Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

'Unique' cannabis compound reverses brain aging in mice

dw.com

Post reply on HN
Print view View original

91–100 of 101 posts

Re: 'Unique' cannabis compound reverses brain aging in mice

#91

Post by folkrav »

adriand wrote: post #30
Erlich_Bachman wrote: post #19

Earlier quoted context omitted.

The point is that the panic attack is most likely not due to the substance itself, but due to how you used it. The experience of others shows that it's possible to use it and not get panic attacks, even if that was the original reaction.

I don't agree with this, even though it's a common opinion. There is something about the combination of cannabis and certain people (their mental makeup? their neurophysiology?) which either inevitably, or randomly, leads to poor outcomes from consuming even very small amounts of cannabis even under ideal conditions. If you know yourself well enough to understand a substance is not for you, then the solution is simpl…

To play Devil's advocate, you don't really know if it's really about one's physiology or just how you used it. I had two consecutive panic attacks back when I was 18 that led to me completely stopping for years before I tried it again years later in smaller doses, and I haven't had panic attacks since. Been smoking occasionally for about 5-6 now.

Re: 'Unique' cannabis compound reverses brain aging in mice

#92

Post by jackric »

Angostura wrote: post #59
jackric wrote: post #8

Earlier quoted context omitted.

My experience is not lowered thinking abilities, but different thinking abilities. If you conceptualize thinking as traversing a graph of thoughts, 'uppers' enhance depth-first traversal, THC enhances breadth-first traversal. This can be a useful mode for generating ideas.

> My experience is not lowered thinking abilities, but different thinking abilities. And when I'm drunk I become an incredibly good singer. ... of course the people around me, strongly disagree. But I know better. Might it be the same with your 'different' thinking?

Yes, if I was waffling on about how like, socialism could totally work man.

But I'm talking about: - coming up with recursive solutions in software for simplicity gains - noticing and fixing inefficient item placement in my kitchen - understanding a conflict from the other person's perspective, to reduce my tension

Re: 'Unique' cannabis compound reverses brain aging in mice

#93

Post by pmoriarty »

utexaspunk wrote: post #88
wholinator2 wrote: post #64

Earlier quoted context omitted.

I used to agree that marijuana wasn't an addictive substance. And within the same post you state it is nonaddictive, you go on to state all the addictive properties of it. I think it is dangerous and wrong for people to tell everyone that marijuana isn't addictive. It would certainly like for you to think so though. Obligatory, everybody's bodies are different, what works for you might not work for everyone, ymmv, et…

Eh, addiction usually implies a physiological reaction to withdrawal. AFAIK it's pretty well established that there is no physical addiction to cannabis. One can very easily feel dependent upon it, though. Then again, if I were to cut off my Wellbutrin or Vyvanse cold turkey I'd be in for a rough ride as well. The fact that something can be habit-forming does not necessarily make it bad.

There are two types of addiction: physiological and psychological.

The kind you get physical withdrawal symptoms from are physiologically addictive. These are drugs like alcohol, nicotine, and heroin.

Cannabis can be psychologically addictive. You can crave it when you stop or have trouble coping with life without it -- much like people who are psychologically addicted to eating lots of food. Both are psychologically addictive.

You can get psychologically addicted to just about anything pleasurable or desirable. I try not to do that with cannabis or anything else.

Re: 'Unique' cannabis compound reverses brain aging in mice

#94

Post by thefounder »

kaybe wrote: post #75
thefounder wrote: post #62

Earlier quoted context omitted.

We still don't have flying cars....so I would't bet that much on the tech progress. Maybe in 100+ years we will get something close but I doubt we will discover immortality any time soon.

It's called a helicopter. Turns out it's very impractical and wasteful for everyday use.

The helicopter is not a flying car. I was expecting something more like this[0]. Of course, who thought we would run on disel with cheating software?

http://3.bp.blogspot.com/-9vdTTtte1Og/UN-rVHj9yEI/AAAAAAACSa...

Re: 'Unique' cannabis compound reverses brain aging in mice

#95

Post by atomical »

acct1771 wrote: post #69
toomanybeersies wrote: post #17

Earlier quoted context omitted.

I've always enjoyed any of the above substances (except opiates) specifically because they lower your thinking abilities. Sometimes it's nice to get fucked up and give your brain an even off from over-analysing everything. Of course, drinking, smoking, or snorting your problems away isn't a good idea. That's how you form a habit. But if you're in a good frame of mind, it's nice to lose your shit every once in a while…

It's also pretty dangerous. Ketamine is very valuable, but not to be trifled with, reader.

Ketamine is one of the safest, cheapest drugs on the market. It is even used on babies because it doesn't suppress respiration.

