While the focus is on the original business case for building Mega planes like the A380 the knock-on/hidden impact of closing the A380 line has detrimental impact on Airports that invested millions into being 'A380 ready'.
Airports around the world spent millions of dollars building out A380 capable terminal gates, wider taxi-ways and bigger baggage handling systems to deal with A380 arrivals and departures. Food caterers invested money in special trucks that deliver food to the upper deck. At the ATC level, slots and flight seperation guidelines were changed to accomodate the whale jets. Some airports were chastised for not investing fast enough (ORD?, SEA) to be A380 ready. I guess they now look wiser. The death of the A380 will reduce risk taking by airports in the future.
Failed aircraft projects have a large negative impact on future appetite for these crafts. Just look at what happened to supersonic flight. We have not seen any commercial investment and research into supersonic air travel. While the case can be easily made against these white elephant projects, the knock on R&D benefits of these airlines projects are amazing.
Selective R&D 'Hand of God' moments that allow government support could be the solution here. At minimum, it would be great if China, Japan or any other aspiring aerospace super powers can buy the project and invest in its future.