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Caffeine dosing strategies to optimize alertness during sleep loss

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Re: Caffeine dosing strategies to optimize alertness during sleep loss

#133
post #3

Personal anecdata, I was drinking several cups of coffee to get myself through 7 hours' driving with a full work day spliced within. I used to feel absolutely dreadful. Why am I so tired despite drinking all this coffee? I used to think. I then started limiting myself to one small coffee a day. Bingo, all symptoms gone. The coffee was making me feel far worse than I would otherwise have done as it wore off, I believe…

It's alertness effects go away after repeated use and subsequent tolerance building. The best way to use it is in moderation: decaf or no caffeine some days, caffeine other days when it is needed. Drinking it daily is common and often done out of liking/habit/addiction or some combination of those. However, the best positive effects will be seen with moderation.

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#134

I drink about a gallon of caffeinated drinks a day, sometimes more. Am I the only one? I don't have problems sleeping, headaches, or with fatigue. I look forward to the jitters; it actually cheers me up to know that soon I'll be so intense.

~ 25% Caucasians are fast metabolisers of caffeine so can expect to not notice much of a change with standard doses. Doesn’t mean it isn’t doing it’s thing on a biochemical level (both reuptake of intracellular adenosine and driving tolerance)

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#135
post #8

I drink a lot of tea. About 1 liter a day as a baseline, but if I do some ultrahike or something I can easily drink 3 liters a day. Sometimes for some reason it's really hard to drink my tea (e.g. I'm in a hotel that doesn't have drinkable tea), so I tried to substitute with other caffeine products. Unfortunately I couldn't find out any reliable data on the caffeine content of the tea that I drink. All the informatio…

Where can I get/try good tea? Order online? Any recommendations?

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#136
post #34

Earlier quoted context omitted.

Wow, this is actually a thing! I thought it was just me. As someone who used to drink a LOT of cola-cola during their teens, caffeine really fucked me up good. I only noticed I was dependant (addicted) on caffeine after a friend pointed out I only felt good again on certain days after coming back from a client where there was no cola available. I took a little bottle with me to the client and felt "normal" that day.…

I regularly stop drinking caffeine for days at a time and have been unable to notice a difference. It's a shame because I was really hoping to find that my headaches had an easy solution like not drinking caffeine, but they don't appear to be correlated.

I find it necessary to stop caffeine for 14+ days before I get to experience improved energy levels. For about 1-2 days i feel really tired after discontinuing coffee, then for the next couple weeks I feel OK but not as good as when I was drinking coffee. After a couple weeks I start feeling like I have more energy than when I’m drinking coffee daily.

I still choose to drink coffee just because I love the taste and the ritual so much. I limit myself to 1 cup in the morning daily.

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#137
Genetics play an important factor. CYP1A2, one of the enzymes that metabolizes caffeine, varies by as much as 40x between individuals.

In those with a high level of the enzyme, caffeine is metabolized quickly, so they can drink coffee in the afternoon and still fall asleep. They are less likely to get anxiety from caffeine, and do not suffer from a higher risk of heart attacks with coffee consumption.

In contrast, a small amount of CYPA12 prevents caffeine from being metabolized and prolongs its effects.

[0] https://en.wikipedia.org/wiki/CYP1A2

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#138

Club mate is the drink of choice in the start up community in Berlin. I've made the mistake of drinking that in the evening a couple of times and regretted that at 4am by being wide awake and unproductive the next day. If you are not familiar, mate tea which this is based on contains a form of caffeine that is particularly potent. It's like drinking multiple espresso shots. Don't drink this if you have blood pressure…

When you get headaches, chances are you are dehydrated. I would suggest to drink a lot of water before and after drinking coffee or when you feel pain in your head. Drinking a lot of water works for me many times while enjoying too much caffeine in my body.

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#139

Surely there’s a better drug than coffee for staying awake for a long time.

An organic wild blueberry + strawberry smoothie (no other ingredients). But that's not the point - you shouldn't stay awake for too long of a time in the first place.

Re: Caffeine dosing strategies to optimize alertness during sleep loss

#140

I drink about a gallon of caffeinated drinks a day, sometimes more. Am I the only one? I don't have problems sleeping, headaches, or with fatigue. I look forward to the jitters; it actually cheers me up to know that soon I'll be so intense.

Are you the only one? No.

Will that habit do long term damage to your physical, emotional, mental, and professional health? Absolutely.

It's so common and acceptable to be physically addicted to a stimulant (caffeine) that people tend to forget they are indeed physically addicted to a stimulant. Not saying I haven't been there in the past... but wouldn't you view your habit differently if 'I'm not alive before my second cup of coffee, hehe!' was replaced with 'I need a bump of cocaine to start my day'?

I'm not implying that cocaine and caffeine are equally harmful drugs, just pointing out that physical dependence on a stimulant is NOT healthy, even if it's the norm.

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