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Cancer ‘vaccine’ eliminates tumors in mice

med.stanford.edu

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Re: Cancer ‘vaccine’ eliminates tumors in mice

#71

Post by jonloldrup »

chiefalchemist wrote: post #70
jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

My thoughts and prayers to your wife, you, and your families. My question is: if we boost the immune system, what are the side effects? Is an immune system that's compromised (e.g., loses battle with cancer) indicative of other problems? In other words, in a way, is cancer actually a symptom? Good luck. And God's speed.

As to the side effects of immune activation, here's a long article on that: https://healthcareinamerica.us/did-chinese-scientists-find-a...

Re: Cancer ‘vaccine’ eliminates tumors in mice

#72

Post by shadowtree »

If they’re at mice this is, at best, 10 years away from getting approved for humans.

Immuno-Oncology is the hot new shit, a huge wave of biotech startups is betting everything on it.

Celgene bought Juno for 11bn recently, Gilead bought Kite for 12bn.

Puts tech startups into perspective :) Tres commas...

Re: Cancer ‘vaccine’ eliminates tumors in mice

#75

Post by jcims »

mark212 wrote: post #67
jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

My wife and I are about one year ahead of you with the same diagnosis, currently fighting a recurrence. Keep fighting, stay positive. (And yes the science is astounding and rapidly developing.)

Thank you brother. Best wishes to you and yours as well, may you come out the other side even stronger in your relationship to each other and your collective resolve to squeeze every drop out of this life we've been graced.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#76

Post by jcims »

baldfat wrote: post #66
jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

So sorry to hear your story. Cancer just plan old sucks. It has impacted my family and one of my adopted children. My mom had pancreatic cancer (The deadliest of cancers) in 2017 and she is absolutely fine and cancer free a year later. Numbers don't mean anything to the individual and don't look them up is always my recommendation. As a non-medically trained support member I have gotten pretty good in talking with th…

Wow. Based on the small bit of experience I've had so far it's clear you have been down this road. Thank you so much for the advice, it's getting stowed away for future reference.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#77

Post by hwillis »

jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

Squeeze her hand for a stranger. Every person who has lost someone to cancer, and everyone who has survived it, and all of the people who watched that fight- all of us have her back and stand with her. She's fighting one of the hardest battles put to a person, and she has our respect and awe. I saw my friend at his weakest, and also when he was stronger than anyone I've ever known. It's been years but still, I'm crying. Cancer is personal. Once it touches you, and you see the enemy, you see how everyone is fighting your enemy. I'm grateful to her. We'll be cheering when the bell rings for her- all of us.

Fuck cancer.

Re: Cancer ‘vaccine’ eliminates tumors in mice

#78

Post by josu »

shadowtree wrote: post #72

If they’re at mice this is, at best, 10 years away from getting approved for humans. Immuno-Oncology is the hot new shit, a huge wave of biotech startups is betting everything on it. Celgene bought Juno for 11bn recently, Gilead bought Kite for 12bn. Puts tech startups into perspective :) Tres commas...

>10 years away from getting approved for humans.

Isn't there a fast-track for experimental treatments for late stage cancer?

Re: Cancer ‘vaccine’ eliminates tumors in mice

#79

Post by pharaohgeek »

jcims wrote: post #55

Writing this from a squeaky recliner set beside my wife’s bed in the oncology department of a local research hospital. Three weeks ago she had a radical hysterectomy and partial lymphadenectomy to treat stage IIIc ovarian cancer, and we’re back to try to aid her in her recovery to prepare for chemotherapy. Chemo should start next week, but we are hoping to also participate in a clinical trial for atezolizumab. This i…

Cancer is a horrible disease. And the current treatments are barbaric. As someone who just finished chemo a year ago, I can't wait for treatments like this to become effective and more mainstream. Best of luck to your wife, and tell her to stay strong!

Re: Cancer ‘vaccine’ eliminates tumors in mice

#80

Post by sjg007 »

mbag wrote: post #27
perlgeek wrote: post #15

This seems to be the actual paper: http://stm.sciencemag.org/content/10/426/eaan4488 I hope this translates well to humans and other mammals.

I see that authors are from Stanford University. Can someone from the US clarify if this will be in public domain/knowledge, or is it possible some drug company will patent this later on?

One drug is already FDA approved. They have a clinical trial for lymphoma. Stanford may patent many parts of it, the two drug combo.. depends on the novelty and the formulation, how it's delivered. It also depends on how obvious it is in the patent sense. You might find other researchers and companies who optimize the system as well (e.g. fine tune the checkpoint inhibitor). But these drugs are manufactured already. So it seems safe to say that the research will be done and if it works we will see clinical use.

Also by definition a patent is in the pubic domain (for knowledge) and the publication is of course a public disclosure.

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