I suspect if you take away tenure being based upon publication, you will find that many statistical measures become more honest. You can abolish statistical significance, but it won't stop the abuse of knowledge, which is the real problem here anyway.
Could you expand on what you mean by the 'abuse of knowledge'? I agree that the focus on this metric negatively influences research outcomes, which extends to university structuring, but I'd like to hear your thoughts on how this extends to abuse of knowledge in general.
A nice way of saying "lying". Learning how to game the statistics (e.g. publish the 20th experiment that showed significance but fail to mention the other 19).