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How to increase serotonin in the human brain without drugs (2007)

ncbi.nlm.nih.gov

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Re: How to increase serotonin in the human brain without drugs (2007)

#81

Post by swozey »

mrpinc wrote: post #22
dekken_ wrote: post #5

More info on niacin/tryptophan https://www.youtube.com/watch?v=yofewUE6L-k https://www.youtube.com/watch?v=-l0S25DIxqw

I took niacin once in pill form and it made my body burst out into a fierce itch rash that lasted about an hour.

This is extremely common with niacin ingestion. If you look up a lot of pre-workout drinks (no xplode for a specific example) it's one of the most common complaints/mentions.

I haven't used it in forever but when I did sort of just got accustomed to being itchy until it wore off. I've read that it can cause liver issues, though. I just quit taking pwo's altogether.

Re: How to increase serotonin in the human brain without drugs (2007)

#82

Post by nbardy »

Kirth wrote: post #60
aantix wrote: post #54

Earlier quoted context omitted.

I wonder if CBD oil raises serotonin? It seems to lift my mood for almost an entire day.

The way CBD interacts with your serotonergic system is very complicated. In short, there are many ways CBD may increase serotonin by activating the serotonin receptors but not causing re-uptake, thus increasing the amount of serotonin in the synapses. CBD is a very interesting substance. My main gripe is that, to get antidepressant and anxiolytic effects, dosages are higher than what can conveniently (and affordably)…

I used CBD for mental health a few years ago to great effect. This company https://hemp-market.eu/hemp-products/ was the only I found that made it affordable. Worth a look.

Re: How to increase serotonin in the human brain without drugs (2007)

#83

Post by DanBC »

asynchronous13 wrote: post #62
DanBC wrote: post #57

People in this thread are repeating the myth that exercise is a treatment for depression, when all the evidence we have shows that it probably isn't. The article links to an old version of the NICE guidance. The new version of that is here: https://www.nice.org.uk/guidance/cg90 It's important to note that exercise isn't being touted as a treatment for depression, but as something that may help people with sub-clinica…

Honestly I feel like you're splitting hairs here. You say that exercise is not a treatment, but at the same time say that exercise may help. Isn't a treatment something that may help? I get it, don't pretend that exercise is the magic pill that will work for everyone, especially for those at the more severe end of the depression spectrum. But, even the NICE guidance that you linked to suggests "taking regular physica…

For clarity: I don't think exercise helps treat depression, unless we're also happy to say that homeopathy treats depression.

Re: How to increase serotonin in the human brain without drugs (2007)

#84

Post by aantix »

Kirth wrote: post #60
aantix wrote: post #54

Earlier quoted context omitted.

I wonder if CBD oil raises serotonin? It seems to lift my mood for almost an entire day.

The way CBD interacts with your serotonergic system is very complicated. In short, there are many ways CBD may increase serotonin by activating the serotonin receptors but not causing re-uptake, thus increasing the amount of serotonin in the synapses. CBD is a very interesting substance. My main gripe is that, to get antidepressant and anxiolytic effects, dosages are higher than what can conveniently (and affordably)…

Agree. It’s easily a $60/mo investment to get a properly tested, refined dosage.

Much more expensive than say a $5/mo Wellbutrin or Lexapro generic.

Re: How to increase serotonin in the human brain without drugs (2007)

#85

Post by an_d_rew »

DanBC wrote: post #57

People in this thread are repeating the myth that exercise is a treatment for depression, when all the evidence we have shows that it probably isn't. The article links to an old version of the NICE guidance. The new version of that is here: https://www.nice.org.uk/guidance/cg90 It's important to note that exercise isn't being touted as a treatment for depression, but as something that may help people with sub-clinica…

> People in this thread are repeating the myth that exercise is a treatment for depression, when all the evidence we have shows that it probably isn't.

Thank you for clearly stating this.

Depression is not "Gee, I've been feeling tired and blue for a couple of days," but it is commonly confused with "short term, mild melancholy".

Depression is a serious illness and needs to be understood and treated as such.

Re: How to increase serotonin in the human brain without drugs (2007)

#88

Post by Beefin »

jw1224 wrote: post #21
Beefin wrote: post #19

Doing my best to summarize the effects of 5-HTP and its' corresponding pubmed research: https://nutripeek.com/detail/5-htp

Do you know anything about how EGCG affects absorption of 5-HTP? I've read in several places that 5-HTP is more effective when consumed with EGCG (green tea extract), but I'm not sure if this is just urban legend or if it has any real–world effects.

Piperine typically increases the bioavailability of most substances, especially fat soluble ones like 5-htp

Re: How to increase serotonin in the human brain without drugs (2007)

#89

Post by uneasy-sausage »

crdrost wrote: post #80
laythea wrote: post #64

Earlier quoted context omitted.

That does beg the interesting question that if you don't feel depressed, are you really depressed?

You are not, on present definitions. This is one of those things that a lot of members of the public at large do not seem to know; they think that depression is defined as some sort of chemical imbalance in the brain, and it is not. Depression is defined in the DSM more or less as, being sad too often, except in cases of mourning etc. where people are often incredibly sad. It is literally defined as an overabundance…

Care to expand on the coping mechanisms you developed? Emotional regulation and stamping out rumination seems to be a wonderful life skill to develop across the entire board.

Re: How to increase serotonin in the human brain without drugs (2007)

#90

Post by wolco »

AWildC182 wrote: post #59
DanBC wrote: post #57

People in this thread are repeating the myth that exercise is a treatment for depression, when all the evidence we have shows that it probably isn't. The article links to an old version of the NICE guidance. The new version of that is here: https://www.nice.org.uk/guidance/cg90 It's important to note that exercise isn't being touted as a treatment for depression, but as something that may help people with sub-clinica…

Yea, I think people are confusing the effects of exercise in different cases. IMO there are really at least two groups here: A) >= moderately athletic people with above average health and can sustain strenuous cardiovascular activity. For these people going out and exercising is a form of self actualization which IME is a pretty hard counter to depression. It's an "easy" way of being very good at something and that g…

It's about increasing pxygen / body flow and increasing the body's detoxification process.
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