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Cancer ‘vaccine’ eliminates tumors in mice

med.stanford.edu

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Re: Cancer ‘vaccine’ eliminates tumors in mice

#21

Post by allenz »

King-Aaron wrote: post #16
allenz wrote: post #14

Earlier quoted context omitted.

It is indeed a cancer treatment that needs a tumor to work. The authors call their technique "in situ vaccination" because it stimulates antibodies against that specific cancer, which can work throughout the body to destroy metastases.

Cool, thanks for your reply (and those replies below also). I briefly skimmed the article however was sidetracked with work, and admittedly a lot went over my head anyway.

The article is really nicely written. I'd be happy to answer any questions about it.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#22

Post by [deleted] »

Odenwaelder wrote: post #9

We see similar effects when we irradiate tumors with X-rays, called 'abscopal effect'. Sometimes, when you irradiate a tumor, the unirradiated metastases also shrink. It is hypothesized that the immune response is triggered by the irradiation, and there are currently studies being done that try to stimulate the immune system even more. What I wonder is why this is being discovered only now.

[deleted]

Re: Cancer ‘vaccine’ eliminates tumors in mice

#26

Post by dazc »

allenz wrote: post #21
King-Aaron wrote: post #16

Earlier quoted context omitted.

Cool, thanks for your reply (and those replies below also). I briefly skimmed the article however was sidetracked with work, and admittedly a lot went over my head anyway.

The article is really nicely written. I'd be happy to answer any questions about it.

As a regular man in the street, how excited should I be about this?

What's the chance of this developing into a regular treatment for most types of cancers, within, say, the next ten years?

Re: Cancer ‘vaccine’ eliminates tumors in mice

#27

Post by mbag »

perlgeek wrote: post #15

This seems to be the actual paper: http://stm.sciencemag.org/content/10/426/eaan4488 I hope this translates well to humans and other mammals.

I see that authors are from Stanford University. Can someone from the US clarify if this will be in public domain/knowledge, or is it possible some drug company will patent this later on?

Re: Cancer ‘vaccine’ eliminates tumors in mice

#28

Post by [deleted] »

0wing wrote: post #13
Odenwaelder wrote: post #9

We see similar effects when we irradiate tumors with X-rays, called 'abscopal effect'. Sometimes, when you irradiate a tumor, the unirradiated metastases also shrink. It is hypothesized that the immune response is triggered by the irradiation, and there are currently studies being done that try to stimulate the immune system even more. What I wonder is why this is being discovered only now.

Yes but can it be done with minimal side effect? Curing cancer with a bullet works too but the host suffers some adverse side effects.

[deleted]

Re: Cancer ‘vaccine’ eliminates tumors in mice

#29

Post by Iv »

Odenwaelder wrote: post #18
0wing wrote: post #13

Earlier quoted context omitted.

Yes but can it be done with minimal side effect? Curing cancer with a bullet works too but the host suffers some adverse side effects.

I'd be careful calling the immune approach easy. Triggering a systemic immune response can also kill you very quickly.

Considering that chemotherapy is basically feeding poison to your organism in the hope that cancer cells (which are more active) will ingest it in higher quantity, I'd say that we have a pretty high tolerance threshold in term of side-effects while we are looking for an alternative.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#30

Post by dmichulke »

Odenwaelder wrote: post #18
0wing wrote: post #13

Earlier quoted context omitted.

Yes but can it be done with minimal side effect? Curing cancer with a bullet works too but the host suffers some adverse side effects.

I'd be careful calling the immune approach easy. Triggering a systemic immune response can also kill you very quickly.

I think the name for this is

https://en.wikipedia.org/wiki/Cytokine_storm

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