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Scientists Reverse Brain Damage in Drowned Toddler?

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Re: Scientists Reverse Brain Damage in Drowned Toddler?

#251
post #247

Earlier quoted context omitted.

I get the freezing, why the freshwater? Saltwater can be a bit colder before ice, so wouldn't it be better?

I think the salt is an issue with regard to inhaling the water, not about the temperature.

Yes, you and zimpenfish are correct: getting salt in your lungs will almost certainly kill you, because it keeps drawing water from the blood through osmosis, and you'll continue to drown even after leaving the water.

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#252

Well, this event happens enough that it might be worth studying the benefit of oxygen therapy, but I'd be very careful about the conclusions you draw from this. Maybe the oxygen had a substantial positive effect, or maybe the child would've recovered on her own. We really don't know, since there are other reports of children who have good neurological outcome despite terrible prognosis [1] [2]. I'm suspicious because…

> However, don't forget that when a baby is left unsupervised and is submerged in a pool for 15 minutes, it's called neglect. Whoa there, slow down. Kids are quick. One moment, your three kids are happily watching Finding Dory on the tv, while you're making dinner. The next, only two are: the third has quietly wandered off. Unless you know the particulars, be very careful about tossing around words like 'neglect'.

Like, one consistent behavior of properly functioning toddlers is that when they see something they don't know about, they try to put it in their mouth. Most of the world is unknown. You know, with 100% certainty, that as soon as possible, they will move in some random direction and put the random object in their mouth. So one component of competent parent is ensuring the toddler doesn't move to some dangerous location and try to put the dangerous thing in their mouth.

Analogously, maintaining a nuclear power plant is a very involved procedure, and if key individuals neglect to pay attention to certain monitors for what what in other contexts is a short period of time, failure occurs.

Yes, it requires constant attention. Not giving the task the attention it needs is to fail to care for it properly.

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#253

Earlier quoted context omitted.

- do not apologize for spreading more information - this is hacker news I hope people are in it for some sort of rigor, not just for wow effect I forgot the 66min case, but that brings me to something I heard recently. Some paramedics said they managed to sustain some kid under cardiac arrest for 18 minutes (he had a nice if not full recovery). The average rule is that if heart has not restarted after 6 minutes, brai…

I can't speak intelligently to your questions, because I have no relevant first-hand experience or knowledge of CPR literature. My only point regarding > The average rule is that if heart has not restarted after 6 minutes, brain damage is irreversible is that it doesn't mean it's worthless to continue CPR. Different people have different preferences about how grievous an injury they would want to survive. Whether to…

A friend of mine had her heart restarted at age 40 after 20 minutes of resus by the excellent London Ambulance Service. Intensive Care then applied a cooling apparatus to drop brain temperature.

My friend was in a coma for 6 weeks and had brain damage because of the lack of oxygen.

On one hand, this was distressing because she lost mathematical ability. This prevented her working in her previous field as a chemistry researcher.

On the other hand, she switched to psychology via a one year Masters degree and is now working on a fascinating project on hacking the mind's compassion responses to activate the parasympathetic nervous system and damp down anxiety (sympathetic nervous system) triggered by cardiac damage.

Just saying that although brain damage sounds terrifying, people can and do cope with it.

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#254

Earlier quoted context omitted.

We have to separate the points here. "Hope" is a real, tangible thing, crucial in our lives, and provably effective. The question is do we need to accept quackery to have it? Is that sometimes the only way? I suspect the answer is, rarely. There is so much legit and exciting work being done w.r.t. TBIs that it seems we should not have to rely on it in this area. But that's a guess. Until you've walked in someone's sh…

Well, this is the basis for religion. I am an atheist, scientist (physics) and I used to actively discourage people from religion (which is pure quackery). This until I realized that religion helps people who do not want to otherwise think about the world around them. One of the people I managed to move away from religion and change his beliefs ended up deeply depressive. Another one was deeply unhappy with the chang…

I am not religious but I believe that some form of religion has been fundamental to the human species historically. Humans wouldn't have become humans without it. So it is a hard thing to give up.

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#255

Earlier quoted context omitted.

I obviously don't know anything regarding your mom's condition, but SAH (a form of hemorrhagic stroke) by itself can have very complete recovery. The real question is how much ischemic stroke there was with it. If the answer is "none", then, if she survives (scary caveat, obviously), then her recovery could be very very good. Having said that, ischemic injury is common (as is herniation, which is similarly permanent…

Thank you for the reply. I can't tell you how much it means to me, regardless of the outcome. I'm prepared for her to pass; she's in a coma and she's suffered brain damage, but I'm doing my best to advocate for her.

Toomuchtodo: I posted earlier in the thread about a friend who bounced back after brain damage following a cardiac arrest.

