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Inflammation might be the root of preventable disease

harvardmagazine.com

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Re: Inflammation might be the root of preventable disease

#221

Post by jodrellblank »

baxtr wrote: post #217
jodrellblank wrote: post #214

Earlier quoted context omitted.

Where do you think did I not address the things I quoted? Quote: "People know what they need to do" - your response to that: ignore it, don't address it. Quote: "that knowledge doesn’t change behavior" - your response to that: ignore knowledge entirely, state that "smarts" changes behaviour. Quote: "Humans are hard-wired to conserve energy (citation)" - your response to that: don't address it, implicitly dismiss it,…

So, you are implying these are my responses even though I never actually wrote them? How is that different from telling me I did not supply citations?

You asked me where I think you didn't address certain points. As you didn't address them, I have no text from you to copy or refer to, I can only point around the area where you didn't talk, to show that it exists.

When you say "work to get smarter instead", that says the problem is a lack of work and a lack of "smart", and therefore that people are ill because they're dumb. It follows from what you said, even though you did not write those words out. So yes, I imply that your responses are your responses.

How is that different from telling me I did not supply citations?

I don't want to read citations, I mentioned them as one example of what "addressing a point" could look like, so that the absence of any of these possible things supports that you didn't address them.

Re: Inflammation might be the root of preventable disease

#222

Post by LinuxBender »

baccheion wrote: post #188
LinuxBender wrote: post #6

In my case, inflammation is a side effect of insulin resistance, like my fellow 83 million Americans with metabolic syndrome. If I can reverse the cause long enough, the liver should stop dumping fat into the adipose tissue and triglycerides may drop.

Vitamin D3 is said to help with metabolic syndrome. Also, intermittent fasting (eating within the same 8-hour window) and keto. Estrogen, DHEA, vitamin K2 MK-4, etc. https://vitamindwiki.com/Overview+Metabolic+Syndrome+and+vit...

I take D3, K2 MK4, K2 MK7, chelated magnesium religiously. For some reason, DHEA doesn't agree with me. I get headaches from it. Excess D3 also causes pain in the back of my head and neck. Curious if its related to calcium scavenging or some deficiency.

Re: Inflammation might be the root of preventable disease

#223

Post by baxtr »

jodrellblank wrote: post #221
baxtr wrote: post #217

Earlier quoted context omitted.

So, you are implying these are my responses even though I never actually wrote them? How is that different from telling me I did not supply citations?

You asked me where I think you didn't address certain points. As you didn't address them, I have no text from you to copy or refer to, I can only point around the area where you didn't talk, to show that it exists. When you say "work to get smarter instead", that says the problem is a lack of work and a lack of "smart", and therefore that people are ill because they're dumb. It follows from what you said, even though…

I asked questions. I never thought about supplying citations when asking questions. I get the feeling you read lots of judgement into my question. My intention was to create a discussion around the question.

Anyway, I guess there is little value in discussing further. Thank you for explaining your reaction. Definitely food for thought

Re: Inflammation might be the root of preventable disease

#224

Post by justinator »

joncrane wrote: post #166
justinator wrote: post #49

Earlier quoted context omitted.

Inflammation can be a signal to the body to heal an area specifically expressing the inflammation. Many treatments involve causing additional damage to the wounded area to promote inflamation. This is good! Its chronic inflammation that's not good.

Isn't this the concept behind dry needling?

I do believe so.

Re: Inflammation might be the root of preventable disease

#225

Post by baccheion »

LinuxBender wrote: post #222
baccheion wrote: post #188

Earlier quoted context omitted.

Vitamin D3 is said to help with metabolic syndrome. Also, intermittent fasting (eating within the same 8-hour window) and keto. Estrogen, DHEA, vitamin K2 MK-4, etc. https://vitamindwiki.com/Overview+Metabolic+Syndrome+and+vit...

I take D3, K2 MK4, K2 MK7, chelated magnesium religiously. For some reason, DHEA doesn't agree with me. I get headaches from it. Excess D3 also causes pain in the back of my head and neck. Curious if its related to calcium scavenging or some deficiency.

How much DHEA did you take and was it with pregnenolone? 5 mg + 5 mg topically is said to be the preferred way to supplement.

The pain may be related to blood pressure.

Is there any reason you didn't also add a multivitamin? How much D and K? Magnesium? Ever had any lab work done?

Re: Inflammation might be the root of preventable disease

#226

Post by LinuxBender »

baccheion wrote: post #225
LinuxBender wrote: post #222

Earlier quoted context omitted.

I take D3, K2 MK4, K2 MK7, chelated magnesium religiously. For some reason, DHEA doesn't agree with me. I get headaches from it. Excess D3 also causes pain in the back of my head and neck. Curious if its related to calcium scavenging or some deficiency.

How much DHEA did you take and was it with pregnenolone? 5 mg + 5 mg topically is said to be the preferred way to supplement. The pain may be related to blood pressure. Is there any reason you didn't also add a multivitamin? How much D and K? Magnesium? Ever had any lab work done?

