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Why Does Inflammation Seem to Underlie All Sickness?

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Re: Why Does Inflammation Seem to Underlie All Sickness?

#71

Post by emmelaich »

huherto wrote: post #43
scns wrote: post #40

Earlier quoted context omitted.

Judo is good for learning to fall, otherwise not that much IMO.

I disagree. I was by far the smallest kid in my grade, but I took a couple of years of judo when I was 7. It was really useful as I grew up. A big equalizer for me. It does give you an intuitive sense of how to move and a shift your weight in your favor. Even if you fall, you end up falling on top of the other kid. As an adult and for personal defense I think Judo comes right after BJJ and wrestling.

Judo definitely helps. Any full contact martial art will, and Judo is the one with the most contact (at kids level) and lowest chance of serious injury. Wrestling too, but Judo typically covers more.

Lots of close contact will mean you're far less likely to panic in a fight situation. Most people have never been in a fight let alone hit.

Plus the fitness of course. Judo helps enormously with core strength.

BJJ borrows a lot from Judo, particularly the grappling.

Re: Why Does Inflammation Seem to Underlie All Sickness?

#72

Post by emmelaich »

programmarchy wrote: post #11
bfieidhbrjr wrote: post #10

Because we pretty much solved all the acute illnesses so we are left with self-inflicted chronic conditions. Pretty much all non-genetic chronic conditions are a result of diet and exercise. You can drastically reduce your chances of cancer, stroke, heart attack, alzeihmers, T2 diabetes, Parkinson’s.... you name it, with diet and exercise. You can even cure most of them with diet and exercise. I’ll be downvoted to ob…

Related to this, I saw an interesting graph where money spent on food is inversely correlated to money spent on health care. So spending more to eat healthier food will save you money on health care in the future. Or you can eat cheap food and accumulate health debt.

One quote I've seen is that the only difference between food and medicine is dosage.

Re: Why Does Inflammation Seem to Underlie All Sickness?

#73

Post by mhluongo »

nitrogen wrote: post #39
mhluongo wrote: post #37

Earlier quoted context omitted.

If you took falling lessons as a kid, and you knew how to properly respond- following the push to a controlled fall, roll, or other redirection- you'd be fine. Sometimes the overreaction is the problem.

What are falling lessons? Judo?

I learned them as "ukemi"- I'm sure judo has them, though I was introduced via karate and later aikido.

Re: Why Does Inflammation Seem to Underlie All Sickness?

#74

Post by darkerside »

derefr wrote: post #21
twic wrote: post #16

Earlier quoted context omitted.

I had never heard of this "cell danger response" before, and there's something about your description that does't smell right to this former cell biologist. It's worth noting that so far, this seems to be a theory being advanced by one scientist: https://www.ncbi.nlm.nih.gov/pubmed/?term=%22cell+danger+res... This is not to say it's not true. But let's be careful here.

The jargon term is https://en.wikipedia.org/wiki/Purinergic_signalling . Personally, I find “Cell Danger Response” useful as a term to specifically reference one type of purinergic signalling. One which, yes, the author you link to is investigating, and invented the “Cell Danger Response” term for; but one which was already known as a type of purinergic signal (and an interesting, unique response to said signal) befo…

Do I understand correctly that sulforaphane could reduce the amount of purines released into the bloodstream? Is it a potential treatment for gout and other hyperuricemia conditions?

Re: Why Does Inflammation Seem to Underlie All Sickness?

#76

Post by libraryatnight »

jniedrauer wrote: post #61

Not all inflammation is bad. Supercompensation can't happen without it. In fact, taking anti-inflammatory substances during training can reduce the efficacy of training[0]. [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023714/

Would this include foods that are naturally anti-inflammatory? Or are those minor in normal/healthy amounts and thus not detrimental to training?

Re: Why Does Inflammation Seem to Underlie All Sickness?

#77

Post by rubicon33 »

woodandsteel wrote: post #69
rubicon33 wrote: post #52

Article is lacking in substance. It's conclusion is basically that there are two types of inflammation - one designed to attack parasites (worms, etc.) the other to attack bacteria and viruses. The theory it proposes is that because humans have basically eradicated parasitic infections, that part of the body becomes over active and leads to autoimmune disorders. 0 link to sources. I've never heard of this "dual infla…

>It's conclusion is basically that there are two types of inflammation - one designed to attack parasites (worms, etc.) the other to attack bacteria and viruses. No, the article doesn't say that. It says there are many types of inflamation, it mentions several types of inflammation including in response to injury,and also autoimmune diseases, and it ends with a discussion of the possibility one of the many reasons in…

I'm just saying that the way the article is written, it comes off as similar to 16th century theory of imbalance of humors [1].

It's just a very surface level explanation, lacking in substance as I said. There's something more concrete going on and this article didn't even attempt to illuminate it.

[1] https://en.wikipedia.org/wiki/Humorism

Re: Why Does Inflammation Seem to Underlie All Sickness?

#79

Post by huffmsa »

manmal wrote: post #56
huffmsa wrote: post #12

Earlier quoted context omitted.

Chronic inflammation worsens chronic illness. Acute inflammation is generally good. Ice should only be applied when the swelling is cutting off blood flow

Ice baths seem to speed up recovery after exercise. But, the mechanisms by which this works are likely not limited to stopping inflammation.

There's actually little research that they do, beyond placebo. It works a lot better in animal trials than with humans. Probably because of differenced in our ability to actively cool ourselves.

https://bjsm.bmj.com/content/46/4/296

Re: Why Does Inflammation Seem to Underlie All Sickness?

#80

Post by pombrand »

bamboozled wrote: post #65
jniedrauer wrote: post #61

Not all inflammation is bad. Supercompensation can't happen without it. In fact, taking anti-inflammatory substances during training can reduce the efficacy of training[0]. [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023714/

Thanks I’ve actually wondered about this for sometime!

It depends, there are several different form of inflammation. Curcumin seems to have little effect on muscle growth post exercise.
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