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Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

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Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#141

Post by jobigoud »

tempsy wrote: post #4

I was heading to the gym near the Twitter HQ in SF yesterday and saw Jack Dorsey walk past. He looked extremely thin and borderline sick to me. I think he does more extended fasts over the weekend but it’s a bit unnerving when someone in a position to influence behavior like he is seems to be taking fasting to an extreme.

Are you sure you are not just used to see slightly overweight people everywhere, and when someone is at the lower end of normal it looks extraordinary to you? I read he is 1.78m tall, that means he could be 59kg (130 lbs) and still be in the normal BMI range.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#142

Post by jobigoud »

crimsonalucard wrote: post #100

If I eat two meals in one sitting and then wait 23 hours before my next meal is this a form of intermittent fasting? I still get the same amount of calories as a normal person but there's a long period where I get nothing. (I've been skipping breakfast my entire life so I don't really get the 3 meal thing.)

Yes, it's known as 23:1 Intermittent Fasting or more commonly OMAD, one meal a day.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#143

Post by [deleted] »

mytailorisrich wrote: post #132
wyclif wrote: post #122

Earlier quoted context omitted.

That also assumes you're getting enough sunlight. A lot of people who work in an office don't.

That's a bad diet compounded by a bad lifestyle. Working in an office does not mean one has to stay indoor all the time and at weekends.

[deleted]

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#144

Post by ubermonkey »

kasey_junk wrote: post #107
ubermonkey wrote: post #79

It's interesting, but as a hobby and primary physical outlet I'm very involved in cycling. I don't race, but I ride with racers, and keep up. I do not think I could balance fasting with 1,500 calorie efforts. ;)

Funny enough in the 70s and 80s (and into the early 90s in some rare cases) it was fairly common for cyclists to cut weight like boxers. I think its fair to assume that caffeine and amphetamines were used to achieve those results and not strict fasting regimes...

Sure. I think that's still done -- I mean, look at top-tier racers.

But fasting and cutting weight are different ideas.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#145

Post by SketchySeaBeast »

dvt wrote: post #94
SketchySeaBeast wrote: post #58

Earlier quoted context omitted.

> I noticed that fasting doesn't help with BF at all unless I eat very clean and lift. So what happens? You lose muscle and fat in the same ratio? Or do you keep the fat?

I feel that my body kind of adjusts to the fasting and I just don't lose much of anything.

That sounds to me like "I eat more to make up the calories when I'm not fasting".

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#146

Post by SketchySeaBeast »

rsync wrote: post #97
SketchySeaBeast wrote: post #91

Earlier quoted context omitted.

> then you never give your body time to do any other housekeeping tasks. Do you have any links to describe what other tasks it would want to be doing in that time and which are blocked by an insulin spike?

https://osher.ucsf.edu/patient-care/integrative-medicine-res... "...it is theorized that cancer cells do not respond to the protective signals generated by fasting, thus leaving them vulnerable to both the immune system and cancer treatment. This process is known as differential stress resistance (DSR). Short-term starvation (STS), fasting for 48 hours, causes a rapid switch of cells to a protected mode, which is cap…

That's not housekeeping though, that's in the case of fighting cancer. And based upon the mechanism you lay out, that's with outside intervention. That doesn't seem to expand out to "general housekeeping" when you're also dealing with medical science trying to kill cancer without killing you.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#147

Post by davinic »

SketchySeaBeast wrote: post #91
rsync wrote: post #68

Earlier quoted context omitted.

"Is there really no difference between eating 1500 calories at once vs. over the course of 5 meals?" Digestion - and the ramping up of your entire metabolic process - is not a minor task. It is an all-hands-on-deck marshaling of a number of bodily processes that preclude other processes that you might like your body to engage in. If you are firing up this mechanism every three hours - insulin response, spiking your b…

> then you never give your body time to do any other housekeeping tasks. Do you have any links to describe what other tasks it would want to be doing in that time and which are blocked by an insulin spike?

Autophagy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990190/

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#148

Post by ulisesrmzroche »

SketchySeaBeast wrote: post #58
dvt wrote: post #46

Earlier quoted context omitted.

I did for a few months this year, but I've been lazy over the summer. I'm 155lb, 6'0, so fairly skinny, maybe at around ~15% BF. I noticed that fasting doesn't help with BF at all unless I eat very clean and lift. I was at 170lb, around ~28% BF earlier this year and had to work my ass off to get my body fat percentage down.

> I noticed that fasting doesn't help with BF at all unless I eat very clean and lift. So what happens? You lose muscle and fat in the same ratio? Or do you keep the fat?

Fat first cus it’s easier to break down. Muscle afterward.

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#149

Post by crimsonalucard »

jobigoud wrote: post #142
crimsonalucard wrote: post #100

If I eat two meals in one sitting and then wait 23 hours before my next meal is this a form of intermittent fasting? I still get the same amount of calories as a normal person but there's a long period where I get nothing. (I've been skipping breakfast my entire life so I don't really get the 3 meal thing.)

Yes, it's known as 23:1 Intermittent Fasting or more commonly OMAD, one meal a day.

Is it? The thing is I'm eating two meals in one sitting so it's still two meals a day. I typically thought intermittent fasting meant one meal per day. Does what I'm doing still count?

Re: Alternate Day Fasting Improves Physiological and Molecular Markers of Aging [pdf]

#150

Post by kasey_junk »

ubermonkey wrote: post #144
kasey_junk wrote: post #107

Earlier quoted context omitted.

Funny enough in the 70s and 80s (and into the early 90s in some rare cases) it was fairly common for cyclists to cut weight like boxers. I think its fair to assume that caffeine and amphetamines were used to achieve those results and not strict fasting regimes...

Sure. I think that's still done -- I mean, look at top-tier racers. But fasting and cutting weight are different ideas.

I just meant that cutting calories while cycle training has a long history (though I would describe it as healthy)
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