Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Parkinson’s disease ‘may start in gut’

bbc.co.uk

Post reply on HN
Print view View original

121–130 of 139 posts

Re: Parkinson’s disease ‘may start in gut’

#121

Post by bArray »

pbhjpbhj wrote: post #19
bArray wrote: post #12

Earlier quoted context omitted.

Exactly my line of thinking. Sounds like a study should be done on the diets of those with Parkinson's compared to the "average" diet. There's a chance for too much or too little of something that could make a difference. I would also like to see a comprehensive study of the immune systems of those with and without, perhaps these people have little protection against these gut bacteria. The most interesting cases wou…

I can't imagine that diet and immune system studies haven't been done on Parkinson's sufferers?

Perhaps they have, but this new research may give more incentive to look much harder. If there is a link, I would imagine that it would not be trivial - otherwise as you say it would probably have been found.

Re: Parkinson’s disease ‘may start in gut’

#122

Post by kilroy123 »

natdempk wrote: post #117
kilroy123 wrote: post #114

Earlier quoted context omitted.

I worked with a guy who has Parkinson's. He was _obsessed_ with nutrition and always said the same thing about it being related to his gut. I don't think I've ever seen someone eat as natural and health as this guy. I'm obviously not a doctor and don't know, but from what I saw, he barely shook at all. He swore that when he went off his diet he would start shaking again. He also said his doctor couldn't believe how w…

Is there a general overview of the scientific claims made in this book somewhere? It sounds somewhat promising, but the table of contents doesn't exactly inspire confidence that the information is accurate. Additionally, I can't find any reviews online about this that don't look like shills for the book itself.

I'll be honest, I'm a layman and don't know. There are loads of Amazon reviews, but I agree not the best source and could be shills. I read the book and not too much seems crazy or out there.

https://www.amazon.com/dp/B00D8N6HBM/ref=dp-kindle-redirect?...

Re: Parkinson’s disease ‘may start in gut’

#123

Post by mderazon »

mahyarm wrote: post #106
sushid wrote: post #102

To those familiar with various skin conditions, this may not be a big surprise Skin conditions such as seborrheic dermatitis disproportionately affect those with HIV or Parkinson's and those skin conditions themselves have been liked to gut health, although not widely received in the medical community. Seeing as how many skin ailments are linked to those with early or long term use to antibiotics (e.g. childhood ear…

So how do you go about actually fixing it? I've had that condition in a minor form for pretty much my entire life, getting worse when I was a teenager. I've gone to many derms and they all end up just giving me some form of corticosteroids. I've tried vegan diets, various supplements, probiotics, natrual paths, salt baths, oatmeal baths and on and on, and it doesn't do much other than treat symptoms. I haven't tried…

Same like you. Have tried a lot of things. I am certain it has to do with my diet. I tried switching it and change it occasionally but could never nail what affected the it. Lots of people also say it has to do with stress but not to my personal experience. It's not that I don't get stressed, it's just that I've seen it come out bad in calm periods of my life as well. Another factor that I think affects it is weather. I find .y condition to improve greatly when I'm in a dry area like a desert.

I also started taking curcumin pills and I think that it also help.

The problem with seborrheic dermatitis is that its right on the edge between not bad enough to make you want to change your life significantly and annoying enough to make you suffer

Re: Parkinson’s disease ‘may start in gut’

#124

Post by tshadley »

natdempk wrote: post #117
kilroy123 wrote: post #114

Earlier quoted context omitted.

I worked with a guy who has Parkinson's. He was _obsessed_ with nutrition and always said the same thing about it being related to his gut. I don't think I've ever seen someone eat as natural and health as this guy. I'm obviously not a doctor and don't know, but from what I saw, he barely shook at all. He swore that when he went off his diet he would start shaking again. He also said his doctor couldn't believe how w…

Is there a general overview of the scientific claims made in this book somewhere? It sounds somewhat promising, but the table of contents doesn't exactly inspire confidence that the information is accurate. Additionally, I can't find any reviews online about this that don't look like shills for the book itself.

A rather fascinating article on Dr. Kharrazian was saved by the internet archive here: https://web.archive.org/web/20130924001750/http://scienceque...

"Having read his book in full [“Why Do I Still Have Thyroid Symptoms? When My Lab Tests are Normal"], visited one of his practitioners, and assembled the above lists of fraud indicators, I can solidly claim that Dr. Kharrazian is a quack." -- Dr. Christopher S. Baird

But note: Dr Baird deleted this article shortly after it was written in 2013.

Re: Parkinson’s disease ‘may start in gut’

#125

Post by pizza »

NickM wrote: post #100
trendia wrote: post #40

Earlier quoted context omitted.

If it's ketones, then it would be easy to train a dog to detect it.

I don't see any mention of ketones in the BBC article. What led you to that hypothesis?

Not GP but ketones have a fairly distinct and strong aroma. That said, if it were ketones, they'd probably be too distinguishable for this story to be uniquely news-worthy.. it's probably a less identifiable smell than ketones, whatever it is..

