I have yet to encounter anything that can match the sheer flexibility of Emacs. For example I am currently using Org mode to write some documentation complete with hyper-links, tables, foot notes and the option to export the results as LaTeX, HTML, Open-Office, and so on with just a few keypresses. It's not just an editor, or an IDE, or even a windowing system - it is a cross-platform computing environment that can b…
Emacs is an OS that lacks a decent text editor (the joke is as old as Emacs).
GuixSD is nicely integrated but Emacs Guile port is not "official" and "mature" enough to have it really as a sole OS, also GuixSD use bash by default, not Emacs at login...
For now I'm happy enough with NixOS+EXWM despite few annoyance not directly caused by Emacs :-)