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Magnesium and major depression (2011)

ncbi.nlm.nih.gov

191–200 of 235 posts

Re: Magnesium and major depression (2011)

#191
post #85

I started taking magnesium supplements about 9 months ago, not for any depression issues, but more for muscle issues. I had a weird leg muscle injury a few years ago that I never really got a proper diagnosis for that happened when doing some light hiking. In doing my own research on that, a condition similar to my symptoms came up, and one of the causes was a magnesium deficiency. I had a few other minor ailments co…

What kind of Magnesium are you taking? There’s a huge differential of bioavailability of different magnesium types.

I don't have the bottle handy with me, being at work, but I do know I did some basic research on this and its "chelated", not sure what exact type it is beyond that.

Agreed though that bioavailability of any nutritional supplement is always a highly debated topic, I see that the article cites a powdered form, other comments have liquid drops.

Re: Magnesium and major depression (2011)

#192
post #138

Earlier quoted context omitted.

Damn I take tums after every meal and 5 pills of chelated magnesium throughout the day...

Tums after every meal is actually a really good way of getting electrolyte imbalances, to the point of developing kidney stones from the amount that the kidney has to excrete to try and keep things on an even keel. If you need tums after every meal, you should be talking to your doc about a PPI. edit: Now I think on it, actually, depending on (variables), you might need a specialist visit more than a PCP visit for so…

PPIs cause long-term damage, it’s better to try an H2 blocker first.

Re: Magnesium and major depression (2011)

#193

Earlier quoted context omitted.

What kind of Magnesium are you taking? There’s a huge differential of bioavailability of different magnesium types.

People mentioning their experiences here should definitely mention what form they're taking. Magnesium oxide is pretty commonly sold but it doesn't get absorbed very well - to the point where I think it should not be sold at all. I've had good experience with chelated magnesium.

Magnesium biglycinate and Magnesium l-threonate generally have the best effect with the least laxative side-effects (unless you want that); however, l-threonate is quite expensive because of patents, and l-threonate can have (potentially desirable, however potentially dependence building) effects of its own.

One form I haven't tried or researched yet is sucrosomial magnesium, which may have superior bio-availability to both biglycinate and l-threonate with relatively reasonable pricing characteristics.

I personally stopped taking magnesium a little while back, as it seems any bioavailable form pretty reliably causes insomnia for me. YMMV with magnesium, but you gotta make sure you buy it from a reliable source in a good form if you want to give it a proper chance.

Re: Magnesium and major depression (2011)

#194
post #174

Earlier quoted context omitted.

I agree and think these actually enormously overshadow all of the previously mentioned factors except maybe diet. We weren't meant to live out our lives in seas of isolated little poorly ventilated boxes.

Sleeping in a tent for nearly six years actually did my health a world of good. It also dramatically changed my perspective on the state of housing in modern America and its relationship to myriad problems, including health issues, in ways that aren't likely to be taken seriously by most people any time soon. When I comment on such things, it typically gets downvotes and/or snarky, dismissive replies and personal att…

I'd always been dimly aware that I always woke up feeling more refreshed in a tent, but it wasn't until fairly recently that I noticed I got the same effect if I slept with the window open. Now I keep my bedroom window open at all times.

In general, I think society is extremely blase about possible health hazards - if it doesn't kill you instantly, people basically don't wanna know. Alcohol is huge. Smoking is even now considered basically fine by huge swathes of the population. It wasn't until 1996 that leaded gasoline was banned in the US, two decades after lead paint was banned. We tolerate absurd levels of pollution in cities, with not much more than a shrug.

For almost any given product and interaction, you can ask yourself "is there a powerful incentive structure in place to prevent this from invisibly but seriously harming me"? Usually, the answer is "no". It's up to you to pay attention, and ignore what society thinks is okay.

Ancient Romans would consider you a sissy snowflake to avoid their lead pipes - modern society will consider you likewise, if you go out of your way to be healthy. If you don't feel like a sissy snowflake - you're probably being poisoned.

