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Cancer ‘vaccine’ eliminates tumors in mice

med.stanford.edu

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Re: Cancer ‘vaccine’ eliminates tumors in mice

#81

Post by trott »

mbag wrote: post #27
perlgeek wrote: post #15

This seems to be the actual paper: http://stm.sciencemag.org/content/10/426/eaan4488 I hope this translates well to humans and other mammals.

I see that authors are from Stanford University. Can someone from the US clarify if this will be in public domain/knowledge, or is it possible some drug company will patent this later on?

> that authors are from Stanford University. Can someone from the US clarify if this will be in public domain/knowledge

This type of research tends to be publicly funded. However, that doesn't prevent it from being privately patented because of the https://en.wikipedia.org/wiki/Bayh-Dole_Act

Re: Cancer ‘vaccine’ eliminates tumors in mice

#82

Post by cup-of-tea »

Obviously not as important as the main cause but I wonder if a similar thing could be used to treat warts. I had a wart once and successfully got rid of it by applying a trick I read on the internet which is putting a little square of duct tape on it. Surprisingly it really worked. The Wikipedia page used to list the method with dubious citations and said that one theory for why it worked was that the duct tape stimulated the immune system and caused it to attack the wart when it normally wouldn't.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#83

Post by kkartik »

jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

Sorry to know of your situation. If you want to learn more about a trial in this space (currently enrolling) let me know, I can help.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#84

Post by kkartik »

mark212 wrote: post #67
jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

My wife and I are about one year ahead of you with the same diagnosis, currently fighting a recurrence. Keep fighting, stay positive. (And yes the science is astounding and rapidly developing.)

Replied earlier, same to you. ---- Sorry to know of your situation. If you want to learn more about a trial in this space (currently enrolling) let me know, I can help.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#85

Post by nsxwolf »

jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

A different monoclonal antibody treatment successfully treated my grandfather’s lymphoma 10 years ago. It had spread to occupy large portions of his lungs and this treatment was nothing short of miraculous. We watched in awe as the tumors shrunk away.

I hope it works as well for her.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#86

Post by bitwize »

jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

Hope your wife pulls through. Shit's gotta be rough.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#87

Post by jcims »

kkartik wrote: post #83
jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

Sorry to know of your situation. If you want to learn more about a trial in this space (currently enrolling) let me know, I can help.

Always interested in learning our options, thank you!

Re: Cancer ‘vaccine’ eliminates tumors in mice

#88

Post by rgejman »

danieltillett wrote: post #40
rplnt wrote: post #34

Earlier quoted context omitted.

> If some drug company doesn't pick this up it will fall by the wayside and never make it to market. This isn't mutually exclusive to the treatment being in the public domain.

Drug companies don't pick up treatments that are in the public domain. No patent, no pay.

This is just not true. Drug companies will make slight modifications to existing drugs and can get new patents on the new formulations and for new indications. If it works, a drug company can make money off of it even if it's been off-patent for years. See https://en.wikipedia.org/wiki/Lenalidomide vs thalidomide for an example.

For every therapeutic target there are many chemical/biological solutions that can work. If an off-patent compound shows some effect in a pathway, a patentable variant can usually be made.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#89

Post by WilliamSt »

jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

If you haven't already, read: Tripping Over the Truth: The Return of the Metabolic Theory of Cancer Illuminates a New and Hopeful Path to a Cure (ISBN: 9781603587303). It is a great review of the history of Cancer. It concludes that the reason for the failed war against cancer stems from a flawed paradigm that categorizes cancer as an exclusively genetic disease and explores therapies born from the emerging metabolic theory of cancer.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#90

Post by baldfat »

jcims wrote: post #76
baldfat wrote: post #66

Earlier quoted context omitted.

So sorry to hear your story. Cancer just plan old sucks. It has impacted my family and one of my adopted children. My mom had pancreatic cancer (The deadliest of cancers) in 2017 and she is absolutely fine and cancer free a year later. Numbers don't mean anything to the individual and don't look them up is always my recommendation. As a non-medically trained support member I have gotten pretty good in talking with th…

Wow. Based on the small bit of experience I've had so far it's clear you have been down this road. Thank you so much for the advice, it's getting stowed away for future reference.

If you ever want to contact me my email is in my profile. If I could help in any non-medical questions or advice even just a little bit it would be my pleasure.
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