Re: Parkinson’s disease ‘may start in gut’

#126

Post by nonbel »

sushid wrote: post #104
nonbel wrote: post #44

Has anyone noticed how quickly a new research direction gets connected to all the big diseases? It has only been a few years since microbiome research really became a thing. It is disconcertingly fad-like. From pubmed: pubmed - human microbiome year count 2017 27 2016 5464 2015 5544 2014 4283 2013 2993 2012 2064 2011 1405 2010 910 2009 679 2008 520 2007 392 2006 290 2005 245 2004 160 2003 135 2002 118 2001 74 2000 78…

I don't think it's a fad, but a new causal link that's helping us understand the root cause of various ailments better. We've found a new root cause and that's very important. What you're saying is akin to someone in the 19th century saying that the new germ theory "fad" is being applied as the root cause to various diseases/deaths.

>"We've found a new root cause and that's very important."

The problem is the next big thing to get a bunch of funding will also be a "root cause", and the next, and the next... Also, they will all be 100% correct in saying this medley of factors is related to parkinsons/cancer/etc. The trouble is, identifying "root causes" isn't what this research should be focused on. I explained more in my later post in this thread.

Re: Parkinson’s disease ‘may start in gut’

#127

Post by pizza »

spangry wrote: post #113
tcj_phx wrote: post #64

Earlier quoted context omitted.

> He was pretty "normal" before the surgery but after it he couldn't walk and thought the hospital staff attacked him with dogs during the night. Apparently delirium is a common side effect of whatever they do in hospitals. I came across this link last month: "Delirium: A Surprising Side Effect of Hospital Stays -- Often misdiagnosed as dementia, it can cause hallucinations and delusions" - http://www.nextavenue.org/…

To be honest, is seems more likely the 'delirium' is actually mild psychosis brought on by excess dopamine in the PDF in particular. Many Parkinson's medicines treat some of the cognitive deficits it can cause with stuff like L-Dopa and other 'pro dopamine' drugs. Given the brain is progressively becoming more 'dysfunctional', some abnormal brain functionality + excess synaptic dopamine is probably psychosis waiting…

PDF? Do you mean PFC?

Re: Parkinson’s disease ‘may start in gut’

#128

Post by zevyoura »

zdean wrote: post #81
apinstein wrote: post #33

My Dad was recently diagnosed. Very early stage. This is very interesting news. My take is that Parkinson's is a little like cancer in that it likely has multiple root causes that can injure the same part of the brain (substantia niagra) and cause the disease. My research for his case led me to vitamin k2 deficiency as a possible cause / complicating factor. There are some genetic models and mouse trials that show k2…

I'm very sorry about your father's diagnosis. A few years ago I came across this spoon invention which seemed to be very helpful to those that are dealing with the shaking symptoms: http://www.gyenno.com/spoon-en

See also liftware.com

Re: Parkinson’s disease ‘may start in gut’

#129

Post by j_koreth »

tshadley wrote: post #124
natdempk wrote: post #117

Earlier quoted context omitted.

Is there a general overview of the scientific claims made in this book somewhere? It sounds somewhat promising, but the table of contents doesn't exactly inspire confidence that the information is accurate. Additionally, I can't find any reviews online about this that don't look like shills for the book itself.

A rather fascinating article on Dr. Kharrazian was saved by the internet archive here: https://web.archive.org/web/20130924001750/http://scienceque... "Having read his book in full [“Why Do I Still Have Thyroid Symptoms? When My Lab Tests are Normal"], visited one of his practitioners, and assembled the above lists of fraud indicators, I can solidly claim that Dr. Kharrazian is a quack." -- Dr. Christopher S. Baird B…

>But note: Dr Baird deleted this article shortly after it was written in 2013.

Doesn't that invalidate his claim if he had retracted it?

Re: Parkinson’s disease ‘may start in gut’

#130

Post by tshadley »

j_koreth wrote: post #129
tshadley wrote: post #124

Earlier quoted context omitted.

A rather fascinating article on Dr. Kharrazian was saved by the internet archive here: https://web.archive.org/web/20130924001750/http://scienceque... "Having read his book in full [“Why Do I Still Have Thyroid Symptoms? When My Lab Tests are Normal"], visited one of his practitioners, and assembled the above lists of fraud indicators, I can solidly claim that Dr. Kharrazian is a quack." -- Dr. Christopher S. Baird B…

>But note: Dr Baird deleted this article shortly after it was written in 2013. Doesn't that invalidate his claim if he had retracted it?

Deletion doesn't necessarily mean retraction. As far as I know, only a retraction strictly means retraction.

The article makes plenty of factual claims that remain factual whether the article is published or merely preserved.

Like: "autism is caused by genetic mutations, not “vaccines” or “leaky gut” as [Kharrazian] states on p.327 and 409."

And sure enough: [“Why Do I Still Have Thyroid Symptoms? When My Lab Tests are Normal“] searchable at Amazon does indeed have the claim that autism might be a result of immune system reaction to vaccine. Sure sounds like a quack.

https://www.amazon.com/Still-Thyroid-Symptoms-Tests-Normal/d...

Post reply on HN