I also use a multivitamin from time to time, but I get some crappy multivitamins from adv formula slimfast, rainbow-lite and both contain fake vitamins (like ascorbic acid). I try to get most of my vitamins from food.

My BP is under control though I would love to stop using BP drugs. In fact, I would like to see legislation around the use of them, i.e., doctors must within 180 days, find the root causes of the abnormal BP and within 360 days, have the person on a program to fix it. BP drugs are bad news and put people at grave risk (as the body fights the effect) which means if you stop taking them, your body fighting the ffect triggers a rebound. It's happened to me twice when the pharmacy was screwing around with my prescription.

Magnesium is 100mg, 3 times a day. It is chelated and bound to a couple amino acids. K2 MK4, 100mcg twice a day. K2 MK7 100mcg twice a day.

The only lab work I've had done was testing for the usual things, cholesterol, triglycerides, checking for h.pylori, etc... I don't think they even do a ldl lipoprotein spectrum graph.

Re: Inflammation might be the root of preventable disease

#227

Post by LinuxBender »

DoreenMichele wrote: post #97
LinuxBender wrote: post #9

Earlier quoted context omitted.

I did. In fact that was a great start, but once you reach a certain point (in having metabolic syndrome), the Keto+IF reaches diminishing returns. It did bring me down 18 inches on the waist. The gut and hypertension will remain. In fact, my hypertension actually went up. To go further requires either Metformin or Berberine. I opted for Berberine, but time will tell.

Insulin resistance is related to inadequate protein, not excess fat per se. You may need more muscle, which is partly based on getting the right kind and amount of protein. Egg whites are the most bioavailable protein. Humans can use about 98 percent of it. I used egg whites to good effect when one of my sons needed more protein for some reason. Reference: https://news.ycombinator.com/item?id=8748147 (This is not adv…

I eat eggs every day. Also spinach, onions, garlic, broccoli, sometimes wheat grass juice. Most of my protein is low quality soy from adv formula slimfast and I know that isn't great. Whey protein disturbs a wound in my stomach which I am still waiting to have doctors look at.

Re: Inflammation might be the root of preventable disease

#228

Post by LinuxBender »

atomical wrote: post #73
et2o wrote: post #33

Earlier quoted context omitted.

Congratulations on your progress! Interested why you decided against metformin. Lots of people without DM or Metabolic syndrome are taking it for its apparent life extension effects (mostly unproven this far in humans). For diabetes, there's pretty solid evidence. I work in this space tangentially and I had not heard of berberine before. What are you hoping to achieve with this supplement?

Metformin is great if you like shitting your pants constantly. The life extension crowd is going to give us a lot of laughs.

Berberine can do that as well. You have to start off with small doses and let things adjust. I've been doing so many supplements for so long that it didn't really affect me much.

Re: Inflammation might be the root of preventable disease

#229

Post by RobertRoberts »

artemisyna wrote: post #187
RobertRoberts wrote: post #78

Earlier quoted context omitted.

While I don't disagree with the concept of prioritization, that's not the same as cause and effect. Inflammation is an effect that _can_ cause other problems. But as far as I know, inflammation is a symptom of other problems, not a cause in and of itself.

Did you read the article? The article claims that inflammation is both a symptom of other problems (when in reasonable ranges of signalling) and a causer of problems (when signalling too much). I know the title of the article itself is a bit sensationalist, but I would assume that any tests aiming to determine if inflammation is the cause of a problem in specific would also check to make sure that the inflammation wa…

Of course a symptom can cause other problems, this has been addressed in multiple other comments. But suppressing a symptom (inflammation) does not remove the cause of the problem.

fyi:

>Please don't insinuate that someone hasn't read an article. "Did you even read the article? It mentions that" can be shortened to "The article mentions that."

https://news.ycombinator.com/newsguidelines.html

Re: Inflammation might be the root of preventable disease

#230

Post by RobertRoberts »

cududa wrote: post #201
RobertRoberts wrote: post #78

Earlier quoted context omitted.

While I don't disagree with the concept of prioritization, that's not the same as cause and effect. Inflammation is an effect that _can_ cause other problems. But as far as I know, inflammation is a symptom of other problems, not a cause in and of itself.

Your imunorespknse to a modern diet is one example of what triggers a cycle of inflammation. The diet isn’t necessarily good for you, but isn’t inherently bad. A 70,000 year old metabolism treats food the same way it did 70,000 years ago - turning much of the food into fat and surging you with insulin. This is what causes the inflammation. Your body isn’t in an era of scarcity - this response isn’t needed, nor is the…

If the body's response to the current diet in the US (not necessarily in other countries) causes system wide inflammation, then the cause of the damage is diet/food, not inflammation. Inflammation is the symptom, regardless if there are cascading effects, they still start with the root cause.
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