CBD is a CB1 receptor antagonist, which means it suppresses activity in those receptors which are found in the brain and the tissues of other organs throughout the entire body. Excess CB1 activity seems to be implicated in many different disorders (most notably obesity).
Chronic CB1 receptor antagonism is associated with:
- lowered blood pressure
- increased levels of Akkermensia bacteria in the gut (associated with leanness)
- decreased lipogenesis (creation of new fat cells)
- decreased fat masss
- resistance to obesity, despite caloric surplus
- increased fatty acid oxidation
- increased adiponectin
- increased transdifferentiation of white fat into metabolically active brown fat
- increased insulin sensitivity
- reduced insulin levels
- increased leptin sensitivity
- reduced proteinurea and improved creatinine clearance in kidney disease
- smoking and cocaine cessation
- reduction in depression symptoms
- reduced anxiety
Search PubMed for "CB1 antagonist" or "chronic CB1 blockade" to see what kinds of things CB1 antagonism can do. You'll find quite a lot of research into Rimonabant (another CB1 antagonist) but unfortunately it was found to cause psychological side effects like depression and suicidal ideation; CBD does not have these effects.
There are several anecdotal reports the on /r/cbd subreddit where people start taking it for anxiety and depression, and end up losing 10-40 lbs. of excess weight without trying.
I've found that it helps me sleep deeply, helps me focus at work, and I am satiated after much smaller amounts of food than before. I also notice that I can run at a significantly higher intensity on the treadmill for much longer with CBD.
I have recommended CBD to 7 or 8 people, and each one reports a plethora of benefits: helps depression, anxiety, ADHD, sleep, weight loss, brain fog, overeating, etc.
There seems to be a good amount of variety in the quality of non-isolate CBD products. Some contain minute amounts of THC and other psychoactive cannabinoids, so they may cause you to fail a drug test if that's a concern.
CBD is one incredibly beneficial compound. I highly recommend you try it if it's available where you live.