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Ketamine lifts rodents' mood only if administered by male researchers

nature.com

241–250 of 258 posts

Re: Ketamine lifts rodents' mood only if administered by male researchers

#241
post #144

Why does the article mention ketamine as a club drug? It's a terrible drug for clubs if anything.

Strongly disagree. Speed and Ketamine in combination is probably the greatest time you'll ever have.

Lying on the floor of a club curled up drooling all over yourself in a dissociated state doesn't sound very appealing to me. I'd keep that for controllable environments.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#242
post #3

Before anyone who didn't actually read the link goes off at it - this is a peer reviewed, repeated study - mice react to drugs differently depending on the sex of the researcher, don't in a fume hood, do always in a fume hood with a human male's t-shirt. It potentially plays havoc with ALL past experiments with rodents ...

Its already known that past experiments with rodents are problematic. A number of studies could not be repeated, and it took a while before they twigged that it was the higher proportion of female scientists. The rationale in the article I read was that the rats were more stressed when the males were around, and disguising the smell mitigated it like they found in this new study.

Another similar problem was mice in maze experiments, which also could not be repeated. The experimenters were using mazes with sand on the floor rather than hard bases, and it turned out that the earlier experiments were not measuring the memories of mice; instead their ability to sense vibrations from their footsteps and helped with location senses.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#243

Earlier quoted context omitted.

Are you actually implying that my making a joke is evidence of some deep dark secret about my sexuality?

Since you ask: it's not just me, it's science (also journalism documenting many recent and historic events) that says many homophobes are secretly gay, and it's also a popular and widely known trope and basis of many memes, which you should take into account next time you feel the irresistible urge make a homophobic joke without intending for people to assume you're a closeted gay. Rule of thumb: If you're really not…

I don't really want to respond to this wall of text. I can't even bring myself to read the the whole thing. Except I want to point out that I don't care what anybody on here thinks about my sexuality. I really don't. How could I? None of this is about -me- because nobody on here knows the slightest bit of detail about my personal life.

I just had a thought that I (and evidently at least one other person) found humorous, and I felt a desire to share, nothing nobler or less noble. I was utterly shocked that it prompted a flame war that came to the attention of the mods.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#244
post #106
post #91

Earlier quoted context omitted.

So rats have a built in gene sequencer and detect the base pairs directly?

Your friend's eye color is defined by some genes. You don't need a gene sequencer to see what they are.

Right, but wehat you detect is the eye colour, not the genes that cause it. Similarly with the rats they detect the pheromones in a male's smell, not the XY chromosomes. So suggesting they detect the XY chromosomes isn't helpful.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#245

Earlier quoted context omitted.

Since you ask: it's not just me, it's science (also journalism documenting many recent and historic events) that says many homophobes are secretly gay, and it's also a popular and widely known trope and basis of many memes, which you should take into account next time you feel the irresistible urge make a homophobic joke without intending for people to assume you're a closeted gay. Rule of thumb: If you're really not…

I don't really want to respond to this wall of text. I can't even bring myself to read the the whole thing. Except I want to point out that I don't care what anybody on here thinks about my sexuality. I really don't. How could I? None of this is about -me- because nobody on here knows the slightest bit of detail about my personal life. I just had a thought that I (and evidently at least one other person) found humoro…

Then I hope you learned something: Stop telling homophobic jokes if you have a problem with people thinking you're gay, or even if you don't. Got it? Have any problem with that?

Re: Ketamine lifts rodents' mood only if administered by male researchers

#246

Earlier quoted context omitted.

I don't really want to respond to this wall of text. I can't even bring myself to read the the whole thing. Except I want to point out that I don't care what anybody on here thinks about my sexuality. I really don't. How could I? None of this is about -me- because nobody on here knows the slightest bit of detail about my personal life. I just had a thought that I (and evidently at least one other person) found humoro…

Then I hope you learned something: Stop telling homophobic jokes if you have a problem with people thinking you're gay, or even if you don't. Got it? Have any problem with that?

i) Nothing about the joke is homophobic.

ii) I learned something, but perhaps not what you wish I'd learned.

iii) I don't care if you think I'm gay, partly because I wouldn't care if I were gay or not, but mostly because I don't care what strangers think at all.

iv) My jokes are no more or less funny depending on the sexuality of the teller.

v) I generally don't have any problem with anything anybody thinks or says, though political winds in other countries are starting to concern me a bit, Canada's pronoun law for example. So long as we're only talking and nobody's going to jail for wrongspeak, I think there's no problem.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#247
post #88

Earlier quoted context omitted.

How?

If the shirt contains 50 chemicals, try each of them in isolation. For starters.

That's what they do on CSI, but that's not how it works in real life. I'm not a chemical engineer, so I can't explain why this doesn't work, but I've proposed this approach and various variations on it to some engineers for other purposes and got all sorts of explanations why it wouldn't work which I didn't understand; but the underlying concept was that you can't just take a sample of whatever and deconstruct and reconstruct it at will.

Re: Ketamine lifts rodents' mood only if administered by male researchers

#248

Earlier quoted context omitted.

Then I hope you learned something: Stop telling homophobic jokes if you have a problem with people thinking you're gay, or even if you don't. Got it? Have any problem with that?

i) Nothing about the joke is homophobic. ii) I learned something, but perhaps not what you wish I'd learned. iii) I don't care if you think I'm gay, partly because I wouldn't care if I were gay or not, but mostly because I don't care what strangers think at all. iv) My jokes are no more or less funny depending on the sexuality of the teller. v) I generally don't have any problem with anything anybody thinks or says,…

1) That's not what most people thought, which is why you were immediately downvoted, flagged, and rightfully called an ass.

2) Stop making homophobic jokes and then pretending they're not homophobic, if you don't want people to know you're an asshole.

3) You've already revealed a lot of personal information about yourself and your character in this discussion and your comment history.

So do you agree to stop telling homophobic jokes, or not? If not, then why do you insist on violating the rules of this community by telling them?

Re: Ketamine lifts rodents' mood only if administered by male researchers

#249

Earlier quoted context omitted.

Is that intellectually honest, to hide from the truth you know about your food?

I struggled with this. I suppose it's not intellectually honest, but I learned intellectual honesty is not my highest priority.

That explains your intellectually dishonest statement that "Nothing about the joke is homophobic."

https://news.ycombinator.com/item?id=15764612

Re: Ketamine lifts rodents' mood only if administered by male researchers

#250
post #247

Earlier quoted context omitted.

If the shirt contains 50 chemicals, try each of them in isolation. For starters.

That's what they do on CSI, but that's not how it works in real life. I'm not a chemical engineer, so I can't explain why this doesn't work, but I've proposed this approach and various variations on it to some engineers for other purposes and got all sorts of explanations why it wouldn't work which I didn't understand; but the underlying concept was that you can't just take a sample of whatever and deconstruct and re…

> you can't just take a sample of whatever and deconstruct and reconstruct it at will

This is fairly generally true in science. Deconstructionism was a fever dream.

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