Re: 'Unique' cannabis compound reverses brain aging in mice

#96

Post by shafyy »

cup-of-tea wrote: post #90
pmoriarty wrote: post #9

Earlier quoted context omitted.

You're most likely overdosing -- something that's very easy to accidentally do with the crazy strong pot out there these days. It's even easier to overdose for newbies who have basically no tolerance and often mistakenly think they have to smoke a full joint (or even just a full big puff of some strong pot) to get high. That's probably way, way too much. If you are willing to give it another chance, you could try fin…

Louis CK has a great story about smoking strong weed [0]. It is really insane how strong some stuff is now. In the UK people used to refer to skunk, but now anything you get is even stronger than skunk. But that's what happens in an unregulated market with potentially dangerous products. [0] https://youtube.com/watch?v=U8FzGlgVGdo

I used to love Louis CK, but after that that whole thing came out about him that he's fucking creep I can't even get myself to watch 1 min of his videos anymore. WHY LOUIS, WHY?!

Re: 'Unique' cannabis compound reverses brain aging in mice

#97

Post by Erlich_Bachman »

[deleted] wrote: post #24

[deleted]

BTW, you can achieve this permanently with deep spiritual work and most importantly, meditation.

Shinzen Young talks about the different experiments they are now starting to perform with deep practitioners of Zen Buddhism (but other schools can likely achieve the same effect). In one of them they are measuring a certain specific response in the brain, which for a normal person happens when they hear a new unexpected stimuli, like a sudden loud bird chirp outside. For a normal person, if this same stimuli is repeated, the "novelty" response in the brain dampens after 2-3 repetitions, and each subsequent chirp is not registering in their brain in the same way. For them it becomes something old. But when they measure a meditating practitioner in the same way - they exhibit the novelty response unlimited number of times, each time a chirp is played. It is like each time it happens - for them it's like a completely new experience.

Re: 'Unique' cannabis compound reverses brain aging in mice

#98

Post by gr__or »

jackric wrote: post #8
ssijak wrote: post #5

I just don't like anything with 'stoned' effect. Pot, too much alcohol, ketamine.. I can`t find the point in being stoned or to lower my thinking capabilities. Stronger opiates I would never ever try because there is no point besides running away from some problem that should be confronted. With the help of psychedelics maybe? :)

My experience is not lowered thinking abilities, but different thinking abilities. If you conceptualize thinking as traversing a graph of thoughts, 'uppers' enhance depth-first traversal, THC enhances breadth-first traversal. This can be a useful mode for generating ideas.

Ha, that's exactly how I describe it to people!

And with psychedelics you can traverse the graph upwards, deconstructing all branches you pass on your way.

Re: 'Unique' cannabis compound reverses brain aging in mice

#99

Post by cup-of-tea »

shafyy wrote: post #96
cup-of-tea wrote: post #90

Earlier quoted context omitted.

Louis CK has a great story about smoking strong weed [0]. It is really insane how strong some stuff is now. In the UK people used to refer to skunk, but now anything you get is even stronger than skunk. But that's what happens in an unregulated market with potentially dangerous products. [0] https://youtube.com/watch?v=U8FzGlgVGdo

I used to love Louis CK, but after that that whole thing came out about him that he's fucking creep I can't even get myself to watch 1 min of his videos anymore. WHY LOUIS, WHY?!

What thing?

Re: 'Unique' cannabis compound reverses brain aging in mice

#100

Post by mnm1 »

Broken_Hippo wrote: post #37
pmoriarty wrote: post #12

Earlier quoted context omitted.

I feel it enhances my creativity, makes me appreciate the world around me more, makes music and food more enjoyable, makes movies more interesting, makes me more interested in doing something artistic or musical and be more involved in doing those things when I do them. Sex can also be amazing on it. When I've used it, I've also confronted things, thought about things, and remembered things I would have avoided in or…

I'm pretty sure that pot is not an addictive substance. Quitting pot is easier than quitting caffeine. Heavy smokers sober up quite often for job drug tests, for example. I've personally smoked for years and just quit for a while. Some things get a little off because of habit changing: A few days of decreased appetite and a bit of insomnia. The hardest part is dealing with the boredom I get at first. I simply don't w…

> I'm pretty sure that pot is not an addictive substance.

That's exactly what they said about coke. You're wrong. If it's not an addictive substance, this is news to me. It's about half way through the year and I've probably tried to quit about 90 times or roughly every other day. It most certainly is addictive in every sense of the word and even has mild physical withdrawal symptoms. Yes, it's not like withdrawing from heroin, and it probably won't make one sell everything to get it, but to say it's not addictive is simply false. I'm not against daily use and I'm not saying it's necessarily negative, but it most certainly is addictive for some people. As the Luniz song goes, "THC ain't no joke."

Post reply on HN