Engineering is all about making trade-offs (“perfect is the enemy of the good and all”) and security engineering is no different. The same logic could be used to say that you don't need an edge firewall because each client should have one but it's much easier to simplify the baseline.
If nothing else, it would make the remaining traffic stand out more since you wouldn't be spending time auditing normal apps which decode cleanly and it's highly likely that someone trying to circumvent such a system would be required to do things which stand out more than routine usage.
As a simple example, an organization which does that kind of monitoring is unlikely to allow users to install arbitrary applications or visit any site on the web. With a standard setup, someone trying to exfiltrate data could just hit a popular site like Github, Gmail, Dropbox, etc. but if they need to use some custom encryption or steganography code they're either forced to install it somewhere far less common (i.e. more likely to stand out) or installing something locally where client monitoring can report an unusual browser extension or application.