Re: Magnesium and major depression (2011)

#195
post #174

Earlier quoted context omitted.

I agree and think these actually enormously overshadow all of the previously mentioned factors except maybe diet. We weren't meant to live out our lives in seas of isolated little poorly ventilated boxes.

Sleeping in a tent for nearly six years actually did my health a world of good. It also dramatically changed my perspective on the state of housing in modern America and its relationship to myriad problems, including health issues, in ways that aren't likely to be taken seriously by most people any time soon. When I comment on such things, it typically gets downvotes and/or snarky, dismissive replies and personal att…

I'd love to hear more about this! Have you written about your experiences anywhere?

Re: Magnesium and major depression (2011)

#196
post #174

Earlier quoted context omitted.

I agree and think these actually enormously overshadow all of the previously mentioned factors except maybe diet. We weren't meant to live out our lives in seas of isolated little poorly ventilated boxes.

Sleeping in a tent for nearly six years actually did my health a world of good. It also dramatically changed my perspective on the state of housing in modern America and its relationship to myriad problems, including health issues, in ways that aren't likely to be taken seriously by most people any time soon. When I comment on such things, it typically gets downvotes and/or snarky, dismissive replies and personal att…

Hah - when we visit family in the summer, we're lucky to be able to do backyard camping for almost entire stay - reduces stress on the hosts, my young kids love it, and we have a pretty smooth process & kickass tent.

Done it for 4 years now and I can say it does make me feel more alive at the end & there have been minimal sleep incidents.

However, I don't think it's changed the way I share my opinion on housing (perhaps reinforced it?). People get ticked off when you diss their biggest investment even by proxy.

Re: Magnesium and major depression (2011)

#197

The onset of depression has greatly increased in incidence, and it is affecting people much earlier in their lives during the late 20th century and early 21st century than before the 20th century (Meyer and Quenzar, 2005). The reasons for these findings are not quite clear, but inadequate dietary Mg is prevalent in America and is the most likely cause. There is probably a real increase in depression, coupled with a c…

I would wager it's a combination of factors: 1. In general, the north american diet is disgraceful. 2. Consumerism and brainwashing people into believing that they can only be happy when they achieve X, Y or Z, does nothing for people's emotional emptiness. 3. The constant barrage of shit news, most of which is largely irrelevant to most of our lives, most of the time. 4. The constant threat of automation and off-sho…

Something else to consider is that a lot of people live in food deserts, where no nutritional food is available or affordable. People who live in such food deserts often have low incomes, so they really don't have a choice but to have a really awful diet. Richer people tend to have greater, more convenient choices of nutritional food, and the wealth to afford it.

Add to that the fact that many people in the US work insanely long hours in unfulfilling or even demeaning work, little free time to spend with their families, on leisure, or to recover from burnout, possibly mounting medical and credit card bills, little hope for a secure retirement, their children at risk of violence in schools and few prospects when (or if) they graduate. Add in the media which worships wealth, fame, and appearances, and you have almost a sure fire recipe for depression.

It's really a wonder more people aren't depressed.

Re: Magnesium and major depression (2011)

#198
post #190

It feels like internet people legitimately believe dietary changes can cure every single disease sometimes.

Considering how many diseases are caused by lack of, or an excess of specific coumpounds, they are often right. Disease does not always refer to virus/bacteria caused malaides.

Re: Magnesium and major depression (2011)

#199
post #179

Earlier quoted context omitted.

Anecdotical but for years I had various anxiety and mild depression problems (edit: and various muscle “twitches”). As it was not severe I was always recommended Magnesium. Never had any improvement. Then 2 years ago I started taking vitamin D (thanks to HN discussions) and nearly all my symptoms disappeared (also changed job, started meditation, so the datapoint is not clear but magnesium alone didn't do much). Also…

Hello French "brother" Serum levels of vit D and Magnesium are not reliable indicators. As stated in the study for Magnesium. For Vit D, efficiency of a supplementation of Vit D3 is also not on par with real sun exposure, the skin and subcutaneous fat don't seems to respond the same way. I sadly did not had any improvement on my side from getting my Vit D level from 15 (which is barely above the deficiency level) to…

> Serum levels of vit D and Magnesium are not reliable indicators. As stated in the study for Magnesium. For Vit D, efficiency of a supplementation of Vit D3 is also not on par with real sun exposure, the skin and subcutaneous fat don't seems to respond the same way.

