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A big, successful trial of probiotics

theatlantic.com

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Re: A big, successful trial of probiotics

#3
Here's the nature article (paywall): http://www.nature.com/nature/journal/vaop/ncurrent/full/natu...

"The special mixture included a probiotic called Lactobacillus plantarum ATCC-202195 combined with fructo-oligosaccharide (FOS), an oral synbiotic preparation developed by Dr. Panigrahi." (from https://medicalxpress.com/news/2017-08-probiotics-sepsis-inf...)

Decrease in other infections (respiratory and nasal) is particularly interesting to see.

Now I want a HN MD to weigh in.

Re: A big, successful trial of probiotics

#4

The study was done on newborns just starting breastfeeding, but doesn't say whether only vaginal births or if C-sections were included.

99.8% and 99.7% of the births were vaginal for those receiving the placebo and the probiotics, respectively.

https://www.nature.com/articles/nature23480.epdf

Re: A big, successful trial of probiotics

#6
The 9% placebo and even the 5% treatment sepsis rate seems very high. According to http://emedicine.medscape.com/article/978352-overview#a6 the US rate of neonatal sepsis is around 2/1000 live births so around 0.2%.

Given this, I wonder how applicable these results would be to neonates in the US.

Re: A big, successful trial of probiotics

#8

All the products containing Lactobacillus plantarum may see a boost in sales.

are there any though? From the article, it seems that they had to cultivate the colonies themselves.

Yes, you can find it in some probiotic supplements.

https://www.gardenoflife.com/content/product/dr-formulated-p...

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