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A big, successful trial of probiotics

theatlantic.com

11–20 of 70 posts

Re: A big, successful trial of probiotics

#11

The 9% placebo and even the 5% treatment sepsis rate seems very high. According to http://emedicine.medscape.com/article/978352-overview#a6 the US rate of neonatal sepsis is around 2/1000 live births so around 0.2%. Given this, I wonder how applicable these results would be to neonates in the US.

It may be that because of diet or other factors, this just wouldn't be as useful in the US.

Re: A big, successful trial of probiotics

#12
post #3

Here's the nature article (paywall): http://www.nature.com/nature/journal/vaop/ncurrent/full/natu... "The special mixture included a probiotic called Lactobacillus plantarum ATCC-202195 combined with fructo-oligosaccharide (FOS), an oral synbiotic preparation developed by Dr. Panigrahi." (from https://medicalxpress.com/news/2017-08-probiotics-sepsis-inf... ) Decrease in other infections (respiratory and nasal) is par…

Problem solved http://sci-hub.io/10.1038/nature23480

Spasiba Russia.

Re: A big, successful trial of probiotics

#13

All the products containing Lactobacillus plantarum may see a boost in sales.

are there any though? From the article, it seems that they had to cultivate the colonies themselves.

Many brewers actually use lacto P to sour beer quickly. It's cheap and widely available.

Re: A big, successful trial of probiotics

#14

All the products containing Lactobacillus plantarum may see a boost in sales.

When my son was born I did a bunch is research on probiotics with good scientific evidence of efficacy. I ended up getting him these which contain most of the promising/researched strains. It's also a liquid which helps in giving it to a baby. I'm pretty convinced that a good probiotic and Onega3 supliment are extremely beneficial.

https://www.amazon.com/BIOAMICUS-COMPLETE-Toddler-Probiotic-...

Re: A big, successful trial of probiotics

#15

The 9% placebo and even the 5% treatment sepsis rate seems very high. According to http://emedicine.medscape.com/article/978352-overview#a6 the US rate of neonatal sepsis is around 2/1000 live births so around 0.2%. Given this, I wonder how applicable these results would be to neonates in the US.

It may be that because of diet or other factors, this just wouldn't be as useful in the US.

No, it suggests something in the US is vastly more effective in preventing sepsis than this probiotic concoction.

Re: A big, successful trial of probiotics

#16

The 9% placebo and even the 5% treatment sepsis rate seems very high. According to http://emedicine.medscape.com/article/978352-overview#a6 the US rate of neonatal sepsis is around 2/1000 live births so around 0.2%. Given this, I wonder how applicable these results would be to neonates in the US.

The US generally has clean water. The third world, and India in particular, frequently do not.

That said, the other immune boosts are interesting here. And what would be doubly interesting is to figure out probiotics that prevent allergies.

We've known for years that a child who is exposed to real illnesses in a dirty environment may die from that, but won't generally go on to develop asthma. In the developed world we have a lot of health problems coming from the immune system looking so hard for threats that it starts attacking your own body.

There is very, very good reason to believe that the right probiotics would solve this problem. However discovering what those probiotics are is not so simple...

Re: A big, successful trial of probiotics

#17
post #9

All the products containing Lactobacillus plantarum may see a boost in sales.

This strain is in milk kefir, no? Easy to cultivate at home. See also: http://www.bbc.co.uk/news/health-38800977 Water kefir is also available :)

> See also: http://www.bbc.co.uk/news/health-38800977

I don't see anything in the article about Lactobacillus plantarum, and there's quite a few strains of Lactobacillus out there.

Re: A big, successful trial of probiotics

#18
post #9

All the products containing Lactobacillus plantarum may see a boost in sales.

This strain is in milk kefir, no? Easy to cultivate at home. See also: http://www.bbc.co.uk/news/health-38800977 Water kefir is also available :)

Anecdotal: I recently started taking Milk Kefir and it has been a life changer. I never thought I had any problems till they were resolved by Kefir. Seen great improvements in energy levels and anxiety. It even fixed the minor IBS I had.

Re: A big, successful trial of probiotics

#19
post #9

Earlier quoted context omitted.

This strain is in milk kefir, no? Easy to cultivate at home. See also: http://www.bbc.co.uk/news/health-38800977 Water kefir is also available :)

> See also: http://www.bbc.co.uk/news/health-38800977 I don't see anything in the article about Lactobacillus plantarum, and there's quite a few strains of Lactobacillus out there.

List of all the strains: https://www.yemoos.com/pages/milk-kefir-strains

Re: A big, successful trial of probiotics

#20

All the products containing Lactobacillus plantarum may see a boost in sales.

When my son was born I did a bunch is research on probiotics with good scientific evidence of efficacy. I ended up getting him these which contain most of the promising/researched strains. It's also a liquid which helps in giving it to a baby. I'm pretty convinced that a good probiotic and Onega3 supliment are extremely beneficial. https://www.amazon.com/BIOAMICUS-COMPLETE-Toddler-Probiotic-...

I would have a hard time trusting amazon to sell the actual product here and not a knock off.
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