Didn't know that, thanks.

> I sadly did not had any improvement on my side from getting my Vit D level from 15 (which is barely above the deficiency level) to a whooping level of 60 in a few month with Bio-D-Mulsion drops (Vit D3)

Given how well my state (physical and mental) noticeably improved these last few months I'm think the main factors were psychological instead of a deficiency (notably getting more financially secure with personal business taking off and going abroad and working remotely). Before that I was already working out and eating well for years, and even if that helped the changes weren't as noticeable. Or maybe it was all of that combined and it just took time to cross a threshold.

Re: Magnesium and major depression (2011)

#200
post #70

I found CBD to provide temporary relief - I think my depression was inflammation related. The world is still dark and compressed but also comfortable, like the dark corners fill with algae and the ground with grass. What ended up working was improving my oral posture and articulation using ortothropics and self-developed speech exercises (the important part is having designed the exercises yourself). Suddenly it's va…

Can you elaborate on oral posture and articulation? I have a major snoring (apnea) and breathing issue due to dentistry mistakes (taking out teeth when I should not have as a kid) and my face caved in which compresses my breathing. This is my theory at least. I am curious because this is the first time I hear about the concepts you brought up

There are basically 2 schools of thought on oral health:

1) The establishment/western orthodontics school where teeth are the root of the problem so are moved around or removed in order to achieve flatness in the face profile. Maintaining results might require wearing a retainer for life.

2) The holistic orthotropic approach where misaligned teeth are a symptom of other issues. It emphasizes myofunctional exercises (for tongue and cheek posture), osteopathic adjustment to realign skull sutures, neck posture and breathing exercises to train the body to regulate its CO2 during sleep. The results are permanent since the patient's efforts help drive bone growth in the palate and changes in the jaw joint.

I sucked my thumb until I was 9 which left me with a severe overbite, then had braces and headgear for 8 years as a child (luckily had no teeth removed) but it left my mouth too small. I am a late bloomer, probably 10 years behind my peers. I began weightlifting in my early 20s and basically have a different body type now than I did in adolescence, so my jaw grew and constricted my throat, which caused sleep apnea for at least 10 years. I've been chronically exhausted most of my adult life and didn't know why. That led to poor self image/self esteem and chronic melancholy/depression although I have never been diagnosed or taken medication for it.

I got fitted with an A.L.F. appliance about 9 months ago and the results have been nothing short of miraculous. I'd say my throat has opened by 1/4 inch or more, my skin has cleared up, my eyebrows have grown back, even my digestive issues have improved dramatically. And to top it off, I just look healthier/happier and feel more attractive in public because I used to have a gummy smile with no teeth visible at the sides and a recessed chin (which are the main causes of babyface).

For anyone reading this, I'd be very wary of orthodontic treatment that requires extractions or headgear. Get a second opinion, and opt for a Herbst device, A.L.F. or D.N.A. appliance instead. Invisiline is fine. Also look on youtube for exercises to improve your jawline, such as chin and tongue frenulum stretches. The most important exercise I've found is to keep your tongue suctioned to the roof of your mouth and learn to swallow with it up like that. The constant pressure of the tip of your tongue above your front teeth causes the nerves to stimulate bone growth to provide room for your top teeth. Then the bottom jaw conforms to the top, which can cause the bottom teeth to spread and straighten as well. But really, find a myofunctional therapist because this is only the tip of the iceberg. You can usually train with them remotely.

My theory for why this is not mainstream knowledge is that there is not as much money in a simple wire and holistic treatment/exercises as there is in orthodontics.

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