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Exercise Releases Brain-Healthy Protein

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Re: Exercise Releases Brain-Healthy Protein

#101

Post by _0w8t »

searine wrote: post #81
quantumhobbit wrote: post #13

Earlier quoted context omitted.

Prehistoric humans likely exercised as a matter of course. They weren't sedentary. The brain evolved assuming the condition of exercise. naturally occurring byproducts of exercise were just always there for the brain to use.

You are assuming Hunter/Gatherers expend more energy than modern humans, which is not true ( http://journals.plos.org/plosone/article?id=10.1371/journal.... ) Physical activity levels were also within a standard deviation of one another (between western and h/g populations). The brain evolved in similar conditions to modern man. I would argue current conditions are far better for the brain in terms of good nutrition…

This does not imply that, for example, a daily or weekly peak of energy expenditure was the same. As training once per week for 15 minutes with weights is enough to grow muscles, it could be that hunter/gatheres needed to release energy at the max level like running away from a lion much more often than we do nowdays and during those releases the brain also had to work hardest.

Re: Exercise Releases Brain-Healthy Protein

#102

Post by evm9 »

chipsy wrote: post #88
wallace_f wrote: post #74

Earlier quoted context omitted.

>Not something you'd want to achieve repeatedly. My memory is telling me that studies of exercise show the longest living are those that do anything from endurance to what the article below calls "mixed" sports. Powerlifting and high intensity training may offer some benefit, but it is not as much as endurance training. What I found in a quick Google search to attempt to refresh my memory, is in agreement: http://wel…

This correlates with my personal experience. Lifting is a good idea, but my optimum for it is perhaps once a week, else I fall into overtraining. The rest of the time when I want to exercise mild cardio seems more beneficial.

Maybe that works for you, but you'll never be strong/look strong weight training weekly. If you're "overtraining" from one weight training session per week, there's something very wrong. The average human only takes 48-72 hours to fully recover for most muscle groups in the body.

It's also been proven that HIIT is much more beneficial for your system than LISS.

It might "seem" more beneficial to you, but likely is not more beneficial than the alternatives. However, something is definitely better than nothing, and do what works for you and makes you happy.

Re: Exercise Releases Brain-Healthy Protein

#103

Post by schappim »

For all the entrepreneurs wanting to bottle Cathepsin B (the "Brain-Healthy Protein"), unfortunately it has also been linked with tumour invasion and metastasis[1]. Further study is needed to know if the increase in Cathepsin B is a factor or simply correlation.

[1] http://www.ncbi.nlm.nih.gov/pubmed/14587299

Re: Exercise Releases Brain-Healthy Protein

#104

Post by searine »

_0w8t wrote: post #101
searine wrote: post #81

Earlier quoted context omitted.

You are assuming Hunter/Gatherers expend more energy than modern humans, which is not true ( http://journals.plos.org/plosone/article?id=10.1371/journal.... ) Physical activity levels were also within a standard deviation of one another (between western and h/g populations). The brain evolved in similar conditions to modern man. I would argue current conditions are far better for the brain in terms of good nutrition…

This does not imply that, for example, a daily or weekly peak of energy expenditure was the same. As training once per week for 15 minutes with weights is enough to grow muscles, it could be that hunter/gatheres needed to release energy at the max level like running away from a lion much more often than we do nowdays and during those releases the brain also had to work hardest.

>during those releases the brain also had to work hardest

That is speculation, and is unintuitive. Why would the brain "work hardest" when running? Why would modern humans not exert the same forces during sport? Why would humans, the top group-oriented predator, run from a lion?

The data linked above shows that observed Physical Activity Levels and caloric use are comparable to modern day. Stop inserting your own assumptions into the data.

Re: Exercise Releases Brain-Healthy Protein

#105

Post by damienkatz »

TeMPOraL wrote: post #64
damienkatz wrote: post #56

Earlier quoted context omitted.

Wondering if you might have an undiagnosed medical condition. I've been very a active exerciser my whole adult life. It's part of my identity. Last year I started suffering from chronic fatigue. Exercise began to hurt. It hurt when I did it. It hurt afterward. I was tired all the time. I was gaining weight. I stopped exercising. It brought me no relief. Only resting did. I knew something was wrong. Went to Doctor. Tr…

Might be. I'm planning to do thyroid tests soon, because some of the things in my life could be explained by problems there, and my sister recently found out she has some thyroid problems. I understand the experience - for me, day-and-night difference was getting on SSRIs. But it could also just be that I never started to like exercising in the first place. I have myopia since early childhood - so from the first year…

The reason I wrote my long response was because you said exercise was painful. Sure, if you overdo it, it can be painful to anyone. But it's not supposed to painful. Uncomfortable sure, tiring sometimes yes.

But not painful. Afterward you should feel alert and relaxed. And in reasonable amounts it should feel like it is increasing what you can get done. Usually anyway.

If not, something is wrong. Hopefully something that can be treated.