The time when I didn't know the extent of the damage (would my friend ever wake up) was terrifying. The thought of a decision I might have to make as "next of kin" was worse.

I feel for your situation. I'm sure you will do the best thing you can do. Happy to chat - email is in my profile.

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#256

Earlier quoted context omitted.

I obviously don't know anything regarding your mom's condition, but SAH (a form of hemorrhagic stroke) by itself can have very complete recovery. The real question is how much ischemic stroke there was with it. If the answer is "none", then, if she survives (scary caveat, obviously), then her recovery could be very very good. Having said that, ischemic injury is common (as is herniation, which is similarly permanent…

Thank you for the reply. I can't tell you how much it means to me, regardless of the outcome. I'm prepared for her to pass; she's in a coma and she's suffered brain damage, but I'm doing my best to advocate for her.

[deleted]

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#257

Disclaimer: I am a neurologist The enthusiastic replies on this thread are understandable, but disappointing to see: we all need to be less credulous regarding the lay science press, and especially the lay medical press. I would love nothing more than to have this kind of therapy be a reality for my patients. However, I am deeply skeptical of this report. Why? Because - hyperbaric oxygen therapy has a big industry of…

*This observation was used to pursue hypothermia in other causes of anoxic injury, which is clinically used today. With pretty astounding results, honestly. My son was born having been without oxygen for at least 6-9 minutes. He was immediately put on a "cold blanket" with his temperature maintained at 92 (F) for 72 hours to prevent brain damage... He has since made a complete recovery with no physical neurological i…

I'm very glad for the outcome your son and family experienced, but can hardly imagine the horror that you went through in that 72 hours and subsequent time until you became assured of the outcome.

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#258
post #241

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What does it mean when you say you marked it as off topic? I don't see any such notes even in incognito, I'm not sure what it means.

"Marked as off-topic" means tagged as off-topic in HN's software, which causes it to fall in rank on the page.

Oh I see, cool, thanks!

Edit: I couldn't even post this because I've been supposedly "posting too fast" when I've only had ~5 comments in the last day. Are you causing/influencing/related to this in some way? I had never seen this happen before but ever since our last conversation I have seen it happen twice, both when you have been around the thread.

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#259
post #233

Earlier quoted context omitted.

> The arguer's credibility does not affect the truth value of any statements It is evidence which you should weigh in deciding how much credence to give their statements. > so it's always more useful to argue over why someone is wrong. It's a tradeoff, so there's no obvious bright line with which everyone will agree. But certainly there are some people for which some arguments or claims can be reasonably dismissed ou…

If it's evidence, then it must have an effect on the truth or falsity of the statements. So if X says "the sky is blue" then X's credibility must be causally related to whether or not the sky is blue. As there's no such mechanism, this is pointless. You essentially point out that it's an easy shortcut. And it is, but there's no good reason to take it. One's feelings of credibility do not change the truth value of any…

When presented with a statement, what matters is the probability that the statement is true. The credibility of a source is strong evidence in this regard and can be used to sway the probability mightily. You're right, of course, that arguing over the credibility is pointless, but an appeal to authority is not fallacious if you and I both agree on the authority.

(Though an appeal to authority is a perfect setup for a motte-and-bailey, so it's important to be wary. Also, it is not, nor ever can be, proof, since that should hold irrespective of authority.)

Re: Scientists Reverse Brain Damage in Drowned Toddler?

#260

Earlier quoted context omitted.

I can't speak intelligently to your questions, because I have no relevant first-hand experience or knowledge of CPR literature. My only point regarding > The average rule is that if heart has not restarted after 6 minutes, brain damage is irreversible is that it doesn't mean it's worthless to continue CPR. Different people have different preferences about how grievous an injury they would want to survive. Whether to…

A friend of mine had her heart restarted at age 40 after 20 minutes of resus by the excellent London Ambulance Service. Intensive Care then applied a cooling apparatus to drop brain temperature. My friend was in a coma for 6 weeks and had brain damage because of the lack of oxygen. On one hand, this was distressing because she lost mathematical ability. This prevented her working in her previous field as a chemistry…

Yep.

I had a teacher in grade school and one day she didn't come back to class, she had had a gigantic stroke. 6 months later she rolled into class in a wheelchair, a changed person, she could not speak or do basic tasks for herself.

Over the next two years she relearned most of her abilities, walking, talking, thinking, speaking, teaching and was back to "normal" again. Then she had another stroke.

She did not give up, and did it all over again.

She was always a cruel teacher in my eyes (I was very young) but seeing her persist throughout what I would assume would permanently put you out to pasture was an amazing experience and I always had enormous respect for her.

She continued teaching and retired ~20 years later.

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