That heavily depends on where you're operating from. Ignoring the latency problems of using Hetzner et al. for a moment (if you're based on the US). Increasingly as the Internet fractures down lines of very distinctly separate legal structures nation to nation (or region to region), Hetzner, OVH and Scaleway are not going to be viable choices for most organizations in the US. Particularly as it pertains to production environments and until or unless they get proper US facilities.
If I physically operate in the US and I base my servers in the EU, then I open myself up to not only US but also EU jurisdiction and compliance in a myriad of ways. It's an entirely unnecesary additional burden in exchange for a discount on infrastructure (which is rarely the biggest cost in anything these days).
I have no intention of ever complying with GDPR for example, unless I'm running a very large organization. Not because I disagree with most of GDPR, rather, because I'm going to comply with US laws, as that's my legal jurisdiction and those are the laws I'm governed by.
Hosting with Scaleway, OVH or Hetzner is a big jurisdiction mistake in most cases for smaller US organizations, just as it would be to arbitrarily host in Japan or China or Brazil (ie foreign locales with entirely different laws).