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Why Does Inflammation Seem to Underlie All Sickness?
51–60 of 86 posts
Re: Why Does Inflammation Seem to Underlie All Sickness?
#52Article is lacking in substance. It's conclusion is basically that there are two types of inflammation - one designed to attack parasites (worms, etc.) the other to attack bacteria and viruses.
The theory it proposes is that because humans have basically eradicated parasitic infections, that part of the body becomes over active and leads to autoimmune disorders.
0 link to sources. I've never heard of this "dual inflammation system". Not saying it's false, just saying, show me the research. Further, show the research that somehow links the under-activity of one to full blown autoimmune disorders. Seems like a weak link.
Re: Why Does Inflammation Seem to Underlie All Sickness?
#53Because we pretty much solved all the acute illnesses so we are left with self-inflicted chronic conditions. Pretty much all non-genetic chronic conditions are a result of diet and exercise. You can drastically reduce your chances of cancer, stroke, heart attack, alzeihmers, T2 diabetes, Parkinson’s.... you name it, with diet and exercise. You can even cure most of them with diet and exercise. I’ll be downvoted to ob…
I know two women who were both marathon runners, and tri-athletes... fit, muscular, well within a healthy BMI... Both developed hashimoto autoimmune disease.
One of the two, eventually also developed more severe autoimmune conditions.
I agree with you that we can prevent a huge amount of disease with diet and exercise. I do not agree with a broad assertion that illness is a choice. That is a cruel misunderstanding of illness, that mocks the people who - despite their best efforts - got a shit roll of the dice.
Re: Why Does Inflammation Seem to Underlie All Sickness?
#54There’s a thing called the “Cell Danger Response”, where individual cells react to detecting danger to themselves in a somewhat selfish way, by inflaming and emitting purines (the chemicals cells also release when they lyse apart during apoptosis.) By the fact that other cells detect danger using these purines, this response is usually cascading in a local area. It lasts a long time; sometimes cells just never go out…
So, is the Cell Danger Response evoked by a certain root condition that cells are suffering from? Like unsufficient ATP production? Have you heard of any theories about that?
Re: Why Does Inflammation Seem to Underlie All Sickness?
#55The article does not really support the implicit thesis from the title - it lists some diseases that are caused by bad inflamation, some items are maybe surprising - but it does not mention diseases that obviously have different causes like infections. Overall clickbait with no content.
Even in infections, it can be the inflammatory response which causes the damage. I had myocarditis following a flu infection, but it wasn't the influenza virus that screwed up my heart muscle, it was the white blood cells going apeshit trying to kill it.
Going into week 2 of the flu (immediately after getting vaccinated...). You've just freaked me out. Time for more research.
Re: Why Does Inflammation Seem to Underlie All Sickness?
#56Earlier quoted context omitted.
Screaming doesn’t worsen stabbing wounds, directly. But inflammation does often (in all the examples I’ve read) worsen the triggering illness.
Chronic inflammation worsens chronic illness. Acute inflammation is generally good. Ice should only be applied when the swelling is cutting off blood flow
Ice baths seem to speed up recovery after exercise. But, the mechanisms by which this works are likely not limited to stopping inflammation.
Re: Why Does Inflammation Seem to Underlie All Sickness?
#57Article is lacking in substance. It's conclusion is basically that there are two types of inflammation - one designed to attack parasites (worms, etc.) the other to attack bacteria and viruses. The theory it proposes is that because humans have basically eradicated parasitic infections, that part of the body becomes over active and leads to autoimmune disorders. 0 link to sources. I've never heard of this "dual infla…
This is all pretty standard textbook immunology. Providing sources would be a bit like citing Newton when mentioning gravity.
In the innate (first responder) system, inflammation is used as a first line of defense (which can also be detrimental), but the mechanism used depends on the target. White blood cells called eosinophils largely respond to macroparasites like worms (although they also play a secondary role in viral infection). Bacteria and fungi are largely dealt with a different cell type, neutrophils, and virus infected cells by natural killer (NK) cells.
https://en.wikipedia.org/wiki/Eosinophil https://en.wikipedia.org/wiki/Neutrophil https://en.wikipedia.org/wiki/Natural_killer_cell
Re: Why Does Inflammation Seem to Underlie All Sickness?
#58Correlation is not causation.
My best understanding is that inflammation is a two street: It both promotes health problems and is, itself, caused by health issues.
Until we have a clearer handle on this dynamic, we are kind of stuck in our current "Jim, don't leave him in the hands of twentieth century medicine!" morass.
Re: Why Does Inflammation Seem to Underlie All Sickness?
#59I see a reference to cancer below, I recently started looking into this, it's actually fascination. There is actually some research being done on non steroidal anti inflammatory drugs such as celecoxib or diclofenac for treatment of leukemia. Since Leukemia is actually related to an increase of white blood cells which are produced in response to inflammation/infection I was curious if there's any relationship and imm…
Re: Why Does Inflammation Seem to Underlie All Sickness?
#60[deleted]