I know friends who have always loved programming and will continue till last breath living happily in their world of programming (which is huge these days).
I also know dear friends who have got the most advanced degree's irrelevant to computer science and yet are dreaming to be a programmer.
All said, what can one conclude from Mr Andrew Wulf's judgement of his life? I'm thinking about the answer as I'm writing this... hmm what does this tell me... perhaps not much else that there exist another person who regret his past decision, true or false, the chances are that it is applicable to anyone including me is as much as how much Mr Andrew Wulf's complexity of life and his state of mind are similar to others reading it.