There will be the usual walk through the park of unusable vectors to solve this. The only thing that could stop this is direct action - meaning, editing organisms to resist humanity. Making trees fireproof, equipping animals with diseases. The only wulf to hold back man, is another man.
Human beings have the (rarely used) capacity to improve the quality and usability of our surroundings. If at some point in the future, we should collectively decide to rehabilitate this planet of ours, mutant poisonous kudzu and HIV-reservoir mosquitoes will not make the work any easier.