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Consumption of a dark roast coffee blend reduces DNA damage in humans

ncbi.nlm.nih.gov

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Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#151

Post by _Schizotypy »

SubiculumCode wrote: post #97
tachyonbeam wrote: post #19

Earlier quoted context omitted.

I'm generally sceptical of all studies about coffee for this very reason. There's a lot of bullshit studies around food and supplements funded with people with strongly vested interests in selling more product. It's a real problem. For any given supplement, you can often find multiple studies supporting its use and multiple studies saying it's harmful. When it comes to coffee specifically, if you listen to the studie…

Roasting aka burning the beans seems like it would be a cause of cancer, similar to research about cancer causing agents in the burnt aspects of meat, etc.

I think the cancerous agents in burnt meat are caused by extremely high temps, higher than would be reached in coffee roasting. High temps in coffee roasting could cause the undesirable effect of caffeine break down.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#152

Post by coldtea »

AstralStorm wrote: post #141
coldtea wrote: post #127

Earlier quoted context omitted.

> We should expect and welcome research with the awareness of vested interests. No, we should ban vested interests from funding research studies and reduce the SnR.

You mean push them into second order vested interest funding?

No, I mean harsh criminals penalties if they can be connected to higher-order vested interest funding too...

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#153

Post by atorodius »

brenfrow wrote: post #75

I wonder if they took fast vs slow metabolizers into account. It seems to be healthy only with the fast metabolizers gene: https://drwillcole.com/caffeine-one-thing-standing-optimal-h... If you’re a slow caffeine metabolizer: 1. Increased risk of high blood pressure (hypertension). 2. Increased risk of heart attack. 3. Higher chance of digestive disorders. 4. More stress and measurable cortisol spikes. If you're a fa…

I'm a bit confused by the linked article. The only link to a study I found was to [1] published Advances in Psychiatric Treatment. The other study quoted is for some specific effects the article mentions. Any idea where the link between CYP1A2 and caffein comes from?

[1] https://www.cambridge.org/core/journals/advances-in-psychiat...

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#154

Post by sxiin »

flyGuyOnTheSly wrote: post #42

Stopped drinking coffee months ago and I have never felt better. Anxiety is down. Sleeplessness is down. General mood is up. Best of all, I no longer get headaches due to Caffeine withdrawal.

Well, I quit drinking coffee 3 years ago and I can confirm all this. Before quitting I drank approximately 3 mugs of coffee per day.

Withdrawal symptoms for me were a really bad migraine for one whole week and that actually made my final decision to never start drinking coffee casually again.

However, as I try to avoid all kinds of absolutism, I enjoyed a small cup of campfire coffee last autumn.

For some reason drinking tea doesn't make me anxious or tense.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#155

Post by hnnh44 »

tome wrote: post #149
hnnh44 wrote: post #140

Earlier quoted context omitted.

This is funny. Just a while back there was an article posted about how studies SHOULD start out with defined objectives. The argument was that academics are so desperate to publish positive results that they'll draw any positive conclusion, even if it wasn't what the study started out trying to accomplish.

Indeed. What you are describing is p-hacking https://en.wikipedia.org/wiki/Data_dredging

Thank you! I didn't know there was a term for it.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#156

Post by kawfey »

sxiin wrote: post #154
flyGuyOnTheSly wrote: post #42

Stopped drinking coffee months ago and I have never felt better. Anxiety is down. Sleeplessness is down. General mood is up. Best of all, I no longer get headaches due to Caffeine withdrawal.

Well, I quit drinking coffee 3 years ago and I can confirm all this. Before quitting I drank approximately 3 mugs of coffee per day. Withdrawal symptoms for me were a really bad migraine for one whole week and that actually made my final decision to never start drinking coffee casually again. However, as I try to avoid all kinds of absolutism, I enjoyed a small cup of campfire coffee last autumn. For some reason drin…

I like to believe the calmness from tea comes from L-theanine, commonly present in tea leaves. https://en.wikipedia.org/wiki/Theanine

However, experimenting with putting theanine in coffee and consuming energy drinks with caffeine+theanine aren't as relaxing, perhaps because of the higher caffeine content, or other relaxing compounds in tea.

