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Two genes in Chromosomes 13 and 14, linked to Homosexuality

nature.com

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Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#51
post #30
post #4

I suspect that as we come to better understand genetics, we (as a society) are going to be more and more uncomfortable with the findings that we uncover. Physics and mathematics have made it long since clear that the universe is deterministic, that all the answers lie in the genes and atoms and equations we are made up of. The implications of this are dire - our society is built on exactly the opposite foundations; l…

Physics gave up being "deterministic" (in the sense you used the term in) about 120 years ago. And mathematics is just a convenient tool with which we describe reality, no one would seriously think today that our math is deeply inscribed in the essence of reality as Galileo thought. Apart from this, and the fact that the paper shows a very weak statistical significance, I agree fully with your last statement.

Reality is just a convenient tool with which we can discern mathematics.

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#52
post #27
post #12

Earlier quoted context omitted.

> Physics and mathematics have made it long since clear that the universe is deterministic Except none of them have any idea whats really going on...

We know a lot of things. We simply focus all of our effort on the things we do not yet understand.

Not according to Thomas Kuhn, we don't.

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#53
post #50

Earlier quoted context omitted.

> Your genes might predispose you towards one path or another, but there is still free will involved. Genetic determinism is not the same as free will. Our genes don't determine everything, but together with our environment, they do.

They don't determine everything is my point. Environment paired with genetics has a strong (sometimes overwhelming) influence on the decisions you make for sure, and they make many decisions harder or easier, but you still maintain the ability to choose. Free will isn't the ability to make any choice without external influences, it's just that you have a choice at all.

What are you calling a choice? Are you simply saying that people act? Then yes, that's of course tautologically true.

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#54
post #39

Earlier quoted context omitted.

> Physics and mathematics have made it long since clear that the universe is deterministic Have they?

Sure, John Calvin told us so. And then we rejected it. And then it became a sure thing again. And then not . . . and now here we are.

Can the universe be deterministic if our knowledge of whether the universe is deterministic is not deterministic?

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#55
post #32

Earlier quoted context omitted.

It's interesting how the timing has an effect on the ethical implications as well. If we had this technology 50 years ago it would be a clear cut case of selecting the straight genes only. This discovery coming now means that the debate could go the other way (no interfering). Much of the world is also less friendly to homosexuality, to put it lightly. I wonder if they will eliminate it entirely?

The countries that could afford this type of intervention are typically much more friendly than the countries that could not afford this.

For now. Some genetics costs are decreasing faster than exponential: https://www.genome.gov/27541954/dna-sequencing-costs-data/

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#56
post #4

I suspect that as we come to better understand genetics, we (as a society) are going to be more and more uncomfortable with the findings that we uncover. Physics and mathematics have made it long since clear that the universe is deterministic, that all the answers lie in the genes and atoms and equations we are made up of. The implications of this are dire - our society is built on exactly the opposite foundations; l…

> law and order assumes the criminals are acting of free will, education assumes all students are equal, and societal success rests on the notion that all men are equal None of this is true. We would still imprison those who break the law, despite a deterministic universe, for quarantine, if nothing else.

We punish for dissuasion. Some who would break the law in the absence of punishment will "choose" (however one wants to interpret that word in a fully deterministic world) not to do so because of the possibility and cost of punishment.

Even punishments such as fines still make sense in a fully deterministic world, and in one where there is no societal desire to be "fair" or give people what they "deserve".

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#57
post #5

Wow, the bioethical implications of potentially identifying the mechanism of sexual orientation are staggering. I wonder if / how long it will be before parents have the technical means—if not the legal right—to alter their child to be gay or straight through gene therapy. Or even simply selectively bring to term one orientation or the other.

In reading your comment I was struck by the dilemma that this reality would bring. Those most opposed to homosexuality are those most opposed to terminating pregnancy (mostly). It would create quite a quandary for folks who are inclined to hold these two beliefs.

Cognitive dissonance is alive and well. (edit - spelling)

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#58
post #50

Earlier quoted context omitted.

They don't determine everything is my point. Environment paired with genetics has a strong (sometimes overwhelming) influence on the decisions you make for sure, and they make many decisions harder or easier, but you still maintain the ability to choose. Free will isn't the ability to make any choice without external influences, it's just that you have a choice at all.

What are you calling a choice? Are you simply saying that people act? Then yes, that's of course tautologically true.

I think we just have an unbridgeable gap of beliefs here: one of you believes that they are the ultimate author of their own words and actions, that their experience of making decisions should be taken as strong evidence that they are in fact making decisions, and that any theory that denied this fact would be in need of revision. The other believes that the scientific enterprise has conclusively disproven the possibility of actual free will, and therefore agency is merely an illusion.

Lately I’ve been siding with the first stance, but I can understand both. It comes down to the strength of your faith that Science understands (for the most part) all of the essential features of reality, and also your trust in your immediate experience.

It’s a tough question.

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#59
post #6

Earlier quoted context omitted.

This is the most important statement in the paper.

Let's pretend I don't have a PhD and don't know what that statement means though, can I get a summary?

This may help: https://en.wikipedia.org/wiki/Genome-wide_association_study

They found "support" for associations between homosexuality and some specific genetic code positions, but not strong enough evidence to be very sure of anything ("significance").

Re: Two genes in Chromosomes 13 and 14, linked to Homosexuality

#60
post #5

Wow, the bioethical implications of potentially identifying the mechanism of sexual orientation are staggering. I wonder if / how long it will be before parents have the technical means—if not the legal right—to alter their child to be gay or straight through gene therapy. Or even simply selectively bring to term one orientation or the other.

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