittent fasting): Mattson, Mark P., Keelin Moehl, Nathaniel Ghena, Maggie Schmaedick, and Aiwu Cheng. “Intermittent Metabolic Switching, Neuroplasticity and Brain Health.” Nature Reviews. Neuroscience 19, no. 2 (February 2018): 63–80. https://doi.org/10.1038/nrn.2017.156 . Pinto,…
Re: Drugs that tamp down inflammation in the brain could slow cognitive decline
#40Chronic inflammation appears to be caused by persistent self-stimulation -- eating for comfort or pleasure, not getting enough sleep, chain-smoking, getting high, etc, without respite. So it's not really a biological problem. It's a widespread personal problem with complex biological consequences.
can you expand this concept?
https://twitter.com/DavidDeutschOxf/status/11746303659123261...