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Compass Pathways has set itself up to be the first legal provider of psilocybin

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Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#121

Post by ddoolin »

achileas wrote: post #111
pbhjpbhj wrote: post #105

Earlier quoted context omitted.

Only one study on psilocybin? Globally? Ever? That's kinda amazing; not even studies in v long-term [mental] health of [former] users? Edit: Google Scholar shows hundreds of studies, one on the first page (for me) has >700 citations.

On humans using regular consumption? Such research is notoriously hard to get funding and materials for - much easier on animal models, in the US at least. There's a reason much of the current research (which is still too little) into psychedelics is done outside the US.

Can the U.S. (or companies/groups/organizations) within use those outside studies to justify things like this? Or is there some requirement that they be conducted here?

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#122

Post by drb91 »

y-c-o-m-b wrote: post #15
drb91 wrote: post #4

I must say I take a huge amount of joy watching a corporation try to bend over backwards to monopolize a fungus that has been enjoyed by humans for millenia. Is it a surprise that a capitalist industry is more motivated by profits than by the production of useful goods and services? Of course not: but it is good comedy. Maybe laughing at the absurdity of for-profit healthcare will be what saves us all from crippling…

The article says they are trying to restrict how research on the drug is done too and that's a catastrophe on its own. No laughing matter here. This might seem ridiculous on the surface, but it's a sinister move.

If you can’t laugh at the news, you’ll cry. Sanity is important.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#124

Post by kristofferR »

bdamm wrote: post #83
ada1981 wrote: post #66

Earlier quoted context omitted.

What people seem to miss is that it’s the psychedelic experience itself that holds the healing potential. We most likely won’t see a pill derived from mushrooms that cures depression but doesn’t get you high. The altered state of conciousness is the thing.

Unclear. I have close family that is having marked and unprecedented success in treating serious depression by microdosing psilocybin below the psychedelic threshold. The result is profound, sustained, and after trying a dozen different approved psychiatrist prescribed drugs to find help can not be a placebo effect as surely any of those would have been just as effective.

There isn't a clear threshold in regards to microdosing. You're still getting the psychedelic effect from the psilocybin, just proportionally less.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#125

Post by rdiddly »

jjeaff wrote: post #117
rdiddly wrote: post #106

Earlier quoted context omitted.

You can spin it any way you want, but to me, expropriating the intellectual property of the non-profit (obtained under the pretense of being a non-profit) and exploiting it for private gain is the issue here. Even though that part is apparently legal. (Unless challenged in court somehow. We'll see.)

Isn't exploiting the intellectual property of a non-profit for financial gain the business model for essentially every single tech company in existence? That is, at least every tech company that has open source software somewhere in their stack - which is presumably all of them.

Touché, and you could argue that every big success story from the last couple centuries was based on exploiting some kind of freebie. (I'm thinking of the Rockefellers, Carnegies, and Vanderbilts of the world.) Although there are some OSS licenses that address this by restricting commercial uses more heavily. I dunno... if everyone goes into it with eyes open, that seems fine to me. It's when they pull the ol' bait-and-switch that makes me go hmmmm...

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#126

Post by Matticus_Rex »

waynecochran wrote: post #112
jcoffland wrote: post #98

Earlier quoted context omitted.

Not to mention Amanita Ocreata or A. Phalloides.

That is why I never eat mushrooms that rely on my ability to identify them.

I do it all the time, though I avoid a few that have poisonous lookalikes. I picked some oyster mushrooms on the way home from the grocery store today in the middle of town. Even a child can safely identify a number of great edible mushrooms.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#127

Post by Matticus_Rex »

elcomet wrote: post #25
perfmode wrote: post #22

Earlier quoted context omitted.

this isn’t an addictive substance. Edit: the OP removed statement about addiction

I removed the addictive part. This substance can have dangerous side-effects and bring you to the hospital, so it doesn't need to be addictive to hurt yourself.

What exactly are the dangerous side-effects of psilocybin? Yes, you shouldn't drive or make big decisions while on it, but that's not hard to control for (and is similar to many OTC medicines). What are the side-effects that are sending you to the hospital?

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#128

Post by ogoldhill »

pbhjpbhj wrote: post #105
ogoldhill wrote: post #41

Earlier quoted context omitted.

At the moment, there's nowhere near enough research yet to know the potential downsides of using psilocybin to treat depression. So far, there's only been one study with 19 participants and no control group. It could be hugely successful or, as with any drug, it could come with possible side effects.

Only one study on psilocybin? Globally? Ever? That's kinda amazing; not even studies in v long-term [mental] health of [former] users? Edit: Google Scholar shows hundreds of studies, one on the first page (for me) has >700 citations.

One study on psilocybin as a treatment for depression! Not on psilocybin overall. Link to the one existing study is in my article.

Re: Compass Pathways has set itself up to be the first legal provider of psilocybin

#130

Post by [deleted] »

alexibm wrote: post #107
basseq wrote: post #35

This is an interesting article for HN. It's spun as a negative, using terms like "threatening", "monopoly", "controversial", and "retribution". You could write it the other way, where an immigrant-founded[1] startup is disrupting the mental health industry. Frankly, most of this seems like par for the course. Of course the company is seeking to push their product to market and commercial viability--and the potential…

I'm so tired of comments like "startup is disrupting the [xyz] industry." No they don't disrupting anything. They didn't invent anything. They are just planning to grow and sell mushrooms. Growing mushrooms is well know process.

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