Earlier quoted context omitted.
> 50% of the children will be strictly superior (carriers) Is that domain nomenclature? Because I wouldn't call having to be careful who procreate with otherwise risk losing 25% of my children from that relationship as "strictly superior"...
2/4 resistant to malaria with no side effects and 1/4 dying is much much better than 4/4 dying from malaria
The Fugate family of Kentucky has had blue skin for centuries
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Re: The Fugate family of Kentucky has had blue skin for centuries
#52Is this article a carnival sideshow? " had that caused " I get it, we like to look at situations where people are different, but does this actually inform, educate, or improve us by reading? Or is this article just a chance to point out some people who are different. I've been thinking about this recently, and trying to moderate my curiosity (because blue skin certainly piques my curiosity) against what I'm trying to…
Further, this is an example of a rare genetic disease, of which there are thousands. However, instead of needing an expensive research project to find a cure, a simple off the shelf chemical will do. So if you are ever reading about "Orphan Drugs", you'll also have an example of a successfully treated rare genetic disease!
Re: The Fugate family of Kentucky has had blue skin for centuries
#53Methemoglobinemia seems to be a popular medical topic lately. It's an easily treatable disease, usually methylene blue is used, and it's more an inconvenience than anything else.
Re: The Fugate family of Kentucky has had blue skin for centuries
#54Re: The Fugate family of Kentucky has had blue skin for centuries
#55Earlier quoted context omitted.
2/4 resistant to malaria with no side effects and 1/4 dying is much much better than 4/4 dying from malaria
pretty good considering something like half of all human beings who ever lived died of Malaria!
Re: The Fugate family of Kentucky has had blue skin for centuries
#56Are we going to talk about the absolutely ridiculous amount of ads in this article?
I wonder if someone is spinning me to finally take my driver's license.
Re: The Fugate family of Kentucky has had blue skin for centuries
#57It’s somewhat dishonest to illustrate an article on color with a photo that was colorized by someone we don’t know at an unknow date-- i.e. we don’t know anything about how they decided which shade of blue to apply on their faces. So the only interesting information caried by the photo, the shade of the blue color, has no source.
Also, this appears to be largely copied from this ABC News article: https://abcnews.go.com/Health/blue-skinned-people-kentucky-r...
Re: The Fugate family of Kentucky has had blue skin for centuries
#58A fascinating article, but it's a bit frustrating that there are no colour photos. I tried searching the internet and found photos of other blue-skinned people but none of them had this genetic cause (mostly it was silver "supplements").
https://cdn.mutually.com/wp-content/uploads/2017/10/2-9.jpg
If so, according to the family tree, this would be the last homozygous member of the Fugate family.
Re: The Fugate family of Kentucky has had blue skin for centuries
#59A fascinating article, but it's a bit frustrating that there are no colour photos. I tried searching the internet and found photos of other blue-skinned people but none of them had this genetic cause (mostly it was silver "supplements").
[1] https://abcnews.go.com/Health/internet-sensation-papa-smurf-...
Re: The Fugate family of Kentucky has had blue skin for centuries
#60A fascinating article, but it's a bit frustrating that there are no colour photos. I tried searching the internet and found photos of other blue-skinned people but none of them had this genetic cause (mostly it was silver "supplements").
There's photos out there if you google for "autosomal recessive methemoglobinemia" -- for instance "Papa Smurf" [1] I just think it's super cool if you administer methylene blue dye, they turn back to normal within a half hour. [1] https://abcnews.go.com/Health/internet-sensation-papa-smurf-...
The Fugate family has the methemoglobinemia condition. They can be 'cured' with methylene blue. The former could not.