From what I've read so far, this is pretty freaking cool. It's super interesting to read these docs and see their thought process involved, especially since the product their building is so different from what people are making on a day to day business. It actually looks pretty fun to work on. Also, I think it's neat to read about their need for developing frameworks that can be used around the agency to accomplish stuff.
Unfortunately, I didn't ready anything about self modifying code, which is probably the most difficult malware to detect and probably to write. Maybe it's in there though, I didn't read the whole document. I came to the comments about half way through to see dozens of people talking about whether they support Wikileaks or not which I think is fine, free country, but I'd like to actually know what some people who work with this kind of stuff think.
A framework for compiling to self modifying, yet correct, code wiukd be super cool. I wonder if it always has to be written by hand? Probably not but maybe that's a separate tool Wikileaks has yet to release.