This reminds me of trophic cascades and e.g the unintuitive link that killing wolfs affects riverbeds: https://shadowproof.com/2014/02/20/trophic-cascade-how-wolve... It like we can't understand complex systems very well. Almost everything we do seem to have to have major unintended consequences. We see this over and over again, we have to abandon the "as cheap and fast as possible" thinking !
I'd reckon the geniuses in the labs do understand complex systems very well, only problem is that these chemists, engineers, etc who do bring concerns their concerns to the table tend to get shut down in favor of getting a product to market so that the company can continue to reap profits no matter what the environmental impact.