Good luck to you! Health can be very tricky. In so many ways health and wellness is still in the dark ages. So many incomplete models and misinformation. I've been there and feel bad for anyone else bewildered because they don't fit into mainstream ideas of how their bodies are supposed to work.

Re: Exercise Releases Brain-Healthy Protein

#106

Post by rconti »

ams6110 wrote: post #32
Johnie wrote: post #28

Earlier quoted context omitted.

It adds cost to the healthcare system and to health insurance that company pay when so many people are unhealthy.

Yes it does, but we've brought that on ourselves by insisting that pre-existing conditions (such as obesity, high blood presssure, etc.) cannot be cause to deny coverage or charge higher premiums. Smoking, interestingly, seems to be an exception to that standard.

God forbid you switch jobs after getting sick.

As long as we have largely employer-based healthcare, the pre-existing conditions exemption is asinine.

Maybe once we have an actual market, we can talk about re-introducing it.

Re: Exercise Releases Brain-Healthy Protein

#107

Post by pizza »

mathattack wrote: post #96

There is a strange dichotomy here... I do believe that exercise helps thinking, but when I was growing up, very few of the smarter people were involved in sports, either formally or informally. Perhaps 1 in 20 was on a team, and few were that active otherwise. The link to drama and music was much bigger.

Percentage of high school seniors who participated in various school-related extracurricular activities, by sex: 1990 and 2001 - https://nces.ed.gov/programs/youthindicators/Indicators.asp?...

If artistic ability has a strong influence on intelligence compared to athleticism, then P(intelligent | artistic) >= P(intelligent | athletic). We know that P(athletic) > P(artistic) from the data.

By Bayes' theorem:

P(intelligent | artistic) = P(artistic | intelligent) * P(intelligent) / P(artistic).

P(intelligent | athletic) = P(athletic | intelligent) * P(intelligent) / P(athletic).

Ignoring P(intelligent) for a sec, we find

P(intelligent | artistic) ~ P(artistic | intelligent) / P(artistic)

P(intelligent | athletic) ~ P(athletic | intelligent) / P(athletic)

If we accept the assumption that artistic ability is a bigger influence, then

P(artistic | intelligent) / P(artistic) > P(athletic | intelligent) / P(athletic)

Because P(athletic) > P(artistic),

P(artistic | intelligent) > P(artistic) * P(athletic | intelligent) / P(athletic)

P(artistic)/P(athletic) must be less than 1, so we get

P(artistic | intelligent) > P(athletic | intelligent)

I'm not really sure where I was headed with this, but it was neat to think about. If anyone spots an error please just correct me.

Re: Exercise Releases Brain-Healthy Protein

#108

Post by mightybyte »

TeMPOraL wrote: post #23
laxatives wrote: post #16

Earlier quoted context omitted.

Because an enormous chunk of the population still refuses to exercise and/or diet and articles like this help motivate some of that subset.

Or piss them off. Exercise is tiring and painful and time-consuming (especially if you count in after-exercise showers). Also, I don't like the whole culture around exercising and fitness. Gimme a damn pill or something. More seriously though, I really find no pleasure in exercise and would like to approach it in the most cost-effective way (i.e. maximum benefit for minimum time used). Any hints on exercise regime op…

CrossFit. It is the most time efficient all-around fitness program I have run across. And they're the ONLY methodology I've seen that has an actual measurable definition of the fitness they seek.

Re: Exercise Releases Brain-Healthy Protein

#109

Post by mathattack »

ethanbond wrote: post #98
mathattack wrote: post #96

There is a strange dichotomy here... I do believe that exercise helps thinking, but when I was growing up, very few of the smarter people were involved in sports, either formally or informally. Perhaps 1 in 20 was on a team, and few were that active otherwise. The link to drama and music was much bigger.

Probably because you're talking about academic success which is only loosely correlated to intelligence, and almost entirely not correlated to "brain health." "Brain health," as it's used in this article, would also contribute to coordination, muscle control, and various other things that would benefit athletes in ways that are totally opaque to you or me. The article doesn't say exercise makes you smarter , and even…

Fair point. I guess by smart I'm thinking "least work for best grades" but that's a very loose definition.

Also - it's a very small sample size. And if I look more broadly... 2 of the seemingly "dumbest jocks" I knew in college went on to become doctors, one at the Mayo clinic. So perhaps their intelligence was showing in other areas until they got out of school.

Re: Exercise Releases Brain-Healthy Protein

#110

Post by mathattack »

codyb wrote: post #97
mathattack wrote: post #96

There is a strange dichotomy here... I do believe that exercise helps thinking, but when I was growing up, very few of the smarter people were involved in sports, either formally or informally. Perhaps 1 in 20 was on a team, and few were that active otherwise. The link to drama and music was much bigger.

Is it possible kids maintain a higher rate of metabolic activity just by growing thus offsetting some of the activity you don't see in children with above average intelligence?

It could be. Also could be a low sample size. :-)
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