I drank about 40oz of coffee a day, and had the same symptoms if I stopped. I started replacing coffee with tea and the symptoms were a lot less severe. I'm now down to about 1c a day of coffee I grind and brew myself, as if it's a hobby enjoying the flavors and characteristics of different beans/grinds/brewing methods, not because I need caffeine to be a functional adult.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#157

Post by lousyd »

coldtea wrote: post #127
stevenhuang wrote: post #108

Earlier quoted context omitted.

> you can often find multiple studies supporting its use and multiple studies saying it's harmful. While true and I get your point, there isn't anything inherently wrong with that. We should expect and welcome research with the awareness of vested interests. Afterall it's not surprising for a substance to be beneficial in certain ways yet harmful in other ways. Research from opposing groups will help identify all int…

> We should expect and welcome research with the awareness of vested interests. No, we should ban vested interests from funding research studies and reduce the SnR.

Who could possibly not be a vested interest? It's hard to think of more than a few cases where I've personally wanted to learn about something and didn't, at some level, hope for one answer or outcome over another. "Ban vested interests" is an impractical policy. stevenhuang's suggestion to be aware of them is much more practical and has the benefit that "vested interests" who truly do wish to fund an objective study aren't stopped from doing so.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#158

Post by flyGuyOnTheSly »

pedroaraujo wrote: post #143
flyGuyOnTheSly wrote: post #42

Stopped drinking coffee months ago and I have never felt better. Anxiety is down. Sleeplessness is down. General mood is up. Best of all, I no longer get headaches due to Caffeine withdrawal.

The problem with these type of comments is that they never mention how much coffee, and what type of coffee, was consumed before the life-changing decision. It is pretty much anecdotal evidence.

Agreed, it is anecdotal.

But for the record, I drank about 500ml of coffee per day. About a full single french press container.

I certainly drank a lot less than most people who swear that they felt fine drinking 5x as much as that per day... with some even claiming that drinking it just before bed helped them sleep.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#159

Post by flyGuyOnTheSly »

rimliu wrote: post #123
flyGuyOnTheSly wrote: post #42

Stopped drinking coffee months ago and I have never felt better. Anxiety is down. Sleeplessness is down. General mood is up. Best of all, I no longer get headaches due to Caffeine withdrawal.

Was quitting coffee the only change you've made in your lifestyle? Or did you e.g. started working out, be more strict about your daily regime, be more careful with what you eat?

It was the largest single change, yes.

I have always eaten healthy food, I go for walks and hikes and bike rides regularly but I wouldn't say that I "work out".

I just developed a massive headache one afternoon, realized it was because I hadn't had my morning cup of joe, felt disgusted with myself as a result, and decided to quit drinking it altogether.

I figure that anything as addictive as that has no place being consumed daily.

I grew out of my nicotine habits and other addictive drug habits years ago for the exact same reasons.

Re: Consumption of a dark roast coffee blend reduces DNA damage in humans

#160

Post by kempbellt »

nabla9 wrote: post #66
kempbellt wrote: post #61

Yeah, this is bullshit. 100 people were a part of this "controlled" study. Please don't be one of those people that runs around telling people this. This is nothing more than biased surveying by a weak company in attempt to create self-promoting propaganda. Thank you @1_over_n for doing the research

100 people can be enough. Single number like N is not going to tell much. People should learn the basics of statistics before they start to have opinions.

In what world would 100 people be enough to represent anything accurately enough to make a generalized claim like this? All I know from the article is that there were 50 women and 50 men involved. It says nothing of age, fitness, dietary regimen, etc. Based on the "statistics" provided, I could equally make the claim that "drinking a warm drink reduces DNA damage".

Also, please don't generalize "people" in your backhanded comment. I recommend that you study up on critical reasoning. Maybe then you would come to understanding that most "statistics" are unintentionally (or intentionally) biased, and are therefore bullshit, and not to be taken at face value.

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